Thyroid volume in Turkish school-age children living in an iodine-sufficient region
-
Reyhan Deveci Sevim
,
Mustafa Gök
,
Sercan Öztürk
,
Özge Çevik
,
Ömer Erdoğan
,
Sebla Güneş
,
Tolga Ünüvar
und
Ahmet Anık
Abstract
Objectives
We aimed to obtain local normative data on thyroid volume evaluated by ultrasonography and iodine status by measuring urine iodine levels in school-age children living in Aydın province.
Methods
In this cross-sectional study, a sample comprising 1,553 cases was meticulously selected from a total cohort of 170,461 children aged 6–17, drawn from 21 distinct educational institutions located within the Aydın region, as participants in the investigation. Those with a known chronic disease or thyroid disease were excluded from the study. The children underwent physical examinations and ultrasonography imaging of the thyroid gland, and urine samples were collected to measure urinary iodine concentration (UIC).
Results
The median UIC was 189.5 (IQR=134.4) μg/L, which was optimal according to WHO criteria. Thyroid volume was found to be 4.6 (IQR=3.5) mL in girls and 4.2 (IQR=4.0) mL in boys (p=0.883). The thyroid volumes in our study were found to be smaller when compared to the WHO. According to WHO age and body surface area criteria, thyroid volume was over 97 % in 0.9 % (n=15) of cases. Thyroid volume was found to have a positive correlation with age, height, weight, body mass index (BMI), and body surface area (BSA) in both genders (p<0.001). However, there was no significant correlation between thyroid volume and UIC.
Conclusions
This cross-sectional study provides normative data on thyroid volume and iodine status in school-age children in iodine-sufficient population, revealing a low prevalence of goiter and correlations between thyroid volume and anthropometric measures.
Funding source: Adnan Menderes Ãœniversitesi
Award Identifier / Grant number: TPF-21022
Acknowledgments
We are grateful to Utku Agca for his contribution to the study.
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Research ethics: The study was conducted in accordance with the Declaration of Helsinki and was approved by the non-interventional ethics committee of Aydın Adnan Menderes University (Ethics no: 2021/147). Participants were informed about the purpose of the study and gave their consent for the utilization of their medical data and those of their children for research purposes.
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Informed consent: Informed consent in this study was taken from all participants.
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Author contributions: Reyhan DEVECİ SEVİM collected the data and wrote the manuscript; Mustafa GÖK performed ultrasonographic imaging of the thyroid and wrote the manuscript; Sercan ÖZTÜRK collected the data and made statistical analysis; Özge ÇEVİK and Ömer ERDOĞAN made laboratory analyses; Sebla GÜNEŞ collected the data; Tolga ÜNÜVAR read and approved manuscript; Ahmet ANIK designed research and edited the manuscript; all authors read and approved manuscript.
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Competing interests: The authors state no conflict of interest.
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Research funding: The work was supported by the Aydın Adnan Menderes University Scientific Projects Unit (grant number TPF-21022). The funding organization played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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Data availability: Not applicable.
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© 2024 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
- Frontmatter
- Editorial
- Insulin for “hearts that had lost hope” – on the first pediatric patients and the 1923 Nobel Prize in Physiology or Medicine
- Reviews
- The effect of gonadotropin-releasing hormone analog treatment on the endocrine system in central precocious puberty patients: a meta-analysis
- Artificial intelligence in paediatric endocrinology: conflict or cooperation
- Original Articles
- A pilot study proposing an algorithm for pubertal induction in cerebral palsy
- Thyroid volume in Turkish school-age children living in an iodine-sufficient region
- Hypothyroxinemia and weight velocity in preterm infants
- Factors associated with neonatal hyperinsulinemic hypoglycemia, a case-control study
- Predictive factors for lung metastasis in pediatric differentiated thyroid cancer: a clinical prediction study
- Case Reports
- Two Turkish patients with Primary Coenzyme Q10 Deficiency-7: case report and literature review
- Hereditary spastic paraplegia type 35 in a Turkish girl with fatty acid hydroxylase-associated neurodegeneration
- A case report of odonto-hypophosphatasia with a novel variant in the ALPL gene
- Neuronal ceroid lipofuscinosis type 11 diagnosed patient with bi-allelic variants in GRN gene: case report and review of literature
- Diagnosis and approach of pseudohypoparathyroidism type 1A and related disorders during long term follow-up: a case report
Artikel in diesem Heft
- Frontmatter
- Editorial
- Insulin for “hearts that had lost hope” – on the first pediatric patients and the 1923 Nobel Prize in Physiology or Medicine
- Reviews
- The effect of gonadotropin-releasing hormone analog treatment on the endocrine system in central precocious puberty patients: a meta-analysis
- Artificial intelligence in paediatric endocrinology: conflict or cooperation
- Original Articles
- A pilot study proposing an algorithm for pubertal induction in cerebral palsy
- Thyroid volume in Turkish school-age children living in an iodine-sufficient region
- Hypothyroxinemia and weight velocity in preterm infants
- Factors associated with neonatal hyperinsulinemic hypoglycemia, a case-control study
- Predictive factors for lung metastasis in pediatric differentiated thyroid cancer: a clinical prediction study
- Case Reports
- Two Turkish patients with Primary Coenzyme Q10 Deficiency-7: case report and literature review
- Hereditary spastic paraplegia type 35 in a Turkish girl with fatty acid hydroxylase-associated neurodegeneration
- A case report of odonto-hypophosphatasia with a novel variant in the ALPL gene
- Neuronal ceroid lipofuscinosis type 11 diagnosed patient with bi-allelic variants in GRN gene: case report and review of literature
- Diagnosis and approach of pseudohypoparathyroidism type 1A and related disorders during long term follow-up: a case report
