Startseite Synthesis of a sialic acid derivative of ristocetin aglycone as an inhibitor of influenza virus
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Synthesis of a sialic acid derivative of ristocetin aglycone as an inhibitor of influenza virus

  • Ilona Bakai-Bereczki EMAIL logo , Mihály Herczeg , Bernadett György , Lieve Naesens und Pál Herczegh
Veröffentlicht/Copyright: 15. Mai 2015
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Abstract

In order to promote attachment of the ristocetin aglycone molecule to the surface of the influenza virus, the aglycone was derivatized with a hemagglutinin ligand sialic acid moiety using a click reaction. The sialoristocetin derivative exhibited somewhat lower anti-influenza virus activity than ristocetin and aglycoristocetin.

References

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Received: 2014-9-30
Revised: 2015-2-18
Accepted: 2015-2-18
Published Online: 2015-5-15
Published in Print: 2015-8-1

© Institute of Chemistry, Slovak Academy of Sciences

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