Comparative assessment of onion and garlic extracts on endogenous hepatic and renal antioxidant status in rat

References

1. Bordia A, Verma SK, Srivastava KC. Effect of garlic (Allium sativum) on blood sugar, fibrinogen and fibrinolytic activity in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty Acids 1998;58:257–63.10.1016/S0952-3278(98)90034-5Search in Google Scholar

2. Ugwu CE, Omale J. Comparative effects of aqueous garlic (Allium sativum) and onion (Allium cepa) extracts on some haematological and lipid indices of rats. Ann Rev Res Biol 2011;1:37–44.Search in Google Scholar

3. Liu L, Yeh YY. S-alk(en)yl cysteines of garlic inhibit cholesterol synthesis by deactivating HMG-CoA reductase in cultured rat hepatocytes. J Nutr 2002;132:1129e1134.10.1093/jn/132.6.1129Search in Google Scholar PubMed

4. Harauma A, Moriguchi T. Aged garlic extract improves blood pressure in spontaneously hypertensive rats more safely than raw garlic. J Nutr 2006;136:769Se773S.10.1093/jn/136.3.769SSearch in Google Scholar PubMed

5. Eidi A, Eidi M, Esmaeili E. Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin-induced diabetic rats. Phytomedicine 2006;13:624–9.10.1016/j.phymed.2005.09.010Search in Google Scholar PubMed

6. Weiss N, Ide N, Abahji T, Nill L, Keller C, Hoffmann U. Aged garlic extract improves homocysteine-induced endothelial dysfunction in macro- and microcirculation. J Nutr 2006;136:750Se754S.10.1093/jn/136.3.750SSearch in Google Scholar PubMed

7. Rose P, Whiteman M, Moore PK, Zhu YZ. Bioactive salk (en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Nat Prod Rep 2005;22:351e368.10.1039/b417639cSearch in Google Scholar PubMed

8. Griffiths G, Trueman L, Crowther T, Thomas B, Smith B. Onions – A global benefit to health. Phytother Res 2002;16:603–15.10.1002/ptr.1222Search in Google Scholar PubMed

9. Galeone C, Pelucchi C, Levi F, Negri E, Franceschi S, Talamini R, et al. Onion and garlic use and human cancer. Am J Clin Nutr 2006;84:1027–32.10.1093/ajcn/84.5.1027Search in Google Scholar PubMed

10. Corzo-Martinez M, Corzo N, Villamiel M. Biological properties of onions and garlic. Food Sci Technol 2007;18:609–25.10.1016/j.tifs.2007.07.011Search in Google Scholar

11. Suru SM. Onion and garlic extracts lessen cadmium-induced nephrotoxicity in rats. Biometals 2008;21:623–33.10.1007/s10534-008-9148-5Search in Google Scholar PubMed

12. Obioha UE, Suru SM, Ola-Mudathir KF, Faremi TY. Hepatoprotective potentials of onion and garlic extracts on cadmium-induced oxidative damage in rats. Biol Trace Elem Res 2009;129:143–56.10.1007/s12011-008-8276-7Search in Google Scholar

13. Nose K. Role of reactive oxygen species in the regulation of physiological functions. Biol Pharm Bull 2000;23:897–903.10.1248/bpb.23.897Search in Google Scholar

14. Polidori MC, Stahl W, Eichler O, Niestroj I, Sies H. Profiles of antioxidants in human plasma. Free Radic Biol Med 2001;30:456–62.10.1016/S0891-5849(00)00345-2Search in Google Scholar

15. Augusti KT, Mathew PT. Lipid lowering effect of allicin (diallyl disulfide oxide) on long-term feeding in normal rats. Experientia 1974;30:468e470.10.1007/BF01926297Search in Google Scholar

16. Shashikanth KW, Basappa SC, Murthy VS. Effect of feeding raw versus boiled garlic (A. sativum L.) extracts on the growth, caecal microflora and serum proteins of albino rats. Nutr Rep Int 1986;33:313–9.Search in Google Scholar

17. Kleijnen J, Knipscnild P, Terriet G. Garlic, onion and cardiovascular risk factors. A review of the evidence from human experiments with emphasis on commercially available preparations. Br J Clin Pharmacol 1989;28:535–44.10.1111/j.1365-2125.1989.tb03539.xSearch in Google Scholar

18. Augusti KT. Therapeutic values of onion (Allium cepa L.) and garlic (Allium sativum L.). Indian J Exp Biol 1996;34:634–40.Search in Google Scholar

19. El-Demerdash FM, Yousef MI, Abou El-Naga NI. Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats. Food Chem Toxicol 2005;43:57–63.10.1016/j.fct.2004.08.012Search in Google Scholar

20. Brzoska MM, Moniuszko-Jakoniuk J, Pilat-Marcinkiewicz B, Sawicki B. Liver and kidney function and histology in rats exposed to cadmium and ethanol. Alcohol Alcoholism 2003;38:2–10.10.1093/alcalc/agg006Search in Google Scholar

21. Denton L, Ojeifo IM. 1990 Onion production practices and their improvement in Nigeria. Onion Newsletter in Tropics 1990;2: 10–13.Search in Google Scholar

22. Gorinstein S, Leontowicz H, Leontowicz M, Namiesnik J, Najman K, Drzewiecki J, et al. Comparison of the main compounds and antioxidant activities in garlic and white and red onion after treatment protocols. J Agr Food Chem 2008;56:4418–26.10.1021/jf800038hSearch in Google Scholar

23. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265–75.10.1016/S0021-9258(19)52451-6Search in Google Scholar

24. Gutteridge J, Wilkins S. Copper dependent hydroxyl radical damage to ascorbic acid. FEBS Lett 1982;137:327–9.10.1016/0014-5793(82)80377-3Search in Google Scholar

25. Jollow DJ, Michell JR, Zampaglione N, Gillete J. Bromobenzene-induced liver necrosis: protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology 1974;11:151–69.10.1159/000136485Search in Google Scholar

26. Misra HP, Fridovich I. The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 1972;247:3170–5.10.1016/S0021-9258(19)45228-9Search in Google Scholar

27. Sinha KA. Colorimetric assay of catalase. Anal Biochem 1971;47:389–94.10.1016/0003-2697(72)90132-7Search in Google Scholar

28. Habig WH, Pabst MJ, Jakoby WB. The first enzymatic step in mercapturic acid formation. Anal Biochem 1974;249:7130–9.10.1016/S0021-9258(19)42083-8Search in Google Scholar

29. Adam-Vizi V, Seregi A. Receptor independent stimulatory effect of noradrenalin on Na⁺/K⁺-ATPase in rat brain homogenate, role of lipid peroxidation. Biochem Pharmacol 1982;31:2231–6.10.1016/0006-2952(82)90106-XSearch in Google Scholar

30. Stewart DJ. Sensitive automated methods for phosphate and (Na+ plus K+)-ATPase. Anal Biochem 1974;62:349–64.10.1016/0003-2697(74)90167-5Search in Google Scholar

31. Reitman S, Frankel S. A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminases. Am J Clin Pathol 1957;28:56–63.10.1093/ajcp/28.1.56Search in Google Scholar PubMed

32. Umakoshi H, Tanabe T, Suga K, Bui HT, Shimanouchi T, Kuboi R. Oxidative stress can affect the gene silencing effect of DOTAP liposome in an in vitro translation system. Int J Biol Sci 2011;7:253–60.10.7150/ijbs.7.253Search in Google Scholar PubMed PubMed Central

33. Halliwell B, Gutteridge JMC. Free radical biology and medicine, 3rd edition. Oxford University Press, 1999:105–245.Search in Google Scholar

34. Maria FN, Isabel S, Irene I, Juana B. Quercetin, a flavonoid antioxidant, prevents and protects against ethanol-induced oxidative stress in mouse liver. Biol Pharm Bull 2003;26:1398–402.10.1248/bpb.26.1398Search in Google Scholar PubMed

35. Adedara IA, Farombi EO. Induction of oxidative damage in the testes and spermatozoa and hematotoxicity in rats exposed to multiple doses of ethylene glycol monoethyl ether. Hum Exp Toxicol 2010;29:801–12.10.1177/0960327109360115Search in Google Scholar PubMed

36. Bang MA, Kim HA, Cho YJ. Alterations on the blood glucose serum lipids and renal oxidative stress in diabetic rats by supplementation of onion (Allium Cepa. Linn). Nutr Res Pract 2009;3:242–6.10.4162/nrp.2009.3.3.242Search in Google Scholar PubMed PubMed Central

37. Lee B, Jung J, Kim H. Assessment of red onion on antioxidant activity in rat. Food Chem Toxicol 2012;50:3912–9.10.1016/j.fct.2012.08.004Search in Google Scholar

38. Banerjeea SK, Maulik M, Manchanda SC, Dinda AK, Das TK, Maulik SK. Garlic-induced alteration in rat liver and kidney morphology and associated changes in endogenous antioxidant status. Food Chem Toxicol 2001;39:793–7.10.1016/S0278-6915(01)00018-7Search in Google Scholar

39. Hamby-Mason R, Chen JJ, Schenker S, Perez A, Henderson GI. Catalase mediates acetaldehyde formation from ethanol in fetal and neonatal rat brain. Alcohol Clin Exp Res 1997;21: 1063–72.10.1111/j.1530-0277.1997.tb04255.xSearch in Google Scholar

40. Ji X, Zhang P, Armstrong RN, Gilliland GL. The 3 dimensional structure of a glutathione S-transferase from the Mu gene class. Structural analysis of the binary complex of isoenzyme 3-3 and glutathione at 2.2-A° resolution. Biochemistry 1992;31:10169–84.10.1021/bi00157a004Search in Google Scholar

41. Guyonnet D, Siess MH, Le Bon AM, Suschetet M. Modulation of phase II enzymes by organosulfur compounds from Allium vegetables in rat tissues. Toxicol Appl Pharmacol 1999;154:50–8.10.1006/taap.1998.8574Search in Google Scholar

42. Teyssier C, Amiot MJ, Mondy N, Kahane R, Siess MH. Effect of onion consumption by rats on hepatic drug metabolizing enzymes. Food Chem Toxicol 2001;39:981–7.10.1016/S0278-6915(01)00056-4Search in Google Scholar

43. Thomson M, Alnaqeeb MA, Bordia T, Al-Hassan JM, Afzal M, Ali M. Effects of aqueous extract of onion on the liver and lung of rats. J Ethnopharmacol 1998;61:91–9.10.1016/S0378-8741(98)00004-XSearch in Google Scholar

44. El-Manakhly EM, Youssef SA, Hassieb MM. The protective effect of garlic against carbon tetrachloride induced hepatotoxicosis in male rat. Some histopathologic and histochemical studies. Egyptian J Comparative Pathol Clin Pathol 1998;11:35–45.Search in Google Scholar

45. Nuutila AM, Puuponen-Pimia R, Aarni M, Oksman-Caldentey K. Comparison of antioxidant activities of onion and garlic and extracts by inhibition of lipid peroxidation and radical scavenging activity. Food Chem 2003;81:485–93.10.1016/S0308-8146(02)00476-4Search in Google Scholar

46. Kumari K, Augusti KT. Anti-diabetic and antioxidant effects of S-methyl cysteine sulfoxide isolated from onions (Allium cepa L.) as compared to standard drugs in alloxan diabetic rats. Indian J Exp Biol 2002;40:1005–9.Search in Google Scholar

47. Murugavel P, Pari L. Diallyl tetrasulfide modulates the cadmium-induced impairment of membrane bound enzymes in rats. J Basic Clin Physiol Pharmacol 2007;18:37–48.10.1515/JBCPP.2007.18.1.37Search in Google Scholar PubMed

48. Whanger PD. Selenocompounds in plants and animals and their biological significance. J Am Coll Nutr 2002;21:223–32.10.1080/07315724.2002.10719214Search in Google Scholar PubMed

49. Nijveldt RJ, Van Nood E, Van Hooran DEC, Boelens PG, Van Norren K, Leeuwen PAM. Flavonoids: a review of probable mechanisms of action and potential applications. Am J Clin Nutr 2001;74:418–25.10.1093/ajcn/74.4.418Search in Google Scholar PubMed

50. Moskaug JO, Carlsen H, Myhrstad MCW, Blomhoff R. Polyphenols and glutathione synthesis regulation. Am J Clin Nutr 2005;81:277S–83S.10.1093/ajcn/81.1.277SSearch in Google Scholar PubMed

51. Goel A, Danni V, Dhawan DK. Protective effects of zinc on lipid peroxidation, antioxidant enzymes and hepatic histoarchitecture in chlorpyrifos-induced toxicity. Chem Biol Interact 2005;156:131–40.10.1016/j.cbi.2005.08.004Search in Google Scholar PubMed

52. Karaoz E, Gultekin F, Akdogan M, Oncu M, Gokcimen A. Protective role of melatonin and a combination of vitamin C and vitamin E on lung toxicity induced by chlorpyrifos-ethyl in rats. Exp Toxicol Pathol 2002;54:97–108.10.1078/0940-2993-00236Search in Google Scholar PubMed

53. Park J, Kim J, Kim MK. Onion flesh and onion peel enhance antioxidant status in aged rats. J Nutr Sci Vitaminol 2007;53:21–9.10.3177/jnsv.53.21Search in Google Scholar PubMed

54. Abdel-Wahhab MA, Aly SE. Antioxidants and radical scavenging properties of vegetable extracts in rats fed aflatoxin-contaminated diet. J Agr Food Chem 2003;51:2409–14.10.1021/jf0209185Search in Google Scholar PubMed

55. Durak I, Kavutcu M, Aytaç B, Avci A, Devrim E, Ozbek H, et al. Effects of garlic extract consumption on blood lipid and oxidant/antioxidant parameters in humans with high blood cholesterol. J Nutr Biochem 2004;15:373–7.10.1016/j.jnutbio.2004.01.005Search in Google Scholar PubMed

56. Crambert G, Hasler U, Beggah AT, Yu C, Modyanov NN, Horisberger J-D, et al. Transport and pharmacological properties of nine different human Na⁺/K⁺ATPase isoenzymes. J Biol Chem 2000;275:1976–86.10.1074/jbc.275.3.1976Search in Google Scholar PubMed

57. Kocak-Toker N, Giris M, Tulubas F, Uysal M, Aykac-Toker G. Peroxynitrite induced decrease in Na⁺/K⁺ATPase activity is restored by taurine. World J Gastroenterol 2005;11:3554–7.10.3748/wjg.v11.i23.3554Search in Google Scholar PubMed PubMed Central

58. Mense, Stark G and Apell HJ. Effects of free radicals on partial reactions of the Na⁺/K⁺ATPase. J Membr Biol 1997;156:63–71.10.1007/s002329900188Search in Google Scholar PubMed

59. Bhardwaj S, Srivastava MK, Kapoor U, Srivastava LP. A 90 days oral toxicity of imidacloprid in female rats: morphological, biochemical and histopathological evaluations. Food Chem Toxicol 2010;48:1185–90.10.1016/j.fct.2010.02.009Search in Google Scholar PubMed

60. Navarro CM, Montilla PM, Martin A, Jimenez J, Utrilla PM. Free radicals scavenger and antihepatotoxic activity of Rosmarinus. Plant Medicine 1993;59:312–4.10.1055/s-2006-959688Search in Google Scholar PubMed

61. Kaplan MM. Laboratory tests. In: Schiff L, Schiff ER, editors. Diseases of the liver, 7th edition. Philadelphia: JB Lippincott, 1993:108–44.Search in Google Scholar