Sequela of preterm versus term infants born to mothers on a methadone maintenance program: differential course of neonatal abstinence syndrome
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Kevin Dysart
Abstract
Objective: We determined the effect of preterm delivery on the course of neonatal abstinence syndrome (NAS) in infants born to mothers participating in a methadone maintenance program.
Study design: A retrospective cohort study was conducted in which infant and maternal data were collected from the medical records of 53 preterm and 66 term infants. Infants were selected from all infants admitted to Thomas Jefferson University hospital born between 1998 and 2002 whose mothers were enrolled in the methadone maintenance program. All infants were managed by a standard protocol utilizing the Neonatal Abstinence Scoring System (NASS) and neonatal opiate solution (NOS). Preterm and term infants were compared.
Results: Preterm infants had shorter lengths of stay, treatment courses and required less medication than did term infants during the same time period.
Conclusion: These data indicate that following exposure to maternal methadone, preterm infants have a different neonatal course than do infants born at term.
©2007 by Walter de Gruyter Berlin New York
Articles in the same Issue
- WAPM-Newsletter No 1/2007 8th WORLD CONGRESS OF PERINATAL MEDICINE in Florence, Italy, September 9–13, 2007
- Poverty and perinatal health
- Maternal mortality in Africa
- Lessons learned from four advanced abdominal pregnancies at an East African Health Center
- Incidence and correlates of cesarean section in a capital city of a middle-income country
- Metabolic changes, hypothalamo-pituitary-adrenal axis and oxidative stress after short-term starvation in healthy pregnant women
- Does maternal docosahexaenoic acid supplementation during pregnancy and lactation lower BMI in late infancy?
- Feasibility of a randomized controlled trial testing nifedipine vs. placebo for the treatment of preterm labor
- Atosiban versus usual care for the management of preterm labor
- Umbilical cord blood collection: do patients really understand?
- Comparison between singleton- and triplet-specific “growth” curves to detect growth restricted triplet infants
- Role of visfatin, insulin-like growth factor-I and insulin in fetal growth
- Dynamic QT/RR relationship of cardiac conduction in premature infants treated with low-dose doxapram hydrochloride
- Risk factors and outcomes for ventilator-associated pneumonia in neonatal intensive care unit patients
- Neonatal outcomes in triplet pregnancies: assisted reproduction versus spontaneous conception
- Sequela of preterm versus term infants born to mothers on a methadone maintenance program: differential course of neonatal abstinence syndrome
- Vacuum extraction and autonomic balance in human infants
- Accuracy of second trimester fetal head circumference and biparietal diameter for predicting the time of spontaneous birth
- Reply
- Induction of labor with oral misoprostol for premature rupture of membranes at term in women with unfavorable cervix
- Reply
- In memoriam: Prof. Shouichi Sakamoto
- Congress Calendar
Articles in the same Issue
- WAPM-Newsletter No 1/2007 8th WORLD CONGRESS OF PERINATAL MEDICINE in Florence, Italy, September 9–13, 2007
- Poverty and perinatal health
- Maternal mortality in Africa
- Lessons learned from four advanced abdominal pregnancies at an East African Health Center
- Incidence and correlates of cesarean section in a capital city of a middle-income country
- Metabolic changes, hypothalamo-pituitary-adrenal axis and oxidative stress after short-term starvation in healthy pregnant women
- Does maternal docosahexaenoic acid supplementation during pregnancy and lactation lower BMI in late infancy?
- Feasibility of a randomized controlled trial testing nifedipine vs. placebo for the treatment of preterm labor
- Atosiban versus usual care for the management of preterm labor
- Umbilical cord blood collection: do patients really understand?
- Comparison between singleton- and triplet-specific “growth” curves to detect growth restricted triplet infants
- Role of visfatin, insulin-like growth factor-I and insulin in fetal growth
- Dynamic QT/RR relationship of cardiac conduction in premature infants treated with low-dose doxapram hydrochloride
- Risk factors and outcomes for ventilator-associated pneumonia in neonatal intensive care unit patients
- Neonatal outcomes in triplet pregnancies: assisted reproduction versus spontaneous conception
- Sequela of preterm versus term infants born to mothers on a methadone maintenance program: differential course of neonatal abstinence syndrome
- Vacuum extraction and autonomic balance in human infants
- Accuracy of second trimester fetal head circumference and biparietal diameter for predicting the time of spontaneous birth
- Reply
- Induction of labor with oral misoprostol for premature rupture of membranes at term in women with unfavorable cervix
- Reply
- In memoriam: Prof. Shouichi Sakamoto
- Congress Calendar
