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Combined transport of water and ions through membrane channels

  • Peter Pohl
Published/Copyright: June 1, 2005
Biological Chemistry
From the journal Volume 385 Issue 10

Abstract

The coupling of ion and water flow through membrane channels is under dispute. Among all human aquaporins only aquaporin-6 exhibits ion channel activity. Whether aquaporin-6 functions also as a water channel cannot yet be determined with confidence. Similarly, a comparison of single-channel water permeabilities from ion channels and aquaporins suggests that ion channels may play a secondary role as water channels. However, the fraction of absorbed fluid that crosses epithelial ion channels still remains to be determined.

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Published Online: 2005-06-01
Published in Print: 2004-10-01

© Walter de Gruyter

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