Startseite Clinical correlation of 2D shear wave elastography findings in children with type 1 diabetes mellitus without autoimmune thyroiditis
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Clinical correlation of 2D shear wave elastography findings in children with type 1 diabetes mellitus without autoimmune thyroiditis

  • Hanife Gülden Düzkalır ORCID logo EMAIL logo , Ömer Aydıner ORCID logo , Elif Söbü ORCID logo und Rıdvan Dizman
Veröffentlicht/Copyright: 9. März 2023
Journal of Pediatric Endocrinology and Metabolism
Aus der Zeitschrift Journal of Pediatric Endocrinology and Metabolism Band 36 Heft 4

Abstract

Objectives

The aim of study was to evaluate the 2D shear wave sonoelastography (SWE) findings of the thyroid gland in children with type 1 diabetes mellitus (T1DM) with normal gray-scale findings and without thyroid autoimmunity (AIT) and obtain data that will be useful for the early detection of glandular involvement.

Methods

The study included 46 T1DM patients (mean age: 11.28 ± 3.3 years) and 46 healthy children (mean age: 12.01 ± 3.8 years) as the control group. The thyroid gland mean elasticity value was obtained as kPa and compared in groups. A correlation was investigated between elasticity values and age at diabetes, serum free T4, thyroid stimulating hormone (TSH), anti-thyroglobulin, anti-tissue peroxidase, and hemoglobin A1c values.

Results

No difference was found between T1DM patients and the control group in the thyroid 2D SWE evaluation (the median kPa value: 17.1 (10.2) in the study group and 16.8 (7.0) in the control group) (p=0.15). No significant correlation was found between 2D SWE kPa values and age at diagnosis, serum free T4, TSH, anti-thyroglobulin, anti-tissue peroxidase, and hemoglobin A1c levels in T1DM patients.

Conclusions

Our study showed that the elasticity of the thyroid gland in T1DM patients without AIT was not affected differently from that of the normal population. If 2D SWE is used in routine follow-up in T1DM patients before the development of AIT, we think that it will be useful in the early detection of thyroid gland affections and AIT, and long-term comprehensive studies in this direction will contribute to the literature.

Keywords: children; sonoelastography; thyroid; tissue elasticity imaging; type 1 diabetes mellitus
Corresponding author: Hanife Gülden Düzkalır, Department of Radiology, Kartal Dr. Lütfi Kırdar City Hospital, Şemsi Denizer Cad. E-5 Karayolu Cevizli Mevkii 34890 Kartal- İstanbul, Istanbul, Türkiye, Phone: +90(216)4583000, E-mail:

  1. Research funding: None declared.

  2. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Conflicts of interests: Authors state no conflict of interest.

  4. Informed consent: Informed consent was obtained from all individuals included in this study.

  5. Ethical approval: This article does not contain any studies with human participants or animals performed by any of the authors. This study was approved by the local medical Ethical Committee, and all data was processed anonymously, according to the privacy legislation.

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Received: 2023-01-12
Accepted: 2023-02-20
Published Online: 2023-03-09
Published in Print: 2023-04-25

© 2023 Walter de Gruyter GmbH, Berlin/Boston

Artikel in diesem Heft

  1. Frontmatter
  2. Reviews
  3. Approach to nutritional rickets
  4. Subclinical hyperthyroidism in children
  5. Original Articles
  6. Can thyroid elastography with ultrasound be used to stage children with Hashimoto’s thyroiditis?
  7. Congenital hypothyroidism in children with eutopic gland or thyroid hemiagenesis: prognostic factors for transient vs. permanent hypothyroidism
  8. Comparison of developmental outcomes in children with permanent and transient congenital hypothyroidism
  9. Impact of overweight and obesity on epicardial adipose tissue in children with type 1 diabetes
  10. Peripheral arterial disease among children with type 1 diabetes mellitus in a Nigerian teaching hospital
  11. The WHO-5 well-being questionnaire in type 1 diabetes: screening for depression in pediatric and young adult subjects
  12. Clinical correlation of 2D shear wave elastography findings in children with type 1 diabetes mellitus without autoimmune thyroiditis
  13. Molecular analysis of MKRN3 gene in Turkish girls with sporadic and familial idiopathic central precocious puberty
  14. Case Reports
  15. ALG11-CDG: novel variant and review of the literature
  16. Betamethasone cream to treat diapers rash causing Cushing syndrome
  17. Rapid-onset obesity, hypothalamic dysfunction, hypoventilation, and autonomic dysregulation syndrome – neuro-endocrine tumours (ROHHAD-NET): case series and learning points
  18. Lathosterolosis: a rare cholesterol metabolism disorder with a wide range of clinical variability
  19. Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1
https://doi.org/10.1515/jpem-2023-0019
Schlagwörter für diesen Artikel
children; sonoelastography; thyroid; tissue elasticity imaging; type 1 diabetes mellitus

Artikel in diesem Heft

  1. Frontmatter
  2. Reviews
  3. Approach to nutritional rickets
  4. Subclinical hyperthyroidism in children
  5. Original Articles
  6. Can thyroid elastography with ultrasound be used to stage children with Hashimoto’s thyroiditis?
  7. Congenital hypothyroidism in children with eutopic gland or thyroid hemiagenesis: prognostic factors for transient vs. permanent hypothyroidism
  8. Comparison of developmental outcomes in children with permanent and transient congenital hypothyroidism
  9. Impact of overweight and obesity on epicardial adipose tissue in children with type 1 diabetes
  10. Peripheral arterial disease among children with type 1 diabetes mellitus in a Nigerian teaching hospital
  11. The WHO-5 well-being questionnaire in type 1 diabetes: screening for depression in pediatric and young adult subjects
  12. Clinical correlation of 2D shear wave elastography findings in children with type 1 diabetes mellitus without autoimmune thyroiditis
  13. Molecular analysis of MKRN3 gene in Turkish girls with sporadic and familial idiopathic central precocious puberty
  14. Case Reports
  15. ALG11-CDG: novel variant and review of the literature
  16. Betamethasone cream to treat diapers rash causing Cushing syndrome
  17. Rapid-onset obesity, hypothalamic dysfunction, hypoventilation, and autonomic dysregulation syndrome – neuro-endocrine tumours (ROHHAD-NET): case series and learning points
  18. Lathosterolosis: a rare cholesterol metabolism disorder with a wide range of clinical variability
  19. Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1
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