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MONOJO Biotech

  • Mohammad Z. Abu-Zaid EMAIL logo
Published/Copyright: August 9, 2013
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Company overview

MONOJO was established in 2005 to become a leader company in biotechnology. The company now epitomises the new concept of the knowledge-based economy.

MONOJO is dedicated on developing, manufacturing, and marketing its own safe and effective biotech innovations, such as, monoclonal antibodies for cancer diagnostics, cancer research, and other novel biopharmaceutical therapies to meet serious worldwide unmet needs and illnesses in the field of oncology, endocrinology, dermatology, gastroenterology, and infectious diseases.

MONOJO also provides unique training courses in the biotech and medical fields for public universities, medical sectors, and those running applied scientific research.

By 2009, MONOJO started to expand its biotech projects for more effective and efficient work by signing a MOU agreement with the Institute of Biotechnology of the University of Cambridge, UK, represented by its institute’s director and member of MONOJO’s Board of Directors and Scientific Advisor, Prof. Christopher Lowe for the purpose of collaboration in:

  • Facilitating experts and students from Cambridge Biotech Institute (UK) to share their expertise and knowledge.

  • Assisting MONOJO to increase its research capability through scientific visits and training for MONOJO staff either in-house or at the Cambridge Biotech Institute (UK).

  • Facilitating collaborative biotech research and projects between MONOJO and the University of Cambridge (UK).

MONOJO is currently a member of the UK BioIndustry Association; the association has enhanced MONOJO’s visibility, network, and relationships with business decision-makers in the UK and European bioscience industry.

The company operates in two main countries, in Jordan at our headquarters The MONOJO, where it constitutes the main company’s research and development (R&D) and its global business development and marketing operations department for its innovative bioproducts. Its second main base of operations is in the USA where MONOJO’s first subsidiary The Columbia Biotech complements MONOJO’s R&D Department and its business development and marketing operations.

MONOJO offers challenging and stimulating envi-ronments in which individuals can work together to build on their diverse strengths, delivering their personal best, and making significant contributions to worldwide communities.

MONOJO departments: scope of activities and services

The R&D and technical operations

MONOJO with its highly expert researchers and scientists in addition to the collaboration with the Institute of Biotechnology at the University of Cambridge has dedicated its research and development labs for transferring the promise at biotechnology into safe and effective innovative solutions and therapies, which will reflect major positive impacts on patients’ lives, worldwide environment, and economic well-being.

R&D main activities and services include

  • Discovering and manufacturing novel hybridomas and antibodies

  • Antimicrobial activity testing

  • Anticancer agents testing

  • QC for applications of biosimilars and bioproducts

  • ISO consultation

  1. Discovering and manufacturing novel hybridomas and antibodies

The MONOJO R&D team specializes in delivering antibodies based on genetic, peptide, and antigen approaches. Our experience includes designing immunogenic peptides and testing using specialized software.

MONOJO technology relies on advanced biotechnical equipment and experts on antibody technologies. We offer the world the right expertise, quality biotech therapies, and highly competitive prices.

  • R&D activities include

    • Antigen preparation

      • Peptide design

      • Protein extraction and purification

      • Peptide synthesis

    • Custom antibodies

      • Application guaranteed antibody (ELISA, Western Blot, and IHC)

    • Antibody purification

      • Affinity chromatography

      • Ion exchange and hydrophobic columns

    • Antibody identification

      • ELISA

      • Dot blot

      • Western blot

      • IHC (immunohistochemistry)

      • Flow cytometry

    • Antibody labeling service

      • HRP (horseradish peroxidase)

      • Biotin

    • The following Mabs are currently available upon request for research purposes

      • CK

      • PR

      • S100

  • Antibody activity testing

MONOJO is committed to investigating and performing antimicrobial susceptibility of natural and peptide compounds against a wide variety of human pathogens, we are dedicated to improving worldwide health and preventing diseases. Our microbiology lab follows CLSI recommendations and guidelines in determining the MIC of antimicrobial agent using standard microbroth dilution and agar diffusion methods.

R&D activities and services include

  1. Antimicrobial susceptibility testing

    • Standard zones of inhibition (Kerby Bauer method)

    • Determination of minimal inhibitory concentration (MIC)

    • Determination of minimal bactericidal concentration (MBC)

  2. Determination of antimicrobial resistance

    • MRSA (methicillin resistant S. aureus) screening

    • ESBL (extended spectrum beta lactamases) screening

    • MDROs (multidrug resistant organisms)

    • KPC (Klebsella Pneumoniae carbapenemase) producing organisms

  3. Antimicrobial technology screening

    • Bacteriostatic vs. bactericidal agents

    • Antifungal agents

  4. Disinfectant testing

    • Germicidal activity testing

    • Antifungal activity testing

  1. Anticancer agents testing

    MONOJO is committed to providing the facility to test and potentially design anticancer drugs and determine their effectiveness. Our specialists in association with our collaborators enable us to design optimal studies that provide in vitro and in vivo anticancer efficacy data for our clients in addition to regulatory applications.

  2. QC for application of biosimilars and bioproducts

    MONOJO provides consultation services for quality control (QC) and quality assurance (QA) for biosimilars in Jordan. We provide basic experiments for testing purity, identity, and integrity of biological products used in pharmaceutical and industrial applications. In addition, in cooperation with our international collaborators, we provide potential information about regulatory pathways and strategies for biosimilars.

  3. ISO consultation

    MONOJO also provides the appropriate training and consultation required to attain ISO/IEC 17025 and ISO 13485 for ISO certification. The company also prepares the required documentation, and establishes the quality assurance system with the overall quality manual in order to satisfy:

  1. Customers’ needs and expectations for ISO preparations

  2. The ISO certifications requirements

  3. The requirements of GLP (Good Laboratory Practices)

The Training Center

MONOJO is committed to providing premier training to attendees from academia, industry, medical settings, and government institutes. The company, provides specialist practical training to newcomers and non-specialist in multidisciplinary areas of biotechnology, clinical laboratory sciences, molecular identification of pathogens, biopharmaceutical quality control, and business development and marketing strategies. Also as regards ISO and GMP training and consultation, we can also design customized training courses tailored to your needs. Our courses usually consist of a mixture of lectures and practical training at MONOJO which is equipped with suitable lab instrumentation and skillful lab technicians. All delegates receive comprehensive training manuals, containing abstracts, lecture notes and guidelines for relevant laboratory procedures.

The collaborators consist of highly experienced senior life science and technology specialists who pocess the relevant management and line experience of multidisciplinary areas of life sciences, medicine, biotechnology and industry. Our lecturers and lab technicians have qualified educational background, PhDs, MScs and Bachelor biotechnologists, immunologists, microbiologists, chemists, pharmacists, economists in addition to many years on the job experience.

The unique combination of MONOJO team and collaborators adds extra value by bringing up diverse perspectives in order to bring innovation and novelty to our training programs.

  1. Courses topics which are covered by MONOJO

    • Molecular biotechnology

    • Applied immunology and immunoassays

    • Tissue culture and hybridoma technology

    • Basic and advanced real time PCR

    • Cytogenetics and molecular diagnostics

    • Pharmaceutical biotechnology and biosimilars

    • Medical and molecular microbiology

    • Proteomics

    • Quality control and quality management of medical laboratories

    • ISO 9001, 13485 and 17025 training

The Training Center

The MONOJO businesses are totally dedicated to work on the entire company vision and mission by translating them into corporate objectives, positioning, and marketing promotional strategies for MONOJO’s novel brand pipelines. The unit ensures the growth of MONOJO’s Biotech leadership position is enhanced by signing partnership and collaboration agreements based on innovative biotech projects, or on licensing of biotech brands for a selected region.

Our Partnering Opportunities

In order to maximize the value of our corporate mission, we consider our strategy mutually beneficial partnering and collaboration options:

  1. With applied biotech research institutes (companies or academic) :

    • MONOJO can support and facilitate collaborative biotech research and novel projects through the process of clients’ products development, and the process of new discovered innovation

    • MONOJO has the ability to implement and perform testing for biologicals and biosimilars therapies

    • MONOJO can facilitate the sharing of its expertise and knowledge to increase other institutes’ research capabilities through scientific visits and training for researchers either in-house or at their own institutes

  2. With other multinational biotech organizations:

    • MONOJO’s licensing strategy and knowledge in the field of biotechnology, and its strong staff expertise and presence within 18 MENA markets makes us an attractive partner for multinational biotech organizations seeking access and success within the region

Our current partnerships

I. Current partner: Institute of Biotechnology, University of Cambridge, UK

Product/project: MOU collaboration agreement for biotech research and projects

Established: 2009

URL: http://www.cam.ac.uk/

II. Current partner: Missouri Innovation Center (MIC), University of Missouri, Columbia, State of Missouri, USA

Product/project: Joint research project in biotechnology

Established: 2012

URL: http://www.missouri.edu/

III. Current partner: Infynity Biomarkers, France

Product/project: Collaboration agreement in cell lines biomarkers

Established: 2012

URL: http://www.infynity-biomarkers.com/

IV. Current partner: Hikma Pharmaceuticals PLC, Jordan

Product/project: R&D collaboration

Established: 2009.

URL: http://www.hikma.com/

V. Current partner: Labatec Pharma, Switzerland

Product/project: R&D collaboration

Established: 2009

URL: http://www.labatecpharma.com/

VI. Current partner: International Pharmaceutical Research Center (IPRC), Jordan

Product/project: Agreement of testing for IPRC bioproducts

Established: 2012

URL: http://www.iprc.com.jo/

Clinical trials

MONOJO is dedicated to develop, manufacture, and marketing newly innovative therapies to treat serious illnesses along with careful ethical procedures according to current international guidelines. One of these procedures is clinical trials.

MONOJO haing finished its preclinical trials is looking to begin clinical trial with the best CRO (Phase I, II and III) on volunteers (patients) in order to observe the effectiveness of its novel therapies on human subjests and their possible adverse side effects.

Corporate responsibility

The Applied Scientific Research Fund (ASRF) is a spin off non-profit organization from MONOJO, created and initially funded by Dr. Samih Darwazeh, the founder of Hikma Pharmaceuticals and chairman of MONOJO, to promote the development of applied science and engineering ideas. Our main target investigators are colleges and universities in many fields such as medicine, natural sciences, engineering, information technology and many others.

ASRF is the first research funding organization initiated from the private sector in Jordan as a non-profit company acting on a commercial basis while 100% of the profit is invested back in the fund to support the creation of the innovation ecosystem in Jordan and the Middle East. We at ASRF are applying and experimenting new innovation funding approaches in the Middle East while focusing on sustainability. ASRF will fund applied researches and innovations that have market potential and the return on investment will be through intellectual property commercialization.

URL: www.asrf.jo

Certificates

MONOJO has been approved by Lloyds Register Quality Assurance for the following Quality Management System Standards:

  • ISO 13485:2003

    • The quality management system is applicable to “Production of IVD’s: Antibodies”

  • ISO 9001: 2008

    • The quality management system is applicable to “Production of IVDs: antibodies and provision of practical biotech courses”

Board of directors

MONOJO’s board of directors brings together a group of highly experienced entrepreneurs, scientists and venture capital investment representatives.

  • Chairman: Dr. Samih Darwazeh

  • Vice Chairman: Dr. Marwan Kamal

  • Member: Prof. Chris Lowe

  • Member: Mrs. Penelope Shihab

  • Member: Dr. Feras Al-Alaaly

Management team

MONOJO’s team expertise brings together a wealth of multidisciplinary talent

  • CEO & Founder: Mrs. Penelope Shihab

  • The Financial & Administrative Manager: Mr. Sameer Nasrallah

  • R&D Manager: Dr. Khalid Al-Qaoud

  • Microbiology Section Head: Dr. Luay Abu Qatouseh

  • Training Manager: Mrs. Abeer Awad

  • Business Development Manager: Mr. Mohammad Abu-Zaid

Key investors

  • Dr. Samih Darwazeh

  • The Higher Council for Science and Technology – HCST

  • Royal Scientific Society – RSS

  • Jordan University for Science and Technology – JUST

  • Philadelphia University

  • Petra University

  • Al-Nahil Group

  • University of Jordan

  • Yarmouk University

National strategic alliance

  • Jordan University of Science and Technology

  • Yarmouk University

  • University of Jordan

  • Hashemite University

Locations and spin offs

  • Amman City, Jordan

    • THE MONOJO “Jordan Company for Antibody Production” (Head Quarter)

    • The Applied Scientific Research Fund – ASRF (Spin Off from MONOJO)

  • Columbia, MS, USA

    • COLUMBIA BIOTECH (US MONOJO’s Subsidiary)

    • Contact : Tel : +962 6 5161398

    •    +962 6 5155078

    •    +962 6 5155095

    •   Fax : +962 6 5161399

    •   P.O.Box 675 Al-Jubaiha 11941 Jordan

    •   E-mail:


Correpsonding author: Mohammad Z. Abu-Zaid, Business Development Department, MONOJO Biotech, Khalil Al Saket Street, Al Jubaiha, Amman 11941, Jordan

Published Online: 2013-08-09
Published in Print: 2013-03-01

©2013 by Walter de Gruyter Berlin Boston

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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