Article
Licensed
Unlicensed
Requires Authentication
Parallel maternal and fetal immune activation by bacterial toxins in vitro
-
Bruce K. Young
,
Xiao Li
Published/Copyright:
August 12, 2011
Abstract
This study evaluated in vitro immune responses to Escherichia coli lipopolysaccharide in maternal and fetal blood. Samples were concurrently obtained from maternal venipuncture and umbilical cord blood samples and cultured with the E. coli endotoxin, and cytokines were assayed. There were statistically significant correlations between maternal and fetal samples. This demonstrates maternal and fetal immune communication and mutual programming during pregnancy. Subclinical infection, which predisposes to premature labor, could be detectable from a maternal blood sample even if derived only from the fetal compartment. A maternal blood panel test might serve as a diagnostic screen for subclinical infection in patients at risk for preterm labor.
Received: 2011-6-27
Accepted: 2011-6-30
Published Online: 2011-08-12
Published in Print: 2012-01-01
©2012 by Walter de Gruyter Berlin Boston
You are currently not able to access this content.
You are currently not able to access this content.
Articles in the same Issue
- Review article
- WAPM Working Group on Nutrition: Potential chronobiotic role of human milk in sleep regulation
- Opinion Paper
- “Every case of asphyxia can be used as a learning example”. Conclusions from an analysis of substandard obstetrical care
- Original Articles – Obstetrics
- Hematologic profile of the fetus with systemic inflammatory response syndrome
- Optimized amniotic fluid analysis in patients suspected of intrauterine infection/inflammation
- Risk factors for preterm delivery with placenta previa
- Recombinant human factor VIIa prevents hysterectomy in severe postpartum hemorrhage: single center study
- Combination antiretroviral therapy with protease inhibitors in HIV-infected pregnancy
- Vitamin D status during normal pregnancy and postpartum. A longitudinal study in 141 Danish women
- The impact of the time interval between two successive deliveries in an obstetric unit in terms of the mode of each delivery and the rate of perinatal mortality
- Original Articles – Fetus
- Terbutaline: effects on the fetal heart at term
- Parallel maternal and fetal immune activation by bacterial toxins in vitro
- Original Articles – Newborn
- Prepregnancy body mass index, socioeconomic status, race/ethnicity and breastfeeding practices
- Fetal and neonatal outcome in patients with anterior abdominal wall defects (gastroschisis and omphalocele)
- Total serum bilirubin level in umbilical cord blood and respiratory distress syndrome in very low birth weight infants
- Short Communication
- Improved overall delivery documentation following implementation of a standardized shoulder dystocia delivery form
- Letters to the Editor
- Prevention of prematurity – a complex undertaking
- Prevention of prematurity – a complex undertaking reply
- Congress calendar
- 10.1515/JPM-2011-1000
Articles in the same Issue
- Review article
- WAPM Working Group on Nutrition: Potential chronobiotic role of human milk in sleep regulation
- Opinion Paper
- “Every case of asphyxia can be used as a learning example”. Conclusions from an analysis of substandard obstetrical care
- Original Articles – Obstetrics
- Hematologic profile of the fetus with systemic inflammatory response syndrome
- Optimized amniotic fluid analysis in patients suspected of intrauterine infection/inflammation
- Risk factors for preterm delivery with placenta previa
- Recombinant human factor VIIa prevents hysterectomy in severe postpartum hemorrhage: single center study
- Combination antiretroviral therapy with protease inhibitors in HIV-infected pregnancy
- Vitamin D status during normal pregnancy and postpartum. A longitudinal study in 141 Danish women
- The impact of the time interval between two successive deliveries in an obstetric unit in terms of the mode of each delivery and the rate of perinatal mortality
- Original Articles – Fetus
- Terbutaline: effects on the fetal heart at term
- Parallel maternal and fetal immune activation by bacterial toxins in vitro
- Original Articles – Newborn
- Prepregnancy body mass index, socioeconomic status, race/ethnicity and breastfeeding practices
- Fetal and neonatal outcome in patients with anterior abdominal wall defects (gastroschisis and omphalocele)
- Total serum bilirubin level in umbilical cord blood and respiratory distress syndrome in very low birth weight infants
- Short Communication
- Improved overall delivery documentation following implementation of a standardized shoulder dystocia delivery form
- Letters to the Editor
- Prevention of prematurity – a complex undertaking
- Prevention of prematurity – a complex undertaking reply
- Congress calendar
- 10.1515/JPM-2011-1000
