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Fetal growth restriction associated with measles virus infection during pregnancy

  • Kosuke Kobayashi , Makiko Tajima , Satoshi Toishi , Ken Fujimori , Yoshio Suzuki and Hideo Udagawa
Published/Copyright: June 1, 2005
Journal of Perinatal Medicine
From the journal Volume 33 Issue 1

Abstract

We report on a 28-week infant with growth restriction starting after 23 weeks' gestation because of measles virus (MV) infection of the mother. Histological findings for the placenta revealed extensive fibrin deposition and necrosis of the villi, and MV antigen was demonstrated in the syncytiotrophoblast by immunostaining. The MV-specific IgM level in the infant was negative, but that of the mother was positive. Therefore, we speculate that growth restriction is not attributed to direct infection with MV, but to placental dysfunction due to a decrease in intravillous blood flow and oxygen supply to the fetus.

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Corresponding author: Kosuke Kobayashi, M.D., Asahi General Hospital, Dept. of Obstetrics Gynecology, Asahi-shi, I-1326, Chiba, 285-2511/Japan.

References

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Published Online: 2005-06-01
Published in Print: 2005-01-01

©2005 by Walter de Gruyter Berlin New York

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