Fetal and neonatal outcome in patients with anterior abdominal wall defects (gastroschisis and omphalocele)
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Ingolf Juhasz-Böss
,
Rangmar Goelz
Abstract
Fetuses with gastroschisis and omphalocele frequently show intrauterine growth restriction (IUGR). The aim of our study was to evaluate the intrauterine course of IUGR and the neonatal outcome in a large patient collective. We retrospectively included all euploid fetuses with gastroschisis and omphalocele between 2001 and 2009 in a single tertiary center. Patients’ characteristics, serial ultrasound examinations and neonatal outcomes were evaluated. From 39 fetuses (28 gastroschisis, 11 omphalocele) 61.5% had IUGR <5th percentile and 15.4% had IUGR<10th percentile. The rate of IUGR did not differ significantly between the two groups during pregnancy. Newborns with gastroschisis showed an average weight of 2386 g, and those with omphalocele showed an average weight of 3148 g (P<0.001). Nevertheless, newborns with omphalocele were more frequently eutrophic than those with gastroschisis (88.8% vs. 52.2%, P=0.079). On average, only one surgical intervention was necessary for the definitive repair of the defect (65.5% of the newborns). Children with gastroschisis remained hospitalized nearly twice as long as children with an omphalocele (38 vs. 20 days). IUGR rates during pregnancy did not differ significantly between fetuses with gastroschisis and omphalocele although patients with defects of omphalocele were more frequently eutrophic at birth. Most newborns needed only one operation for definitive surgical treatment. The mean hospitalization time after this intervention was 4 weeks.
©2012 by Walter de Gruyter Berlin Boston
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Articles in the same Issue
- Review article
- WAPM Working Group on Nutrition: Potential chronobiotic role of human milk in sleep regulation
- Opinion Paper
- “Every case of asphyxia can be used as a learning example”. Conclusions from an analysis of substandard obstetrical care
- Original Articles – Obstetrics
- Hematologic profile of the fetus with systemic inflammatory response syndrome
- Optimized amniotic fluid analysis in patients suspected of intrauterine infection/inflammation
- Risk factors for preterm delivery with placenta previa
- Recombinant human factor VIIa prevents hysterectomy in severe postpartum hemorrhage: single center study
- Combination antiretroviral therapy with protease inhibitors in HIV-infected pregnancy
- Vitamin D status during normal pregnancy and postpartum. A longitudinal study in 141 Danish women
- The impact of the time interval between two successive deliveries in an obstetric unit in terms of the mode of each delivery and the rate of perinatal mortality
- Original Articles – Fetus
- Terbutaline: effects on the fetal heart at term
- Parallel maternal and fetal immune activation by bacterial toxins in vitro
- Original Articles – Newborn
- Prepregnancy body mass index, socioeconomic status, race/ethnicity and breastfeeding practices
- Fetal and neonatal outcome in patients with anterior abdominal wall defects (gastroschisis and omphalocele)
- Total serum bilirubin level in umbilical cord blood and respiratory distress syndrome in very low birth weight infants
- Short Communication
- Improved overall delivery documentation following implementation of a standardized shoulder dystocia delivery form
- Letters to the Editor
- Prevention of prematurity – a complex undertaking
- Prevention of prematurity – a complex undertaking reply
- Congress calendar
- 10.1515/JPM-2011-1000
