Mapping molecular landscapes inside cells
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Wolfgang Baumeister
Abstract
Cryoelectron tomography opens a window into the inner space of cells. It combines the potential of three-dimensional imaging with a close-to-life preservation of biological samples. Tomograms with molecular resolution are essentially images of the cellular proteome and, in conjunction with advanced pattern recognition techniques, they can be used to map the molecular landscape inside organelles and cells.
References
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© Walter de Gruyter
Artikel in diesem Heft
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- Generation of glycogen- and albumin-producing hepatocyte-like cells from embryonic stem cells
- Imaging morphological details and pathological differences of red blood cells using tapping-mode AFM
- A database search for double-strand containing RNAs in Dictyostelium discoideum
- Segregation of partly melted molecules: isolation of CpG islands by polyacrylamide gel electrophoresis
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Artikel in diesem Heft
- Wolfgang Baumeister – Felix Hoppe-Seyler Lecturer 2004
- Mapping molecular landscapes inside cells
- Paper of the Year 2003: Award to Dieter Hoffmann
- Structural basis of denitrification
- Roles of nectins in cell adhesion, migration and polarization
- Designing novel spectral classes of proteins with a tryptophan-expanded genetic code
- Imprinted small RNA genes
- Inter- and intra-molecular distances determined by EPR spectroscopy and site-directed spin labeling reveal protein-protein and protein-oligonucleotide interaction
- Combined transport of water and ions through membrane channels
- How do ABC transporters drive transport?
- X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880
- Generation of glycogen- and albumin-producing hepatocyte-like cells from embryonic stem cells
- Imaging morphological details and pathological differences of red blood cells using tapping-mode AFM
- A database search for double-strand containing RNAs in Dictyostelium discoideum
- Segregation of partly melted molecules: isolation of CpG islands by polyacrylamide gel electrophoresis
- A monomeric mutant of restriction endonuclease EcoRI nicks DNA without sequence specificity