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National screening program vs. standardized neurodevelopmental follow-up
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Cornelia Maschke
Veröffentlicht/Copyright:
1. September 2008
Abstract
Background: Long-term follow-up is urgently needed to decide on the consequences of new therapies.
Objective: This study assesses the use of a national child development screening program for a follow-up examination of a defined patient group.
Patients and methods: Neurodevelopmental outcome of 139 survivors after intrauterine laser coagulation for severe twin-twin transfusion syndrome was investigated both according to a standardized neurodevelopmental follow-up and according to the pediatricians' screening examinations.
Results: Screening and standardized tests revealed identical results in 90.6% of the cases. Using the national screening program only four out of 139 children (2.9%) with minor neurological disabilities would have been missed. For identifying mild or severe neurodevelopmental abnormalities the screening has a sensivity of 78% and a specifity of 93%. The positive predictive value is 61% and the negative predictive value 97%.
Conclusions: The use of already available and established follow-up programs for extended follow-up studies would considerably reduce costs, time and manpower.
Keywords: Laser coagulation; neurodevelopmental follow-up; preterm infant; screening examinations; twin-twin transfusion syndrome
Received: 2008-1-15
Revised: 2008-6-11
Accepted: 2008-7-30
Published Online: 2008-09-01
Published Online: 2008-9-1
Published in Print: 2009-01-01
©2009 by Walter de Gruyter Berlin New York
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Schlagwörter für diesen Artikel
Laser coagulation;
neurodevelopmental follow-up;
preterm infant;
screening examinations;
twin-twin transfusion syndrome
Artikel in diesem Heft
- Recommendations and guidelines for perinatal practice
- Perinatal echocardiography: protocols for evaluating the fetal and neonatal heart
- Review article
- Progestational agents for the prevention of preterm birth
- Original articles – Obstetrics
- High cytomegalovirus IgG avidity is a reliable indicator of past infection in patients with positive IgM detected during the first trimester of pregnancy
- Erythrocyte changes in preeclampsia: relationship between maternal and cord blood erythrocyte damage
- Amniotic fluid adhesion molecules during parturition at term
- Serum levels of adenosine deaminase and pregnancy-related hormones in hyperemesis gravidarum
- Association between von Willebrand factor gene polymorphism and preeclampsia
- The effect of the 2004 Italian legislation on perinatal outcomes following assisted reproduction technology
- Original article – Fetus
- Growth deficit in term small-for-gestational fetuses with normal umbilical artery Doppler is associated with adverse outcome
- Evidence to support that spontaneous preterm labor is adaptive in nature: neonatal RDS is more common in “indicated” than in “spontaneous” preterm birth
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