Comparison of perinatal outcome in fetuses with reverse or absent enddiastolic flow in the umbilical artery and/or fetal descending aorta
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A. K. Ertan
Abstract
Objectives: To examine the differences of perinatal outcome in fetuses with absent and reversed enddiastolic flow velocity waveforms of the umbilical artery or fetal descending aorta.
Design: In a retrospective study, 30 pregnant women with reversed enddiastolic flow in the umbilical artery or fetal aorta (group I) were compared with 30 cases of absent enddiastolic flow (group II). Patients were included in the groups according to the last Doppler finding before delivery. Perinatal and neonatal outcome was correlated with antenatal Doppler flow findings.
Results: The mean gestational age at birth was 31 weeks in both groups. Fetuses with reverse flow showed higher perinatal (27% and 7% respectively) and overall mortality (53.3% and 10% respectively) compared to the absent enddiastolic flow group (p < 0.05). All the intrauterine fetal deaths occurred in the reversed flow group (n = 12). The rates of intrauterine growth retardation, oligohydramnios and hypocalcemia were different between the groups (p < 0.05). The cesarean section rate, perinatal and neonatal complications including the incidence of acidosis, the number of cases admitted to neonatal intensive care unit and mean treatment time were not different between the groups. A tendency to higher incidence of neonatal cerebral hemorrhage in reversed flow cases (28%) compared to absent enddiastolic flow cases (17%) was observed, but this was not statistically significant.
Conclusions: The present study suggests that reversed flow should be seen as a particular clinical entity with higher incidences of perinatal and overall mortality, and severe intrauterine growth retardation (< 5. perc) compared to the absent enddiastolic flow group. The optimal timing of delivery in pregnancies complicated by highly pathological Doppler flow findings is only to be resolved in well-designed randomized, multicenter clinical trials.
Copyright © 2003 by Walter de Gruyter GmbH & Co. KG
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Articles in the same Issue
- Bioelectrical impedance analysis in the clinical management of preeclamptic women with edema
- Decreasing resistance in the maternal uterine and peripheral arterial system is apparently unrelated to plasma and urinary levels of nitrite/nitrate and cyclic-guanosinmonophosohate during the course of normal pregnancies
- Inducing proliferation of human amnion epithelial and mesenchymal cells for prospective engineering of membrane repair
- Obstetric outcome of excessively overgrown fetuses (≥= 5000 g): a case-control study
- Computerized analysis of fetal heart rate indices during oral glucose tolerance test
- Comparison of perinatal outcome in fetuses with reverse or absent enddiastolic flow in the umbilical artery and/or fetal descending aorta
- Operative fetoscopical management of intrauterine obstructive uropathia by urethral stent
- The impact of intrapartum factors on umbilical cord blood stem cell banking
- Neonatal nucleated red blood cell count and postpartum complications in growth restricted fetuses
- Neonatal outcome of growth discordant twin gestations
- Management of unscarred ruptured uterus
- Lethargy in a newborn: lithium toxicity or lab error?
- Acute ethanol intoxication during pregnancy and consecutive fetal cardiac arrest: a case report
- Acute pancreatitis occurring in the early postpartum period: a case report
- Book Review
- Congress Calendar
