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The HELLP-syndrome; maternal-fetal outcome and follow up of infants

  • A. C. Roelofsen , M. G. van Pampus and J. G. Aarnoudse
Published/Copyright: June 1, 2005
Journal of Perinatal Medicine
From the journal Volume 31 Issue 3

Abstract

Objective: To investigate maternal-fetal outcome of infants born after pregnancies complicated by (H)ELLP syndrome. Study design: A retrospective cohort study was performed on patients with the HELLP or ELLP syndrome. Maternal and perinatal complications were recorded. The follow-up period of the infants was at least 18 months. A multivariate regression analysis was done to define the variables mostly contributing to adverse outcome. Results: No maternal deaths occurred. Eighteen infants of the HELLP group and six infants of the ELLP group died; total perinatal mortality was 17.6%. After 18 months four infants had major handicaps, making a total adverse outcome of 22.8%. Statistical analysis shows early gestational age, prolongation of pregnancy and administration of antihypertensive medication as the factors influencing outcome of the infants most. Conclusions: Prolongation of pregnancy contributed to better perinatal outcome, while administration of antihypertensive medication and early gestational age were related to a more unfavorable outcome.

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Published Online: 2005-06-01
Published in Print: 2003-05-14

Copyright © 2003 by Walter de Gruyter GmbH & Co. KG

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