Children and adolescents with type 1 diabetes in Germany are more overweight than healthy controls: results comparing DPV database and CrescNet database
-
Thomas M. Kapellen
,
Ruth Gausche
Abstract
Aims: To describe the development of weight in children and adolescents with type 1 diabetes in Germany.
Methods: We analyzed the body mass index (BMI) of the most recent treatment year of each patient with diabetes in the Pediatric Quality Initiative (DPV) database. BMI SD score (SDS) was calculated based on pooled historical German normative data (AGA) and based on healthy children from the CrescNet database. Thus, 25,762 children and adolescents with diabetes were compared with more than 75,000 healthy controls.
Results: BMI-SDS was 0.49±0.88 and 0.26±0.79 when children and adolescents, respectively, with diabetes were compared with AGA reference or with CrescNet controls from the same year. In both analyses, female patients (0.57±0.89 and 0.30±0.79) had significantly higher BMI-SDS than male patients (0.41±0.86 and 0.22±0.78; p<0.0001). Analysis of different age groups showed highest BMI-SDS in patients below 6 years (0.61 and 0.56, respectively). After adjustment for metabolic control, center, and insulin treatment, BMI-SDS was significantly influenced by diabetes duration, age, and female gender.
Conclusions: BMI of children and adolescents with type 1 diabetes is higher compared with healthy children measured in the same year. Especially, very young children and adolescent girls are at risk for overweight independent of annual trends.
Acknowledgments
We thank all the pediatricians and endocrinologists of CrescNet for their collaboration and data collection and all sponsors of this network (www.crescnet.org) for their support.
The DPV-Science-Initiative was supported by the German Federal Ministry of Health for the BMBF Kompetenznetz Obesity (FKZ 01GI0824) and the BMBF Kompetenznetz Diabetes (FKZ 02GI0859), Novo Nordisk Germany, Dr. Bürger-Büsing Foundation, Bundesärztekammer, German National Aktion Forum Diabetes Mellitus, and German Diabetes Foundation.
We thank the pediatric diabetes centers from the following cities for collaboration in the DPV-Science-Initiative and for participating in this study.
There is no conflict of interest for the authors relevant for this project.
Aachen - Uni-Kinderklinik RWTH, Aalen Kinderklinik, Ahlen St. Franziskus Kinderklinik, Altötting Zentrum Inn-Salzach, Aue Helios Kinderklink, Augsburg Innere/Kinderklinik Zentralklinikum, Aurich Kinderklinik, Bad Aibling Internist. Praxis, Bad Hersfeld Kinderklinik, Bad Kösen Kinder-Rehaklinik, Bad Lauterberg Diabeteszentrum Innere, Bad Oeynhausen Diabetesfachklinik, Bad Waldsee Kinderarztpraxis, Bautzen Oberlausitz KK, Berchtesgaden CJD, Berlin DRK-Kliniken, Berlin Kinderklinik Lindenhof, Berlin St. Josephskrankenhaus Innere, Berlin Virchow-Kinderklinik, Berlin-Hellersdorf Innere Bielefeld Kinderklinik Gilead, Bocholt Kinderklinik, Bochum Universitätskinderklinik St. Josef, Bonn Uni-Kinderklinik, Bottrop Kinderklinik, Bottrop Knappschaftskrankenhaus Innere, Bremen - Kinderklinik Nord, Bremen Kinderklinik St.Jürgenstrasse, Bremerhaven Kinderklinik, Celle Kinderklinik, Chemnitz Kinderklinik, Coesfeld Kinderklinik, Darmstadt Innere Medizin/Kinderklinik Prinz. Margareth, Datteln Vestische Kinderklinik, Deggendorf Kinderarztpraxis, Deggendorf Kinderklinik, Delmenhorst Kinderklinik, Detmold Kinderklinik, Dornbirn Kinderklinik, Dortmund Kinderklinik, Dortmund-St. Josefshospital Innere, Dresden Neustadt Kinderklinik, Dresden Uni-Kinderklinik, Duisburg Evang. und Johanniter Krhs, Innere, Düren-Birkesdorf Kinderklinik, Düsseldorf Uni-Kinderklinik, Erfurt Kinderklinik, Erlangen Uni-Kinderklinik, Essen Diabetes-Schwerpunktpraxis Essen Elisabeth Kinderklinik, Essen Uni-Kinderklinik, Esslingen Städtische Kinderklinik, Eutin Kinderklinik, Frankenthal Kinderarztpraxis, Frankfurt Uni-Klinik Innere, Freiburg Uni Innere, Freiburg Uni-Kinderklinik, Friedberg Innere Klinik, Friedrichshafen Kinderklinik Fulda Innere Medizin/ Kinderklinik, Fürth Kinderklinik, Gaissach Fachklinik, Garmisch-Partenkirchen Kinderklinik, Gelnhausen Kinderklinik, Gelsenkirchen Kinderklinik Marienhospital, Gießen Uni-Kinderklinik, Graz Universitäts-Kinderklinik, Göppingen Innere Medizin, Göppingen Kinderklinik am Eichert, Görlitz Städtische Kinderklinik, Göttingen Uni-Kinderklinik, Hachenburg Kinderpraxis, Hagen Kinderklinik, Halle Uni-Kinderklinik, Halle-Dölau Städtische Kinderklinik, Hamburg Altonaer Kinderklinik, Hamburg Endokrinologikum, Hamburg Kinderklinik Wilhelmstift, Hamburg-Nord Kinderklinik Heidberg, Hamm Kinderklinik, Hanau Kinderklinik, Hannover Kinderklinik MHH, Hannover Kinderklinik auf der Bult, Heidelberg Uni-Kinderklinik, Heidenheim Kinderklinik, Heilbronn Innere Klinik, Heilbronn Kinderklinik, Herdecke Kinderklinik, Herford Kinderarztpraxis, Herford Kinderklinik, Heringsdorf Inselklinik, Hermeskeil Kinderpraxis, Hildesheim Innere, Hildesheim Kinderarztpraxis, Hildesheim Kinderklinik, Hinrichsegen-Bruckmühl Diabetikerjugendhaus, Homburg Uni-Kinderklinik Saarland, Idar Oberstein Innere, Innsbruck Universitätskinderklinik, Itzehoe Kinderklinik, Jena Uni-Kinderklinik, Kaiserslautern-Westpfalzklinikum Kinderklinik, Karlsburg Klinik für Diabetes & Stoffwechsel, Karlsruhe Städtische Kinderklinik, Kassel Kinderklinik Park Schönfeld, Kassel Städtische Kinderklinik, Kaufbeuren Innere Medizin, Kempen Heilig Geist - Innere, Kiel Städtische Kinderklinik, Kiel Universitäts-Kinderklinik, Kirchen DRK Klinikum Westerwald, Kinderklinik, Kirchheim-Nürtingen Innere, Koblenz Kemperhof 1. Med. Klinik, Koblenz Kinderklinik Kemperhof, Krefeld Innere Klinik, Krefeld Kinderklinik, Köln Kinderklinik Amsterdamerstrasse, Köln Uni-Kinderklinik, Landshut Kinderklinik, Leipzig Uni-Kinderklinik, Leverkusen Kinderklinik, Lindenfels Luisenkrankenhaus Innere, Lingen Kinderklinik St. Bonifatius, Lippstadt Evangelische Kinderklinik, Ludwigsburg Kinderklinik, Ludwigshafen Kinderklinik St.Anna-Stift, Lübeck Uni-Kinderklinik, Lüdenscheid Kinderklinik, Magdeburg Uni-Kinderklinik, Mainz Uni-Kinderklinik, Mannheim Uni-Kinderklinik, Marburg Uni-Kinderklinik, Mechernich Kinderklinik, Memmingen Kinderklinik, Merzig Kinderklinik, Minden Kinderklinik, Moers Kinderklinik, Mutterstadt Kinderarztpraxis, Mönchengladbach Kinderklinik Rheydt Elisabethkrank, München 3. Orden Kinderklinik, München Diabetes-Zentrum Süd, München von Haunersche Kinderklinik, München-Gauting Kinderarztzentrum, München-Harlaching Kinderklinik, München-Schwabing Kinderklinik, Münster St. Franziskus Kinderklinik, Münster Uni-Kinderklinik, Münster pädiat. Schwerpunktpraxis, Neuburg Kinderklinik, Neunkirchen Kinderklinik Kohlhof, Neuss Lukaskrankenhaus Kinderklinik, Neuwied Kinderklinik Elisabeth, Nürnberg Cnopfsche Kinderklinik, Nürnberg Kinderklinik Klinikum Süd, Oberhausen Kinderklinik, Oberhausen Kinderpraxis Bachran, Offenbach/Main Kinderklinik, Offenburg Kinderklinik, Oldenburg Kinderklinik, Osnabrück Kinderklinik, Osterkappeln Innere, Paderborn St. Vincenz Kinderklinik, Papenburg Marienkrankenhaus Kinderklinik, Passau Kinderarztpraxis Handwerker, Passau Kinderklinik, Pforzheim Kinderklinik, Rastatt Gemeinschaftspraxis, Ravensburg Kinderklink St. Nikolaus, Recklinghausen Dialysezentrum Innere, Regensburg Kinderklinik St. Hedwig, Remscheid Kinderklinik, Rendsburg Kinderklinik, Reutlingen Klinikum Steinenberg Innere, Rheine Mathiasspital Kinderklinik, Rosenheim Innere Medizin, Rosenheim Kinderklinik, Rosenheim Schwerpunktpraxis, Rostock Uni-Kinderklinik, Rotenburg/Wümme Kinderklinik, Rüsselsheim Kinderklinik, Saaldorf-Surheim Diabetespraxis, Saalfeld Thüringenklinik Kinderklinik, Saarbrücken Kinderklinik Winterberg, Saarlouis Kinderklinik, Scheidegg Reha-Kinderklinik Maximilian, Schw. Gmünd Margaritenhospital Kinderklinik, Schweinfurt Kinderklinik, Schwerin Innere Medizin, Schwerin Kinderklinik, Siegen Kinderklinik, Singen - Hegauklinik Kinderklinik, Sinsheim Innere, Spaichingen Innere, St. Augustin Kinderklinik, Stade Kinderklinik, Stolberg Kinderklinik, Stuttgart Olgahospital Kinderklinik, Suhl Kinderklinik, Sylt Rehaklinik, Tettnang Innere Medizin, Traunstein Praxis Dr. Voll, Trier Kinderklinik der Borromäerinnen, Trostberg Innere, Tübingen Uni-Kinderklinik, Ulm Uni-Kinderklinik, Vechta Kinderklinik, Viersen Kinderklinik, Villingen-Schwenningen Schwarzwald-Baar-Klinikum I, Waiblingen Kinderklinik, Waldshut Kinderpraxis Biberbau, Weiden Kinderklinik, Weingarten Kinderarztpraxis, Wernberg-Köblitz SPP, Wien Uni-Kinderklinik, Wiesbaden Horst-Schmidt-Kinderkliniken, Wiesbaden Kinderklinik DKD, Wilhelmshafen Reinhard-Nieter-Kinderklinik, Wittlich Innere Medizin, Worms Kinderklinik, Wuppertal Kinderklinik.
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- Masthead
- Masthead
- Images in pediatric endocrinology
- Leprechaunism (Donohue syndrome): report of a case in a newborn
- Original articles
- Children and adolescents with type 1 diabetes in Germany are more overweight than healthy controls: results comparing DPV database and CrescNet database
- Age of onset of pubertal maturation of Thai boys
- Plasma leptin and adiponectin concentrations correlate with cardiometabolic risk and systemic inflammation in healthy, non-obese children
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- Effect of micronutrient supplementation on height velocity of underprivileged girls in comparison with un-supplemented healthy controls
- Insulin resistance in young adults born small for gestational age (SGA)
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- Health-related quality of life in Turner syndrome and the influence of key features
- Clinical analysis on 33 patients with hypothalamic syndrome in Chinese children
- The relationship between thyroid dose and diagnosis of primary hypothyroidism in pediatric brain tumor patients receiving craniospinal irradiation
- Molecular characterization of Chilean patients with a clinical diagnosis of Noonan syndrome
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