Detection of directed information flow in biosignals
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Matthias Winterhalder
Abstract
Several analysis techniques have been developed for time series to detect interactions in multidimensional dynamic systems. When analyzing biosignals generated by unknown dynamic systems, awareness of the different concepts upon which these analysis techniques are based, as well as the particular aspects the methods focus on, is a basic requirement for drawing reliable conclusions. For this purpose, we compare four different techniques for linear time series analysis. In general, these techniques detect the presence of interactions, as well as the directions of information flow, in a multidimensional system. We review the different conceptual properties of partial coherence, a Granger causality index, directed transfer function, and partial directed coherence. The performance of these tools is demonstrated by application to linear dynamic systems.
References
1 Baccala LA, Sameshima K. Partial directed coherence: a new concept in neural structure determination. Biol Cybern2001; 84: 463–474.10.1007/PL00007990Search in Google Scholar
2 Brillinger DR. Time series: Data analysis and theory. San Francisco: Holden-Day Inc 1981.10.2307/2530198Search in Google Scholar
3 Granger J. Investigating causal relations by econometric models and cross-spectral methods. Econometrica1969; 37: 424–438.10.2307/1912791Search in Google Scholar
4 Hellwig B, Häußler S, Schelter B, et al. Tremor correlated cortical activity in essential tremor. Lancet2001; 357: 519–523.10.1016/S0140-6736(00)04044-7Search in Google Scholar
5 Hesse W, Möller E, Arnold M, Schack B. The use of time-variant EEG Granger causality for inspecting directed interdependencies of neural assemblies. J Neurosci Methods2003; 124: 27–44.10.1016/S0165-0270(02)00366-7Search in Google Scholar
6 Kamiński MJ, Blinowska KJ, Szelenberger W. Topographic analysis of coherence and propagation of EEG activity during sleep and wakefulness. Electroencephalogr Clin Neurophysiol1997; 102: 216–227.10.1016/S0013-4694(96)95721-5Search in Google Scholar
7 Möller E, Schack B, Arnold M, Witte H. Instantaneous multivariate EEG coherence analysis by means of adaptive high-dimensional autoregressive models. J Neurosci Methods2001; 105: 143–158.10.1016/S0165-0270(00)00350-2Search in Google Scholar
8 Mormann F, Lehnertz K, David P, Elger CE. Mean phase coherence as a measure for phase synchronization and its application to the EEG of epilepsy patients. Physica D2000; 144: 358–369.10.1016/S0167-2789(00)00087-7Search in Google Scholar
9 Schelter B, Winterhalder M, Eichler M, et al. Testing for directed influences among neural signals using partial directed coherence. J Neurosci Methods2006; 152: 210–219.10.1016/j.jneumeth.2005.09.001Search in Google Scholar PubMed
10 Stam CJ. Nonlinear dynamical analysis of EEG and MEG: Review of an emerging field. Clin Neurophysiol2005; 116: 2266–2301.10.1016/j.clinph.2005.06.011Search in Google Scholar PubMed
11 Tass P, Rosenblum MG, Weule J, et al. Detection of n:m phase locking from noisy data: application to magnetoencephalography. Phys Rev Lett1998; 81: 3291–3295.10.1103/PhysRevLett.81.3291Search in Google Scholar
12 Timmer J, Lauk M, Häußler S, et al. Cross-spectral analysis of tremor time series. Int J Bifurc Chaos2000; 10: 2595–2610.10.1142/S0218127400001663Search in Google Scholar
13 Varela F, Lachaux JP, Rodriguez E, Martinerie J. The brain web: Phase synchronization and large-scale integration. Nat Rev Neurosci2001; 2: 229–239.10.1038/35067550Search in Google Scholar PubMed
14 Winterhalder M, Schelter B, Hesse W, et al. Comparison of time series analysis techniques to detect direct and time-varying interrelations in multivariate, neural systems. Signal Process2005; 85: 2137–2160.10.1016/j.sigpro.2005.07.011Search in Google Scholar
©2006 by Walter de Gruyter Berlin New York
Articles in the same Issue
- Biosignal Processing: various concepts, various applications – but a common drive
- Detection of directed information flow in biosignals
- Data mining in medical time series
- State-space analysis of joint angle kinematics in normal treadmill walking
- From diagnostics to therapy – conceptual basis for real-time movement feedback in rehabilitation medicine
- Investigations of back muscle fatigue by simultaneous 31P MRS and surface EMG measurements
- Application of EMG signals for controlling exoskeleton robots
- Processing of physiological signals in automotive research
- Tracer kinetic analysis of signal time series from dynamic contrast-enhanced MR imaging
- A fiber optic sensor system for control of rate-adaptive cardiac pacemakers and implantable defibrillators / Ein faseroptisches Sensorsystem zur Steuerung von frequenzadaptiven Herzschrittmachern und implantierbaren Defibrillatoren
- Investigation of the influence of blood flow rate on large vessel cooling in hepatic radiofrequency ablation / Untersuchung des Einflusses der Blutflussgeschwindigkeit auf die Gefäßkühlung bei der Radiofrequenzablation von Lebertumoren
- Determination of oxygen saturation and hematocrit of flowing human blood using two different spectrally resolving sensors / Bestimmung von Sauerstoffsättigung und Hämatokrit an fließendem Blut mit zwei verschiedenen spektralen Sensoren
- Karl Fischer titration and coulometry for measurement of water content in small cartilage specimens / Bestimmung des Wassergehalts in kleinen Knorpelproben durch Karl-Fischer-Titration und Coulometrie
- Synergistic effects of mixed TiAlV and polyethylene wear particles on TNFα response in THP-1 macrophages / Synergistische Effekte gemischter TiAlV- und Polyethylen-Abriebpartikel auf die TNFα-Antwort in THP-1 Makrophagen
- FE-Simulation zur Lokalisierung hoch beanspruchter Bereiche in der Hüftpfanne von Endoprothesen / FE-analysis of surface stresses for the tribological system in total hip prostheses
- Partial hemi-resurfacing of the hip joint – a new approach to treat local osteochondral defects? / Gelenkoberflächen-Teilersatz am Hüftgelenk – ein neuer Ansatz zur Behandlung osteochondraler Defekte?
- Stellungnahme zu „Der Einfluss von Laserlichtbestrahlung niedriger Leistungsdichte auf einen experimentellen Knorpelschaden im Kniegelenk des Kaninchens: eine in vivo-Untersuchung unter Berücksichtigung makroskopischer, histologischer und immunhistochemischer Veränderungen”; Biomed Tech 2006; 51: 131–138
- Contents index volume 51 (2006)
- Author index volume 51 (2006)
Articles in the same Issue
- Biosignal Processing: various concepts, various applications – but a common drive
- Detection of directed information flow in biosignals
- Data mining in medical time series
- State-space analysis of joint angle kinematics in normal treadmill walking
- From diagnostics to therapy – conceptual basis for real-time movement feedback in rehabilitation medicine
- Investigations of back muscle fatigue by simultaneous 31P MRS and surface EMG measurements
- Application of EMG signals for controlling exoskeleton robots
- Processing of physiological signals in automotive research
- Tracer kinetic analysis of signal time series from dynamic contrast-enhanced MR imaging
- A fiber optic sensor system for control of rate-adaptive cardiac pacemakers and implantable defibrillators / Ein faseroptisches Sensorsystem zur Steuerung von frequenzadaptiven Herzschrittmachern und implantierbaren Defibrillatoren
- Investigation of the influence of blood flow rate on large vessel cooling in hepatic radiofrequency ablation / Untersuchung des Einflusses der Blutflussgeschwindigkeit auf die Gefäßkühlung bei der Radiofrequenzablation von Lebertumoren
- Determination of oxygen saturation and hematocrit of flowing human blood using two different spectrally resolving sensors / Bestimmung von Sauerstoffsättigung und Hämatokrit an fließendem Blut mit zwei verschiedenen spektralen Sensoren
- Karl Fischer titration and coulometry for measurement of water content in small cartilage specimens / Bestimmung des Wassergehalts in kleinen Knorpelproben durch Karl-Fischer-Titration und Coulometrie
- Synergistic effects of mixed TiAlV and polyethylene wear particles on TNFα response in THP-1 macrophages / Synergistische Effekte gemischter TiAlV- und Polyethylen-Abriebpartikel auf die TNFα-Antwort in THP-1 Makrophagen
- FE-Simulation zur Lokalisierung hoch beanspruchter Bereiche in der Hüftpfanne von Endoprothesen / FE-analysis of surface stresses for the tribological system in total hip prostheses
- Partial hemi-resurfacing of the hip joint – a new approach to treat local osteochondral defects? / Gelenkoberflächen-Teilersatz am Hüftgelenk – ein neuer Ansatz zur Behandlung osteochondraler Defekte?
- Stellungnahme zu „Der Einfluss von Laserlichtbestrahlung niedriger Leistungsdichte auf einen experimentellen Knorpelschaden im Kniegelenk des Kaninchens: eine in vivo-Untersuchung unter Berücksichtigung makroskopischer, histologischer und immunhistochemischer Veränderungen”; Biomed Tech 2006; 51: 131–138
- Contents index volume 51 (2006)
- Author index volume 51 (2006)
