Increased local levels of granulocyte colony-stimulating factor are associated with the beneficial effect of pre-elafin (SKALP/trappin-2/WAP3) in experimental emphysema

References

Barnes, P.J. (2003). New concepts in chronic obstructive pulmonary disease. Annu. Rev. Med.54, 113–129.10.1146/annurev.med.54.101601.152209Search in Google Scholar

Barnes, P.J. (2004a). Alveolar macrophages in chronic obstructive pulmonary disease (COPD). Cell. Mol. Biol. (Noisy-le-grand) 50 Online Publication, OL627–OL637.Search in Google Scholar

Barnes, P.J. (2004b). COPD: is there light at the end of the tunnel? Curr. Opin. Pharmacol.4, 263–272.10.1016/j.coph.2004.03.001Search in Google Scholar

Barnes, P.J. (2004c). Mediators of chronic obstructive pulmonary disease. Pharmacol. Rev.56, 515–548.10.1124/pr.56.4.2Search in Google Scholar

Bingle, L., Tetley, T.D., and Bingle, C.D. (2001). Cytokine-mediated induction of the human elafin gene in pulmonary epithelial cells is regulated by nuclear factor-κB. Am. J. Respir. Cell Mol. Biol.25, 84–91.10.1165/ajrcmb.25.1.4341Search in Google Scholar

Boneberg, E.-M. and Hartung, T. (2002). Molecular aspects of anti-inflammatory action of G-CSF. Inflamm. Res.51, 119–128.10.1007/PL00000283Search in Google Scholar

Bourbonnais, Y., Larouche, C., and Tremblay, G.M. (2000). Production of full-length human pre-elafin, an elastase specific inhibitor, from yeast requires the absence of a functional Yapsin 1 (Yps1p) endoprotease. Protein Expr. Purif.20, 485–491.10.1006/prep.2000.1338Search in Google Scholar

Calverley, P.M.A. and Walker, P. (2003). Chronic obstructive pulmonary disease. Lancet362, 1053–1061.10.1016/S0140-6736(03)14416-9Search in Google Scholar

Donnelly, L.E. and Rogers, D.F. (2003). Therapy for chronic obstructive pulmonary disease in the 21st century. Drugs63, 1973–1998.10.2165/00003495-200363190-00002Search in Google Scholar PubMed

Dunnill, M.S. (1962). Quantitative methods in the study of pulmonary pathology. Thorax17, 320–328.10.1136/thx.17.4.320Search in Google Scholar PubMed PubMed Central

El Ouriaghli, F., Fujiwara, H., Melenhorst, J.J., Sconocchia, G., Hensel, N., and Barrett, A.J. (2003). Neutrophil elastase enzymatically antagonizes the in vitro action of G-CSF: implications for the regulation of granulopoiesis. Blood101, 1752–1758.10.1182/blood-2002-06-1734Search in Google Scholar PubMed

Hareng, L. and Hartung, T. (2002). Induction and regulation of endogenous granulocyte colony-stimulating factor formation. Biol. Chem.383, 1501–1517.10.1515/BC.2002.172Search in Google Scholar

Hirche, T.O., Atkinson, J.J., Bahr, S., and Belaaouaj, A. (2004). Deficiency in neutrophil elastase does not impair neutrophil recruitment to inflamed sites. Am. J. Respir. Cell Mol. Biol.30, 576–584.10.1165/rcmb.2003-0253OCSearch in Google Scholar

Ishizawa, K., Kubo, H., Yamada, M., Kobayashi, S., Numasaki, M., Ueda, S., Suzuki, T., and Sasaki, H. (2004). Bone marrow-derived cells contribute to lung regeneration after elastase-induced pulmonary emphysema. FEBS Lett.556, 249–252.10.1016/S0014-5793(03)01399-1Search in Google Scholar

Ito, S., Ingenito, E.P., Brewer, K.K., Black, L.D., Parameswaran, H., Lutchen, K.R., and Suki, B. (2005). Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model of emphysema: possible role of collagen remodeling. J. Appl. Physiol.98, 503–511.10.1152/japplphysiol.00590.2004Search in Google Scholar PubMed

Jian, M.-Y., Koizumi, T., Tsushima, K., Fujimoto, K., and Kubo, K. (2004). Effects of granulocyte colony-stimulating factor (G-CSF) and neutrophil elastase inhibitor (ONO-5046) on acid-induced lung injury in rats. Inflammation28, 327–336.10.1007/s10753-004-6643-xSearch in Google Scholar PubMed

Koyama, S., Sato, E., Masubuchi, T., Takamizawa, A., Kubo, K., Nagai, S., and Izumi, T. (1998). Alveolar type II-like cells release G-CSF as neutrophil chemotactic activity. Am. J. Physiol.275, L687–L693.10.1152/ajplung.1998.275.4.L687Search in Google Scholar PubMed

Kuraki, T., Ishibashi, M., Takayama, M., Shiraishi, M., and Yoshida, M. (2002). A novel oral neutrophil elastase inhibitor (ONO-6818) inhibits human neutrophil elastase-induced emphysema in rats. Am. J. Respir. Crit. Care Med.166, 496–500.10.1164/rccm.2103118Search in Google Scholar PubMed

Lucey, E.C., Keane, J., Kuang, P.-P., Snider, G.L., and Goldstein, R.H. (2002). Severity of elastase-induced emphysema is decreased in tumor necrosis factor-α and interleukin-1β receptor-deficient mice. Lab. Invest.82, 79–85.10.1038/labinvest.3780397Search in Google Scholar PubMed

Lundblad, L.K.A., Thompson-Figueroa, J., Leclair, T., Sullivan, M.J., Poynter, M.E., Irvin, C.G., and Bates, J.H.T. (2005). Tumor necrosis factor-α overexpression in lung disease: a single cause behind a complex phenotype. Am. J. Respir. Crit. Care Med.171, 1363–1370.10.1164/rccm.200410-1349OCSearch in Google Scholar PubMed PubMed Central

Lyerla, T.A., Rusiniak, M.E., Borchers, M., Jahreis, G., Tan, J., Ohtake, P., Novak, E.K., and Swank, R.T. (2003). Aberrant lung structure, composition, and function in a murine model of Hermansky-Pudlak syndrome. Am. J. Physiol.285, L643–L653.10.1152/ajplung.00024.2003Search in Google Scholar PubMed

Molhuizen, H.O.F. and Schalkwijk, J. (1995). Structural, biochemical, and cell biological aspects of the serine proteinase inhibitor SKALP/elafin/ESI. Biol. Chem. Hoppe-Seyler376, 1–7.Search in Google Scholar

Nara, K., Ito, S., Ito, T., Suzuki, Y., Ghoneim, M.A., Tachibana, S., and Hirose, S. (1994). Elastase inhibitor elafin is a new type of a proteinase inhibitor which has a transglutaminase-mediated anchoring sequence termed ‘cementoin’. J. Biochem.115, 441–448.10.1093/oxfordjournals.jbchem.a124357Search in Google Scholar

Nénan, S., Boichot, E., Lagente, V., and Bertrand, C.P. (2005). Macrophage elastase (MMP-12): a pro-inflammatory mediator? Mem. Inst. Oswaldo Cruz100 (Suppl. 1), 167–172.10.1590/S0074-02762005000900028Search in Google Scholar

Ohta, K., Nakajima, T., Cheah, A.Y.L., Zaidi, S.H.E., Kaviani, N., Dawood, F., You, X.-M., Liu, P., Husain, M., and Rabinovitch, M. (2004). Elafin-overexpressing mice have improved cardiac function after myocardial infarction. Am. J. Physiol.287, H286–H292.10.1152/ajpheart.00479.2002Search in Google Scholar

Sakai, H., Ingenito, E.P., Mora, R., Abbay, S., Cavalcante, F.S.A., Lutchen, K.R., and Suki, B. (2001). Hysteresivity of the lung and tissue strip in the normal rat: effects of heterogeneities. J. Appl. Physiol.91, 737–747.10.1152/jappl.2001.91.2.737Search in Google Scholar

Sano, C., Shimizu, T., Sato, K., Kawauchi, H., and Tomioka, H. (2000). Effects of secretory leucocyte protease inhibitor on the production of the anti-inflammatory cytokines, IL-10 and transforming growth factor-β (TGF-β), by lipopolysaccharide-stimulated macrophages. Clin. Exp. Immunol.121, 77–85.Search in Google Scholar

Schalkwijk, J., Wiedow, O., and Hirose, S. (1999). The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core. Biochem. J.340, 569–577.10.1042/bj3400569Search in Google Scholar

Schuessler, T.F. and Bates, J.H.T. (1995). A computer-controlled research ventilator for small animals: design and evaluation. IEEE Trans. Biomed. Eng.42, 860–866.10.1109/10.412653Search in Google Scholar

Shapiro, S.D. (2005). COPD unwound. N. Engl. J. Med.352, 2016–2019.10.1056/NEJMe058044Search in Google Scholar

Shapiro, S.D., Goldstein, N.M., Houghton, A.M., Kobayashi, D.K., Kelley, D., and Belaaouaj, A. (2003). Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice. Am. J. Pathol.163, 2329–2335.10.1016/S0002-9440(10)63589-4Search in Google Scholar

Soskel, N.T., Watanabe, S., Hardie, R., Shenvi, A.B., Punt, J.A., and Kettner, C. (1986). Effects of dosage and timing of administration of a peptide boronic acid inhibitor on lung mechanics and morphometrics in elastase-induced emphysema in hamsters. Am. Rev. Respir. Dis.133, 635–638.Search in Google Scholar

Spurzem, J.R. and Rennard, S.I. (2005). Pathogenesis of COPD. Sem. Respir. Crit. Care Med.26, 142–153.10.1055/s-2005-869535Search in Google Scholar PubMed

Steel, R.G.D. and Torrie, J.H. (1980). Principles and Procedures of Statistics. A Biometrical Approach (New York, USA: McGraw-Hill).Search in Google Scholar

Stockley, R.A. (2002). Neutrophils and the pathogenesis of COPD. Chest121, 151S–155S.10.1378/chest.121.5_suppl.151SSearch in Google Scholar PubMed

Stolk, J., Rudolphus, A., Davies, P., Osinga, D., Dijkman, J.H., Agarwal, L., Keenan, K.P., Fletcher, D., and Kramps, J.A. (1992). Induction of emphysema and bronchial mucus cell hyperplasia by intratracheal instillation of lipopolysaccharide in the hamster. J. Pathol.167, 349–356.10.1002/path.1711670314Search in Google Scholar

Tanaka, H., Nishino, M., Nakamori, Y., Ogura, H., Ishikawa, K., Shimazu, T., and Sugimoto, H. (2001). Granulocyte colony-stimulating factor (G-CSF) stiffens leukocytes but attenuates inflammatory response without lung injury in septic patients. J. Trauma51, 1110–1116.10.1097/00005373-200112000-00016Search in Google Scholar

Tazi, A., Nioche, S., Chastre, J., Smiéjan, J.-M., and Hance, A.J. (1991). Spontaneous release of granulocyte colony-stimulating factor (G-CSF) by alveolar macrophages in the course of bacterial pneumonia and sarcoidosis: endotoxin-dependent and endotoxin-independent G-CSF release by cells recovered by bronchoalveolar lavage. Am. J. Respir. Cell Mol. Biol.4, 140–147.10.1165/ajrcmb/4.2.140Search in Google Scholar

Tessier, P.A., Naccache, P.H., Diener, K.R., Gladue, R.P., Neote, K.S., Clark-Lewis, I., and McColl, S.R. (1998). Induction of acute inflammation in vivo by staphylococcal superantigens. II. Critical role for chemokines, ICAM-1, and TNF-α. J. Immunol.161, 1204–1211.Search in Google Scholar

Thébaud, B., Dansereau, A., Ladha, F., Bonnet, S., Sawicka, M., Bourbonnais, Y., Eaton, F., and Tremblay, G. (2005). Pre-elafin, a natural elastase inhibitor, prevents oxygen-induced lung injury in experimental bronchopulmonary dysplasia (BPD) [Abstract]. Proc. Am. Thorac. Soc.2, A24.Search in Google Scholar

Tremblay, G.M., Vachon, E., Larouche, C., and Bourbonnais, Y. (2002). Inhibition of human neutrophil elastase-induced acute lung injury in hamsters by recombinant human pre-elafin (trappin-2). Chest121, 582–588.10.1378/chest.121.2.582Search in Google Scholar

Tremblay, G.M., Janelle, M.F., and Bourbonnais, Y. (2003). Anti-inflammatory activity of neutrophil elastase inhibitors. Curr. Opin. Invest. Drugs4, 556–565.Search in Google Scholar

Tuder, R.M., McGrath, S., and Neptune, E. (2003). The pathobiological mechanisms of emphysema models: what do they have in common? Pulm. Pharmacol. Ther.16, 67–78.10.1016/S1094-5539(02)00099-8Search in Google Scholar

Vachon, E., Bourbonnais, Y., Bingle, C.D., Rowe, S.J., Janelle, M.F., and Tremblay, G.M. (2002). Anti-inflammatory effect of pre-elafin in lipopolysaccharide-induced acute lung inflammation. Biol. Chem.383, 1249–1256.10.1515/BC.2002.138Search in Google Scholar PubMed

Van de Kerkhof, P.C.M., Kuppens, L.H.C.M., Van Vlijmen, Y., and Schalkwijk, J. (1991). Distribution of skin-derived antileucoproteases (SKALP) in the marginal zone of the spreading psoriatic lesion. Br. J. Dermatol.124, 10–12.10.1111/j.1365-2133.1991.tb03275.xSearch in Google Scholar PubMed

van Eeden, S.F., Lawrence, E., Sato, Y., Kitagawa, Y., and Hogg, J.C. (2000). Neutrophils released from the bone marrow by granulocyte colony-stimulating factor sequester in lung microvessels but are slow to migrate. Eur. Respir. J.15, 1079–1086.10.1034/j.1399-3003.2000.01516.xSearch in Google Scholar PubMed

Zaidi, S.H.E., You, X.-M., Ciura, S., O'Blenes, S., Husain, M., and Rabinovitch, M. (2000). Suppressed smooth muscle proliferation and inflammatory cell invasion after arterial injury in elafin-overexpressing mice. J. Clin. Invest.105, 1687–1695.10.1172/JCI9147Search in Google Scholar PubMed PubMed Central