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Prevalence and distribution of causes of infertility according to women’s age – a cross-sectional study in a tertiary healthcare hospital setup

  • Keerthana Dhandapani , Bhagyalakshmi Kodavanji EMAIL logo , Vinodini Nithyananda Madom Anantharaya and Nayanatara Arun Kumar ORCID logo
Published/Copyright: June 29, 2021
Journal of Basic and Clinical Physiology and Pharmacology
From the journal Journal of Basic and Clinical Physiology and Pharmacology Volume 34 Issue 1

Abstract

Objectives

Infertility has disastrous consequences, particularly for women. Causes of infertility in developed countries have been investigated but there is a significant lack of data among Indian female population. The aim of the present study was to analyze the causes and the proportion of the individual factors contributing to infertility, considering the age factor.

Methods

The data of 204 infertile women (18–45 years) were collected from the files in tertiary care hospitals. Causes and age of infertile women were grouped. The prevalence of each cause was evaluated. Data analysis was done using SPSS (Statistical Package for Social Sciences) version 17.0.

Results

Polycystic ovarian syndrome (PCOS) was the most common (14.71%) cause of female infertility. Ovulatory dysfunctions (25.55%) were the foremost cause in primary infertility, whereas in secondary infertility, uterine factors (26.86%) were most common. The incidence of primary and secondary infertility was more evident in patients who were more than 30 years of age.

Conclusions

Causes of infertility vary according to the age. The causes of female infertility were unexplained infertility, ovulatory disorders and uterine factors most commonly affecting women at ≤30 years.

Keywords: age; infertility; primary infertility; secondary infertility
Corresponding author: Bhagyalakshmi Kodavanji, Department of Physiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India, Phone: +919449468282, E-mail:

Acknowledgment

All the authors thank the Manipal Academy of Higher Education for providing all the facilities needed for this research work.

  1. Research funding: None declared.

  2. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Conflict of interest: All the authors hereby declare that there are no conflicts of interest.

  4. Informed consent: Informed consent was obtained from all individuals included in this study.

  5. Ethical approval: All the procedures performed in this present study were in agreement with the ethical guidelines as per the institutional ethics committee and the ethical approval (RefNumber: IEC.KMC MLR 10-13/179, dated 16th October 2013) was taken before the study procedures.

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Received: 2020-11-10
Accepted: 2021-05-16
Published Online: 2021-06-29

© 2021 Walter de Gruyter GmbH, Berlin/Boston

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  10. Supplementation of antihypertensive drug regimen with vitamin E ameliorates alterations of primary haemodynamic parameters and total antioxidant capacity in ovariectomised rats
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https://doi.org/10.1515/jbcpp-2020-0349
Keywords for this article
age; infertility; primary infertility; secondary infertility

Articles in the same Issue

  1. Frontmatter
  2. Editorial
  3. Peyronie’s disease: where are we at?
  4. Reviews
  5. Catheter-associated urinary tract infection: an overview
  6. Liver and heart failure: an ultrasound relationship
  7. Original Articles
  8. The intracellular fluid compartment is smaller than commonly believed when measured by whole-body bioimpedance
  9. Prevalence and distribution of causes of infertility according to women’s age – a cross-sectional study in a tertiary healthcare hospital setup
  10. Supplementation of antihypertensive drug regimen with vitamin E ameliorates alterations of primary haemodynamic parameters and total antioxidant capacity in ovariectomised rats
  11. Analgesic effect of curcumin topical formulation in knee osteoarthritis patients: a clinical trial
  12. ProACT in the management of stress urinary incontinence after radical prostatectomy. What happens after 8 years of follow up? monocentric analysis in 42 patients
  13. The effect of metformin on the metabolism of human vascular smooth muscle cells in high glucose conditions
  14. Physiological response of endurance exercise as a growth hormone mediator in adolescent women’s
  15. Effect of Om chanting and Yoga Nidra on depression anxiety stress, sleep quality and autonomic functions of hypertensive subjects – a randomized controlled trial
  16. Effectiveness of electrical vestibular nerve stimulation as adjunctive therapy to improve the cognitive functions in patients with Parkinson’s disease
  17. Role of interleukin-22 in tuberculosis patients
  18. Effect of aspirin on the TNF-α-mediated cell survival and death pathways in breast cancer
  19. Resting heart rate variability as a diagnostic marker of cardiovascular dysautonomia in postural tachycardia syndrome
  20. Effects of intensity and training on cardiovascular responses to the Valsalva maneouvre
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