Startseite Cardiac troponin I release after a basketball match in elite, amateur and junior players
Artikel
Lizenziert
Nicht lizenziert Erfordert eine Authentifizierung

Cardiac troponin I release after a basketball match in elite, amateur and junior players

  • Isaac López-Laval , Alejandro Legaz-Arrese EMAIL logo , Keith George , Olga Serveto-Galindo , José María González-Rave , Joaquín Reverter-Masia und Diego Munguía-Izquierdo
Veröffentlicht/Copyright: 2. Juli 2015
Veröffentlichen auch Sie bei De Gruyter Brill
Manuskript einreichen Informationen für Autor*innen
Clinical Chemistry and Laboratory Medicine (CCLM)
Aus der Zeitschrift Clinical Chemistry and Laboratory Medicine (CCLM) Band 54 Heft 2

Abstract

Background: Available scientific data related to cardiac troponin I (cTnI) release after intermittent exercise is limited. It is also of interest to determine what personal or environmental factors mediate the exercise-induced release of cTnI. This study had two objectives: 1) to examine the individual release of cTnI to a basketball match; and 2) to establish the influence of athlete status as well as biological age on cTnI release.

Methods: Thirty-six basketball players (12 adult elite [PBA]: 27.3±4.1 years, 12 adult amateur [ABA]: 29.6±2.9 years, and 12 junior elite [JBA]: 16.6±0.9 years) participated in a simulated basketball match with serial assessment of cTnI at rest, immediately post- and at 1, 3, 6, 12, and 24 h post-exercise.

Results: The basketball match increased cTnI levels (pre: median [range]; 0.006 [0.001–0.026]; peak post: 0.024 [0.004–0.244] μg/L; p=0.000), with substantial individual variability in peak values. PBA and JBA players showed higher baseline and post-exercise cTnI values than ABA (all p<0.05). Peak cTnI exceeded the upper reference limit (URL) in the 26% of players (3 PBA; 6 JBA).

Conclusions: The current results suggest that intermittent exercise can promote the appearance of cTnI and that this is potentially mediated by athlete status.

Keywords: athlete status; biological age; cTnI; intermittent exercise
Corresponding author: Alejandro Legaz-Arrese, Departamento de Fisiatría y Enfermería. C/Domingo Miral S/N. 50009. Zaragoza, Spain, Phone: +34 976761000, Fax: +34 976761720, E-mail: ; and Section of Physical Education and Sports, University of Zaragoza, Zaragoza, Spain

Acknowledgments

The authors would like to thank all the participants for their participation in this study.

Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission. ALA, KG and DMI conception and design of research. ILL, OSG, JMGR and JRM performed experiments. ILL and DMI analyzed data. DMI prepared figures. ILL drafted manuscript. ALA, KG and DMI edited and revised manuscript. All authors read and approved the final manuscript.

Research funding: This study was supported by the DEP 2010-16767 grants from the Spanish Plan for Research, Development and Innovation (R+D+i) MICINN.

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

References

1. Scharhag J, George K, Shave R, Urhausen A, Kindermann W. Exercise-associated increases in cardiac biomarkers. Med Sci Sports Exer 2008;40:1408–15.10.1249/MSS.0b013e318172cf22Suche in Google Scholar PubMed

2. Shave R, Oxborough D. Exercise-induced cardiac injury: evidence from novel imaging techniques and highly sensitive cardiac troponin assays. Prog Cardiovasc Dis 2012;54:407–15.10.1016/j.pcad.2012.01.007Suche in Google Scholar PubMed

3. Serrano-Ostáriz E, Legaz-Arrese A, Terreros-Blanco JL, López-Ramón M, Cremades-Arroyos D, Carranza-García LE, et al. Cardiac biomarkers and exercise duration and intensity during a cycle-touring event. Clin J Sport Med 2009;19:293–9.10.1097/JSM.0b013e3181ab3c9dSuche in Google Scholar PubMed

4. Shave R, Ross P, Low D, George K, Gaze D. Cardiac troponin I is released following high-intensity short-duration exercise in healthy humans. Int J Cardiol 2010;145:337–9.10.1016/j.ijcard.2009.12.001Suche in Google Scholar PubMed

5. Serrano-Ostáriz E, Terreros-Blanco JL, Legaz-Arrese A, George K, Shave R, Bocos-Terraz P, et al. The impact of exercise duration and intensity on the release of cardiac biomarkers. Scand J Med Sci Sports 2011;21:244–9.10.1111/j.1600-0838.2009.01042.xSuche in Google Scholar PubMed

6. Eijsvogels T, George K, Shave R, Gaze D, Levine BD, Hopman MT, et al. Effect of prolonged walking on cardiac troponin levels. Am J Cardiol 2010;105:267–72.10.1016/j.amjcard.2009.08.679Suche in Google Scholar PubMed

7. Shave R, George KP, Atkinson G, Hart E, Middleton N, Whyte G, et al. Exercise-induced cardiac troponin T release: a meta-analysis. Med Sci Sports Exer 2007;39:2099–106.10.1249/mss.0b013e318153ff78Suche in Google Scholar PubMed

8. Neilan TG, Januzzi JL, Lee-Lewandrowski E, Ton-Nu TT, Yoerger DM, Jassal DS, et al. Myocardial injury and ventricular dysfunction related to training levels among nonelite participants in the Boston marathon. Circulation 2006;114:2325–33.10.1161/CIRCULATIONAHA.106.647461Suche in Google Scholar PubMed

9. Tian Y, Nie J, Huang C, George KP. The kinetics of highly sensitive cardiac troponin T release after prolonged treadmill exercise in adolescent and adult athletes. J Appl Physiol 2012;113:418–25.10.1152/japplphysiol.00247.2012Suche in Google Scholar PubMed

10. Carranza-García LE, George K, Serrano-Ostáriz E, Casado-Arroyo R, Caballero-Navarro AL, Legaz-Arrese A. Cardiac biomarker response to intermittent exercise bouts. Int J Sports Med 2011;32:327–31.10.1055/s-0030-1263138Suche in Google Scholar PubMed

11. Rahnama N, Faramarzi M, Gaeini AA. Effects of intermittent exercise on cardiac troponin I and creatine kinase-MB. Int J Prev Med 2011;2:20–3.Suche in Google Scholar

12. George KP, Dawson E, Shave RE, Whyte G, Jones M, Hare E, et al. Left ventricular systolic function and diastolic filling after intermittent high intensity team sports. Br J Sports Med 2004;38:452–6.10.1136/bjsm.2003.004788Suche in Google Scholar PubMed PubMed Central

13. Nie J, Tong TK, Shi Q, Lin H, Zhao J, Tian Y. Serum cardiac troponin response in adolescents playing basketball. Int J Sports Med 2008;29:449–52.10.1055/s-2007-989236Suche in Google Scholar PubMed

14. Wedin JO, Henriksson AE. Postgame elevation of cardiac markers among elite floorball players. Scand J Med Sci Sports 2014. [Epub ahead of print 2014 Aug 11]. doi:10.1111/sms.12304.10.1111/sms.12304Suche in Google Scholar PubMed

15. Fortescue EB, Shin AY, Greenes DS, Mannix RC, Agarwal S, Feldman BJ, et al. Cardiac troponin increases among runners in the Boston Marathon. Ann Emerg Med 2007;49:137–43.10.1016/j.annemergmed.2006.09.024Suche in Google Scholar PubMed

16. Mehta R, Gaze D, Mohan S, Williams KL, Sprung V, George K, et al. Post-exercise cardiac troponin release is related to exercise training history. Int J Sports Med 2012;33:333–7.10.1055/s-0031-1301322Suche in Google Scholar PubMed

17. Mingels A, Jacobs L, Michielsen E, Swaanenburg J, Wodzig W, van Dieijen-Visser M. Reference population and marathon runner sera assessed by highly sensitive cardiac troponin T and commercial cardiac troponin T and I assays. Clin Chem 2009;55:101–8.10.1373/clinchem.2008.106427Suche in Google Scholar PubMed

18. Nie J, George KP, Tong TK, Gaze D, Tian Y, Lin H, et al. The influence of a half-marathon race upon cardiac troponin T release in adolescent runners. Curr Med Chem 2011;18:3452–6.10.2174/092986711796642625Suche in Google Scholar PubMed

19. Tian Y, Nie J, Tong TK, Cao J, Gao Q, Man J, et al. Changes in serum cardiac troponins following a 21-km run in junior male runners. J Sports Med Phys Fitness 2006;46:481–8.Suche in Google Scholar

20. Middleton N, George K, Whyte G, Gaze D, Collinson P, Shave R. Cardiac troponin T release is stimulated by endurance exercise in healthy humans. J Am Coll Cardiol 2008;52:1813–4.10.1016/j.jacc.2008.03.069Suche in Google Scholar PubMed

21. Bonetti A, Tirelli F, Albertini R, Monica C, Monica M, Tredici G. Serum cardiac troponin T after repeated endurance exercise events. Int J Sports Med 1996;17:259–62.10.1055/s-2007-972843Suche in Google Scholar PubMed

22. König D, Schumacher YO, Heinrich L, Schmid A, Berg A, Dickhuth HH. Myocardial stress after competitive exercise in professional road cyclists. Med Sci Sports Exer 2003;35:1679–83.10.1249/01.MSS.0000089248.37173.E7Suche in Google Scholar PubMed

23. Legaz-Arrese A, López-Laval I, George K, Puente-Lanzarote JJ, Mayolas-Pi C, Serrano-Ostáriz E, et al. Impact of an endurance training program on exercise-induced cardiac biomarker release. Am J Physiol Heart Circ Physiol 2015;308:H913–20.10.1152/ajpheart.00914.2014Suche in Google Scholar

24. Fu F, Nie J, George K, Tom TK, Lin H, Shi Q. Impact of 21-km run on cardiac biomarkers in adolescent runners. J Exerc Sci Fit 2010;8:61–6.10.1016/S1728-869X(10)60009-3Suche in Google Scholar

25. Nie J, Tong TK, George K, Fu FH, Lin H, Shi Q. Resting and post-exercise serum biomarkers of cardiac and skeletal muscle damage in adolescent runners. Scand J Med Sci Sports 2011;21:625–9.10.1111/j.1600-0838.2010.01096.xSuche in Google Scholar PubMed

26. Léger L, Gadoury C. Validity of the 20 m shuttle run test with 1 min stages to predict VO2max in adults. Can J Sport Sci 1989;14:21–6.Suche in Google Scholar

27. Eggers KM, Lagerqvist B, Venge P, Wallentin L, Lindahl B. Persistent cardiac troponin I elevation in stabilized patients after an episode of acute coronary syndrome predicts long-term mortality. Circulation 2007;116:1907–14.10.1161/CIRCULATIONAHA.107.708529Suche in Google Scholar PubMed

28. Fu F, Nie J, Tong TK. Serum cardiac troponin T in adolescent runners: effects of exercise intensity and duration. Int J Sports Med 2009;30:168–72.10.1055/s-0028-1104586Suche in Google Scholar PubMed

29. Tian Y, Nie J, George KP, Huang C. Reproducibility of cardiac biomarkers response to prolonged treadmill exercise. Biomarkers 2014;19:114–20.10.3109/1354750X.2014.880855Suche in Google Scholar PubMed

30. Saravia SG, Knebel F, Schroeckh S, Ziebig R, Lun A, Weimann A, et al. Cardiac troponin T release and inflammation demonstrated in marathon runners. Clin Lab 2010;56:51–8.Suche in Google Scholar

31. Klinkenberg LJ, Res PT, van Loon LJ, van Dieijen-Visser MP, Meex SJ. Strong link between basal and exercise-induced cardiac troponin T levels: do both reflect risk? Int J Cardiol 2012;158:129–31.10.1016/j.ijcard.2012.04.050Suche in Google Scholar PubMed

32. Legaz-Arrese A, George K, Carranza-García LE, Munguía-Izquierdo D, Moros-García T, Serrano-Ostáriz E. The impact of exercise intensity on the release of cardiac biomarkers in marathon runners. Eur J Appl Physiol 2011;111:2961–7.10.1007/s00421-011-1922-3Suche in Google Scholar PubMed

33. Legaz-Arrese A, González-Carretero M, Lacambra-Blasco I. Adaptation of left ventricular morphology to long-term training in sprint- and endurance-trained elite runners. Eur J Appl Physiol 2006;96:740–6.10.1007/s00421-005-0076-6Suche in Google Scholar PubMed

34. Legaz Arrese A, Serrano Ostáriz E, González Carretero M, Lacambra Blasco I. Echocardiography to measure fitness of elite runners. J Am Soc Echocardiog 2005;18:419–26.10.1016/j.echo.2005.02.002Suche in Google Scholar PubMed

Received: 2015-4-5
Accepted: 2015-6-8
Published Online: 2015-7-2
Published in Print: 2016-2-1

©2016 by De Gruyter

Artikel in diesem Heft

  1. Frontmatter
  2. Editorial
  3. Total error vs. measurement uncertainty: the match continues
  4. Review
  5. Application of fatty acid and lipid measurements in neuropsychiatry
  6. Mini Review
  7. The Janus faces of acquired angioedema: C1-inhibitor deficiency, lymphoproliferation and autoimmunity
  8. Opinion Papers
  9. How to report results of prothrombin and activated partial thromboplastin times
  10. Useful measures and models for analytical quality management in medical laboratories
  11. Total error vs. measurement uncertainty: revolution or evolution?
  12. Genetics and Molecular Diagnostics
  13. Rapid detection of Mmalton α1-antitrypsin deficiency allele by real-time PCR and melting curves in whole blood, serum and dried blood spot samples
  14. General Clinical Chemistry and Laboratory Medicine
  15. Diagnostic and clinical significance of Crohn’s disease-specific pancreatic anti-GP2 and anti-CUZD1 antibodies
  16. Immunoassays for the detection of IgA antibodies to tissue transglutaminase: significance of multiples of the upper limit of normal and inter-assay correlations
  17. Effects of biobanking conditions on six antibiotic substances in human serum assessed by a novel evaluation protocol
  18. Haematology and Coagulation
  19. Measurement of dabigatran, rivaroxaban and apixaban in samples of plasma, serum and urine, under real life conditions. An international study
  20. Reference Values and Biological Variations
  21. Upper reference limits for cerebrospinal fluid total protein and albumin quotient based on a large cohort of control patients: implications for increased clinical specificity
  22. Reference intervals for bone turnover markers in Spanish premenopausal women
  23. Cancer Diagnostics
  24. Citrulline as a biomarker of gastrointestinal toxicity in patients with rectal carcinoma treated with chemoradiation
  25. mRNA overexpression of kallikrein-related peptidase 14 (KLK14) is an independent predictor of poor overall survival in chronic lymphocytic leukemia patients
  26. Cardiovascular Diseases
  27. TBX20 loss-of-function mutation associated with familial dilated cardiomyopathy
  28. Cardiac troponin I release after a basketball match in elite, amateur and junior players
  29. The role of timely measurement of galectin-3, NT-proBNP, cystatin C and hsTnT in predicting prognosis and heart function after heart transplantation
  30. Infectious Diseases
  31. Neutrophil CD64 combined with PCT, CRP and WBC improves the sensitivity for the early diagnosis of neonatal sepsis
  32. A comparison of three commercial platforms for urinary NGAL in critically ill adults
  33. Diabetes
  34. Liquid citrate acidification introduces significant glucose bias and leads to misclassification of patients with diabetes
  35. Letter to the Editors
  36. A rare and unstable hemoglobin variant, Hb M Dothan β 25/26 (-GTG), detected by the anomalous cytogram on Sysmex XE-2100
  37. Hb Hope [β136Gly→Asp] and Hb Grady [α119_120insGluPheThr] compound heterozygosity in a Mauritanian patient
  38. Falsely elevated ferritin in patients with a high concentration of rheumatoid factor
  39. Susceptibility of commonly used ferritin assays to the classic hook effect
  40. Comparison of the Elecsys calcitonin assay with the Immulite 1000 assay. Describing one case with heterophilic antibody interference
  41. Performance evaluation of low platelet count and platelet clumps detection on Mindray BC-6800 hematology analyzer
  42. Fetal sex discordance between sequencing-based and real-time PCR non-invasive prenatal test due to a vanishing twin
  43. Total HIV-1 DNA detection and quantification in peripheral blood by COBAS®AmpliPrep/COBAS® TaqMan® HIV-1 Test, v2.0
  44. A replacement for the testosterone “sex gap”
  45. Added value of indirect immunofluorescence intensity of automated antinuclear antibody testing in a secondary hospital setting
https://doi.org/10.1515/cclm-2015-0304
Schlagwörter für diesen Artikel
athlete status; biological age; cTnI; intermittent exercise

Artikel in diesem Heft

  1. Frontmatter
  2. Editorial
  3. Total error vs. measurement uncertainty: the match continues
  4. Review
  5. Application of fatty acid and lipid measurements in neuropsychiatry
  6. Mini Review
  7. The Janus faces of acquired angioedema: C1-inhibitor deficiency, lymphoproliferation and autoimmunity
  8. Opinion Papers
  9. How to report results of prothrombin and activated partial thromboplastin times
  10. Useful measures and models for analytical quality management in medical laboratories
  11. Total error vs. measurement uncertainty: revolution or evolution?
  12. Genetics and Molecular Diagnostics
  13. Rapid detection of Mmalton α1-antitrypsin deficiency allele by real-time PCR and melting curves in whole blood, serum and dried blood spot samples
  14. General Clinical Chemistry and Laboratory Medicine
  15. Diagnostic and clinical significance of Crohn’s disease-specific pancreatic anti-GP2 and anti-CUZD1 antibodies
  16. Immunoassays for the detection of IgA antibodies to tissue transglutaminase: significance of multiples of the upper limit of normal and inter-assay correlations
  17. Effects of biobanking conditions on six antibiotic substances in human serum assessed by a novel evaluation protocol
  18. Haematology and Coagulation
  19. Measurement of dabigatran, rivaroxaban and apixaban in samples of plasma, serum and urine, under real life conditions. An international study
  20. Reference Values and Biological Variations
  21. Upper reference limits for cerebrospinal fluid total protein and albumin quotient based on a large cohort of control patients: implications for increased clinical specificity
  22. Reference intervals for bone turnover markers in Spanish premenopausal women
  23. Cancer Diagnostics
  24. Citrulline as a biomarker of gastrointestinal toxicity in patients with rectal carcinoma treated with chemoradiation
  25. mRNA overexpression of kallikrein-related peptidase 14 (KLK14) is an independent predictor of poor overall survival in chronic lymphocytic leukemia patients
  26. Cardiovascular Diseases
  27. TBX20 loss-of-function mutation associated with familial dilated cardiomyopathy
  28. Cardiac troponin I release after a basketball match in elite, amateur and junior players
  29. The role of timely measurement of galectin-3, NT-proBNP, cystatin C and hsTnT in predicting prognosis and heart function after heart transplantation
  30. Infectious Diseases
  31. Neutrophil CD64 combined with PCT, CRP and WBC improves the sensitivity for the early diagnosis of neonatal sepsis
  32. A comparison of three commercial platforms for urinary NGAL in critically ill adults
  33. Diabetes
  34. Liquid citrate acidification introduces significant glucose bias and leads to misclassification of patients with diabetes
  35. Letter to the Editors
  36. A rare and unstable hemoglobin variant, Hb M Dothan β 25/26 (-GTG), detected by the anomalous cytogram on Sysmex XE-2100
  37. Hb Hope [β136Gly→Asp] and Hb Grady [α119_120insGluPheThr] compound heterozygosity in a Mauritanian patient
  38. Falsely elevated ferritin in patients with a high concentration of rheumatoid factor
  39. Susceptibility of commonly used ferritin assays to the classic hook effect
  40. Comparison of the Elecsys calcitonin assay with the Immulite 1000 assay. Describing one case with heterophilic antibody interference
  41. Performance evaluation of low platelet count and platelet clumps detection on Mindray BC-6800 hematology analyzer
  42. Fetal sex discordance between sequencing-based and real-time PCR non-invasive prenatal test due to a vanishing twin
  43. Total HIV-1 DNA detection and quantification in peripheral blood by COBAS®AmpliPrep/COBAS® TaqMan® HIV-1 Test, v2.0
  44. A replacement for the testosterone “sex gap”
  45. Added value of indirect immunofluorescence intensity of automated antinuclear antibody testing in a secondary hospital setting
Jetzt anmelden und 20% sparen
Institutioneller Zugang
Wie funktioniert Authentifizierung?
Haben Sie eine Idee, wie wir unsere Website verbessern können?
Bitte schreiben Sie uns.
© 2025 De Gruyter Brill
Heruntergeladen am 19.9.2025 von https://www.degruyterbrill.com/document/doi/10.1515/cclm-2015-0304/html
Button zum nach oben scrollen