Identification of three novel mutations in the dihydropyrimidine dehydrogenase gene associated with altered pre-mRNA splicing or protein function

Articles in the same Issue

1. Highlight: Radicals in Enzymatic Catalysis
2. Radical-mediated dehydration reactions in anaerobic bacteria
3. Heterodisulfide reductase from methanogenic archaea: a new catalytic role for an iron-sulfur cluster
4. Structural and functional comparison of HemN to other radical SAM enzymes
5. New glycyl radical enzymes catalysing key metabolic steps in anaerobic bacteria
6. Unusual reactions involved in anaerobic metabolism of phenolic compounds
7. Novel bacterial molybdenum and tungsten enzymes: three-dimensional structure, spectroscopy, and reaction mechanism
8. Spectroscopic and theoretical approaches for studying radical reactions in class I ribonucleotide reductase
9. Biomimetic metal-radical reactivity: aerial oxidation of alcohols, amines, aminophenols and catechols catalyzed by transition metal complexes
10. Combinatorial approaches to functional models for galactose oxidase
11. Spectroscopic characterization of the iron-oxo intermediate in cytochrome P450
12. Impact of Mycoplasma hyorhinis infection on l-arginine metabolism: differential regulation of the human and murine iNOS gene
13. Degradation of the sodium taurocholate cotransporting polypeptide (NTCP) by the ubiquitin-proteasome system
14. Identification of three novel mutations in the dihydropyrimidine dehydrogenase gene associated with altered pre-mRNA splicing or protein function