Long-term subcutaneous morphine administration after surgery in newborns
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Kerstin Rouss
Abstract
Aim: To analyze the management of newborns after major surgery receiving morphine subcutaneously and to identify possible side effects.
Methods: Morphine was administered via a subcutaneous catheter (Insuflon®) in 20 newborns after major surgery. Side effects like hypotension, pain during morphine administration and local infection were noted. Morphine dose was adjusted according to the hospital guidelines with the Neonatal Infant Pain Score (NIPS) and the Finnegan withdrawal score.
Results: Surgery was performed at the median age of 38 5/7 weeks (range: 32 1/7–49 5/7 weeks). Before starting subcutaneous morphine administration, patients received intravenous morphine for a median of two weeks (range six days to seven weeks). All patients showed good pain relief with no severe side effects. Three patients reacted with crying to the first dose of subcutaneous morphine. No other side effects occurred.
Conclusion: Subcutaneous application of morphine with the Insuflon® catheter is an alternative to intravenous treatment of postoperative pain in neonates. In this small group pain relief was good and side effects were harmless.
References
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©2007 by Walter de Gruyter Berlin New York
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- Examining the relationship between positive mid-gestational fetal fibronectin assays and histological evidence of acute placental inflammation
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- Gender- and parity-specific reference charts for fetal size in low risk singleton pregnancies at the onset of the third trimester
- Near term twin pregnancy: clinical relevance of weight discordance at birth
- Intracerebellar hemorrhage in premature infants: sonographic detection and outcome
- Determining the least time required for measuring energy expenditure in premature neonates
- Neither maternal nor fetal mutation (E474Q) in the α-subunit of the trifunctional protein is frequent in pregnancies complicated by HELLP syndrome
- Long-term subcutaneous morphine administration after surgery in newborns
- Superior sagittal sinus thrombosis: a rare but serious complication of hypernatremic dehydration in newborns
- Congress Calendar
- Roster of Perinatal Societies
Articles in the same Issue
- Cervical surgery and preterm birth
- How useful is 3D and 4D ultrasound in perinatal medicine?
- The combined effect of maternal smoking and obesity on the risk of preeclampsia
- Slow change in body mass index during early triplet pregnancy is associated with decreased birth weight
- Examining the relationship between positive mid-gestational fetal fibronectin assays and histological evidence of acute placental inflammation
- Paternal smoking is associated with a decreased prevalence of type 1 diabetes mellitus among offspring in two national British birth cohort studies (NCDS and BCS70)
- Three-dimensional ultrasound power Doppler assessment of the cervix: comparison between nulliparas and multiparas
- Gender- and parity-specific reference charts for fetal size in low risk singleton pregnancies at the onset of the third trimester
- Near term twin pregnancy: clinical relevance of weight discordance at birth
- Intracerebellar hemorrhage in premature infants: sonographic detection and outcome
- Determining the least time required for measuring energy expenditure in premature neonates
- Neither maternal nor fetal mutation (E474Q) in the α-subunit of the trifunctional protein is frequent in pregnancies complicated by HELLP syndrome
- Long-term subcutaneous morphine administration after surgery in newborns
- Superior sagittal sinus thrombosis: a rare but serious complication of hypernatremic dehydration in newborns
- Congress Calendar
- Roster of Perinatal Societies
