β-Cyclodextrin as water-solubility enhancer for butylated hydroxytoluene
-
Marcin Lukasiewicz
,
Stanislaw Kowalski
Abstract
The phenomenon of the increase in solubility of the non-polar phenolic antioxidant - butylated hydroxytoluene (BHT) - in aqueous solutions containing β-cyclodextrin (CD) was studied. The complexation of BHT by CD was investigated using a phase solubility study. This method makes it possible to calculate the apparent formation constant for the host-guest complex. In addition, the thermodynamic properties were evaluated, revealing a spontaneous endothermic process of complex formation. Two solubility models were also used to verify their applicability to predicting the BHT concentration in solution. Those models included the modified Apelblat and Buchowski-Ksiazczak equations. In order to investigate the antioxidant properties of the BHT/CD/water ternary systems, a radical scavenging activity using a DPPH stable radical was performed. The experiments indicated that the antioxidant activity is temperature- and CD concentration-dependent. It was shown that complexation may inhibit the radical scavenging by BHT or change the scavenging stoichiometry.
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© 2015
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Articles in the same Issue
- Perovskite ceramics and recent experimental progress in reactor design for chemical looping combustion application
- Total reflection X-ray fluorescence analysis of fly ash from Bulgarian coal-fired power plants
- Ascorbic acid amperometric sensor using a graphene-wrapped hierarchical TiO2 nanocomposite
- Rapid determination of products of phenol hydrogenation in a supercritical water system using headspace gas chromatography
- Swelling of N-vinylcaprolactam–dodecyl methacrylate gel in {heptane + toluene} mixtures
- Extraction of Cu(II) with Acorga M5640 using hollow fibre liquid membrane
- Heat transfer in a jacketed agitated vessel equipped with multistage impellers
- Seasonal variation in alkaloid composition and antiproliferative activity of Stylophorum lasiocarpum (Oliv.) Fedde
- A polyacrylate prepared using polyurethane surfactants: properties of emulsion and film
- Efficient synthesis of glutaric acid from L-glutamic acid via diazoniation/hydrogenation sequence
- New insights into bromination process: effective preparation of Ambroxol
- A concise route to 4-aminomethylpyrazoles and 4-aminomethylisoxazoles from acetylacetone-derived hexahydropyrimidines under mild conditions
- Assessment of non-standard reaction conditions for asymmetric 1,3-dipolar organocatalytic cycloaddition of nitrone with α,β-unsaturated aldehydes
- β-Cyclodextrin as water-solubility enhancer for butylated hydroxytoluene
- Asymmetric polymerisation of substituted phenylacetylene using chiral Rh(2,5-norbornadiene)(L-proline) catalyst
