Plant cell microcompartments: a redox-signaling perspective
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Sabine Zachgo
Sabine Zachgo studied Biology in Würzburg, Germany and at the Duke University, USA and conducted her PhD at the Max-Planck-Institute for Plant Breeding Research in Cologne. Since 2007 she has been Head of the Department of Botany and Director of the Botanical Garden at the University of Osnabrück. Her research field is plant developmental genetics. Recently, the lab found a novel, nuclear function for land-plant specific glutaredoxins from
Arabidopsis , the ROXYs, in flower development.Guy T. Hanke completed his PhD in Plant Physiology with Mike Emes and Caroline Bowsher at the University of Manchester in 1999. He then did short post-doctoral studies at the University of Cambridge, UK, Osaka University, Japan and the University of Manchester, UK. In 2002 he started a post-doc, and then an Assistant Professorship in the lab of Toshiharu Hase at the Institute for Protein Research, Osaka University, Japan. During this time he became fascinated by the regulation of electron partitioning in photosynthesis, and still focuses his research on this area. Since 2008 he has been a principle investigator in the Department of Plant Physiology, headed by Professor Renate Scheibe at the University of Osnabrück, Germany.
Renate Scheibe studied Pharmaceutical Chemistry in Munich, and then worked with Erwin Beck for her PhD in Plant Physiology at the Botanical Institute of the Ludwig Maximilian University (LMU), and later at the Universities of Illinois at Chicago and of Bayreuth. She received the
venia legendi in Botany in Bayreuth in 1984 and continued in the research group of Erwin Beck as an Assistant Professor working on light-dark modulation of chloroplast enzymes and also took part in ecophysiological studies of the afroalpine vegetation in East Africa. She is Head of the Department of Plant Physiology at the University of Osnabrück since 1990. Her research interest is the redox-regulation of basic metabolism in plants where her group studies the mechanisms of flexible adjustment of energy production and consumption at the various cellular levels.
Abstract
This review describes how transient protein-protein interactions can contribute to direct information flow between subsequent steps of metabolic and signaling pathways, focusing on the redox perspective. Posttranslational modifications are often the basis for the dynamic nature of such macromolecular aggregates, named microcompartments. The high cellular protein concentration promotes these interactions that are prone to disappear upon the extraction of proteins from cells. Changes of signaling molecules, such as metabolites, effectors or phytohormones, or the redox state in the cellular microenvironment, can modulate them. The signaling network can, therefore, respond in a very flexible and appropriate manner, such that metabolism, stress responses, and developmental steps are integrated by multiple and changing contacts between functional modules. This allows plants to survive and persist by continuously and flexibly adapting to a challenging or even adverse environment.
About the authors
Sabine Zachgo studied Biology in Würzburg, Germany and at the Duke University, USA and conducted her PhD at the Max-Planck-Institute for Plant Breeding Research in Cologne. Since 2007 she has been Head of the Department of Botany and Director of the Botanical Garden at the University of Osnabrück. Her research field is plant developmental genetics. Recently, the lab found a novel, nuclear function for land-plant specific glutaredoxins from Arabidopsis, the ROXYs, in flower development.
Guy T. Hanke completed his PhD in Plant Physiology with Mike Emes and Caroline Bowsher at the University of Manchester in 1999. He then did short post-doctoral studies at the University of Cambridge, UK, Osaka University, Japan and the University of Manchester, UK. In 2002 he started a post-doc, and then an Assistant Professorship in the lab of Toshiharu Hase at the Institute for Protein Research, Osaka University, Japan. During this time he became fascinated by the regulation of electron partitioning in photosynthesis, and still focuses his research on this area. Since 2008 he has been a principle investigator in the Department of Plant Physiology, headed by Professor Renate Scheibe at the University of Osnabrück, Germany.
Renate Scheibe studied Pharmaceutical Chemistry in Munich, and then worked with Erwin Beck for her PhD in Plant Physiology at the Botanical Institute of the Ludwig Maximilian University (LMU), and later at the Universities of Illinois at Chicago and of Bayreuth. She received the venia legendi in Botany in Bayreuth in 1984 and continued in the research group of Erwin Beck as an Assistant Professor working on light-dark modulation of chloroplast enzymes and also took part in ecophysiological studies of the afroalpine vegetation in East Africa. She is Head of the Department of Plant Physiology at the University of Osnabrück since 1990. Her research interest is the redox-regulation of basic metabolism in plants where her group studies the mechanisms of flexible adjustment of energy production and consumption at the various cellular levels.
©2013 by Walter de Gruyter Berlin Boston
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Artikel in diesem Heft
- Masthead
- Masthead
- Guest Editorial
- Highlight: The physiology and dynamics of cellular microcompartments
- Highlight: The Physiology and Dynamics of Cellular Microcompartments
- Cellular microcompartments constitute general suborganellar functional units in cells
- Dynamics of bioenergetic microcompartments
- Microcompartments within the yeast plasma membrane
- Plant cell microcompartments: a redox-signaling perspective
- Microcompartments in the Drosophila heart and the mammalian brain: general features and common principles
- Minireviews
- Beyond anemia: hepcidin, monocytes and inflammation
- Melanoma resistance to photodynamic therapy: new insights
- The biosynthesis of caprazamycins and related liponucleoside antibiotics: new insights
- cCMP, cUMP, cTMP, cIMP and cXMP as possible second messengers: Development of a hypothesis based on studies with soluble guanylyl cyclase α1β1
- Research Articles/Short Communications
- Protein Structure and Function
- Degradation of channelopsin-2 in the absence of retinal and degradation resistance in certain mutants
- Cell Biology and Signaling
- Possible role of a septin, SEPT1, in spreading in squamous cell carcinoma DJM-1 cells
- Proteolysis
- ADAMTS: Novel proteases expressed by activated mast cells
- The proinflammatory cytokines interleukin-1α and tumor necrosis factor α promote the expression and secretion of proteolytically active cathepsin S from human chondrocytes
