Abstract
Eleven species of Huilliche medicinal plants used traditionally against infections and for wound healing were tested for their cholinesterase inhibition activity. Two different teas (a 5–7 min infusion and a 1 h decoction, both in water) were tested for their toxicity against Artemia salina. The results from the present study clearly show that teas boiled for 1 h is much more toxic than teas infused for 5–7 min. These results support the different traditional use of the two teas, where the 1h tea is for external use only. Additionally, significant inhibition of cholinesterase has been observed for MeOH extracts of Acaena argentea, Amomyrtas meli and Pseudopanax laetevirens, with that of A. argentea being the most potent. All findings call for further investigations.
Acknowledgement
This work was supported by the Beckett-Foundation (HTS).
References
1. Houghton PJ, Manby J. Medicinal plants of the Mapuche. J Ethnopharmacol 1985;13:89–103.10.1016/0378-8741(85)90063-7Suche in Google Scholar
2. Estomba D, Ladio A, Lozada M. Medicinal wild plant knowledge and gathering patterns in a Mapuche community from North-western Patagonia. J Ethnopharmacol 2006;103:109–19.10.1016/j.jep.2005.07.015Suche in Google Scholar
3. Molares S, Ladio A. Chemosensory perception and medicinal plants for digestive ailments in a Mapuche community in NW Patagonia, Argentina. J Ethnopharmacol 2009;123:397–406.10.1016/j.jep.2009.03.033Suche in Google Scholar
4. Mølgaard P, Holler JG, Asar B, Liberna I, Rosenbæk LB, Jebjerg CP, et al. Antimicrobial evaluation of Huilliche plant medicine used to treat wounds. J Ethnopharmacol 2011;138:219–27.10.1016/j.jep.2011.09.006Suche in Google Scholar
5. Simonsen HT, Adsersen A, Berthelsen L, Christensen SB, Guzman A, Mølgaard P. Ethnopharmacological evaluation of radal (leaves of L. hirsuta) and isolation of 2-methoxyjuglone. BMC Complementary and Altern Med 2006;6:29.10.1186/1472-6882-6-29Suche in Google Scholar
6. Simonsen HT, Riedel C, Gade LB, Jebjerg CP, Guzman A, Mølgaard P. Chemical composition and antibacterial activity of the leaf essential oil of Baccharis magellanica (Lam.) Pers. and Baccharis elaeoides Remy from Chile. J Essent Oil Res 2009;21:377–80.10.1080/10412905.2009.9700196Suche in Google Scholar
7. Mendoza L, Wilkens M, Urzúa A. Antimicrobial study of the resinous exudates and of diterpenoids and flavonoids isolated from some Chilean Pseudognaphalium (Asteraceae). J Ethnopharmacol 1997;58:85–8.10.1016/S0378-8741(97)00084-6Suche in Google Scholar
8. Urzúa A, Torres R, Muñoz M, Palacios Y. Comparative antimicrobial study of the resinous exudates of some Chilean Haplopappus (Asteraceae). J Ethnopharmacol 1995;45:71–4.10.1016/0378-8741(94)01196-7Suche in Google Scholar
9. Urzúa A, Jara F, Tojo E, Wilkens M, Mendoza L, Rezende MC. A new antibacterial clerodane diterpenoid from the resinous exudate of Haplopappus uncinatus. J Ethnopharmacol 2006;103:297–301.10.1016/j.jep.2005.09.042Suche in Google Scholar PubMed
10. Falkenberg SS, Tarnow I, Guzman A, Mølgaard P, Simonsen, HT. Mapuche herbal medicine inhibits blood platelet aggregation. Evid Based Complement Altern Med 2012;2012:1–9.10.1155/2012/647620Suche in Google Scholar PubMed PubMed Central
11. Schmeda-Hirschmann G, Loyola JI, Sierra J, Retamal R, Rodriguez J. Hypotensive effect and enzyme inhibition activity of mapuche medicinal plant extracts. Phytother Res 1992;6:184–8.10.1002/ptr.2650060404Suche in Google Scholar
12. Barboza GE, Cantero JJ, Núñez C, Pacciaroni A, Ariza Espinar L. Medicinal plants: a general review and a phytochemical and ethnopharmacological screening of the native Argentine Flora. Kurtziana 2009;34:7–365.Suche in Google Scholar
13. Torri MC. Medicinal plants used in mapuche traditional medicine in Araucanía, Chile: linking sociocultural and religious values with local heath practices. Complement Health Pract Rev 2010;15:132–48.10.1177/1533210110391077Suche in Google Scholar
14. Niero R, Faloni de Andrade S, Cechinel Filho, V. A Review of the Ethnopharmacology, Phytochemistry and Pharmacology of Plants of the Maytenus Genus. Curr Pharm Des 2011;17:1851–71.10.2174/138161211796391029Suche in Google Scholar
15. Wagner H, Bladt S. Plant drug analysis. Berlin: Springer-Verlag, 2001.Suche in Google Scholar
16. Rhee IK, van de Meent M, Ingkaninan K, Verpoorte R. Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining. J Chromatogr A 2001;915:217–23.10.1016/S0021-9673(01)00624-0Suche in Google Scholar
17. Risa A, Risa J, Adsersen A, Stafford GI, Staden Jv, Jäger AK. Acetylcholinesterase inhibitory activity of plants used as memory-enhancers in traditional South African medicine. S Afr J Bot 2004;70:664–6.10.1016/S0254-6299(15)30208-8Suche in Google Scholar
18. 18. Orhan I, Sener B, Choudhary MI, Khalid A. Acetylcholinesterase and butyrylcholinesterase inhibitory activity of some Turkish medicinal plants. J Ethnopharmacol 2004;91:57–60.10.1016/j.jep.2003.11.016Suche in Google Scholar PubMed
19. Martín JS. Medicinal plants in Central Chile. Econ Bot 1983;37:216–27.10.1007/BF02858788Suche in Google Scholar
20. Silva F, Ullrich T, Hartman P, Medina H, Moraga L. Plantas medicinales de la region de aysen – Chile Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas 2004;3:36–45.Suche in Google Scholar
21. Baireddy P, Liu J, Hinsdale M, Pope C. Comparative effects of chlorpyrifos in wild type and cannabinoid Cb1 receptor knockout mice. Toxicol Appl Pharmacol 2011;256:324–9.10.1016/j.taap.2011.05.018Suche in Google Scholar PubMed PubMed Central
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- Chemical and pharmacological standardization of Ashwagandhadi lehyam: an ayurvedic formulation
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- Hypoglycemic activity of the Anisopus mannii N. E. Br. methanolic leaf extract in normal and alloxan-induced diabetic mice
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