Sequential use of thrombolytic agents for thrombosed mitral valve prosthesis during pregnancy
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A. H. Nassar
Abstract
Thrombolytic therapy has gained popularity as an alternative to surgery in the treatment of prosthetic heart valve thrombosis.We report on the sequential use of streptokinase followed by recombinant tissue type plasminogen activator (rt-PA) for the treatment of a thrombosed prosthetic mitral valve in a pregnant woman at 26 weeks of gestation. Although thrombolysis was unsuccessful, the patient carried till 34 weeks of gestation and delivered by cesarean section a live newborn with an uneventful postpartum course. Based on our case and on what has been previously described in the literature, thrombolytic therapy should be considered as an option in the management of hemodynamically unstable pregnant patients with prosthetic valve thrombosis.When a single agent proves insufficient, combination therapy should be considered as it might provide hemodynamic stability and improvement in cardiac function that would allow patients at a high surgical risk to carry their pregnancy to viability.
Copyright © 2003 by Walter de Gruyter GmbH & Co. KG
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- Congress Calendar
Articles in the same Issue
- Telemedicine for antenatal surveillance of high-risk pregnancies with ambulatory and home fetal heart rate monitoring – an update
- The HELLP-syndrome; maternal-fetal outcome and follow up of infants
- Effect of maternal age on blood loss during parturition: a retrospective multivariate analysis of 10,053 cases
- Prenatal medicine related to stress and depressive reactions of pregnant women and their partners
- Accuracy of sonographic estimation of fetal weight before induction of labor in diabetic pregnancies and pregnancies with suspected fetal macrosomia
- Validity of short term variation (STV) in detection of fetal acidemia
- Amikacin alters auditory brainstem conduction time in newborns
- Triplets and quadruplets in Switzerland: comparison with singletons, and evolution over the last decade
- Maternal smoking during pregnancy and appetite control in offspring
- Sequential use of thrombolytic agents for thrombosed mitral valve prosthesis during pregnancy
- Congenital mixed malignant germ cell tumor involving cerebrum and orbit
- Jejunal atresia related to the use of toluidine blue in genetic amniocentesis in twins
- Congress Calendar
