5 MOF: an emerging material for biomedical applications
-
Rana Rashad Mahmood Khan
Abstract
Metal-organic frameworks (MOFs) have evolved into a large family of crystalline structures with extraordinarily high permeability and internal areas. Different forms of MOFs that connect with organic can be utilized as a medium for the covalent adhesion of particular substances that operate as receptors or increase chemicals in bioimaging applications. In water vapor, the MOF degradation process may be seen as a series of substitution processes in which hydroxide is replaced by metals-coordinated linkers. The temperature of the reaction is one of the most important aspects in the synthesis of MOFs, and there are typically two temperature varieties recognized: solvothermal and nonsolvothermal. Temperature changes in the reaction have a significant impact on the formation of products as well as the shape of crystals, resulting in denser structures being created at higher temperatures. We applied sophisticated methods for fabricating MOFs with medicines for biological purposes. MOF nanocarriers have been shown to achieve drug delivery and controlled drug release in recent studies, making them a promising class for drug delivery, including anticancer drugs, metabolic labeling molecules. MOFs have been exploited for imaging distinction and molecular therapies in preliminary biological applications.
Abstract
Metal-organic frameworks (MOFs) have evolved into a large family of crystalline structures with extraordinarily high permeability and internal areas. Different forms of MOFs that connect with organic can be utilized as a medium for the covalent adhesion of particular substances that operate as receptors or increase chemicals in bioimaging applications. In water vapor, the MOF degradation process may be seen as a series of substitution processes in which hydroxide is replaced by metals-coordinated linkers. The temperature of the reaction is one of the most important aspects in the synthesis of MOFs, and there are typically two temperature varieties recognized: solvothermal and nonsolvothermal. Temperature changes in the reaction have a significant impact on the formation of products as well as the shape of crystals, resulting in denser structures being created at higher temperatures. We applied sophisticated methods for fabricating MOFs with medicines for biological purposes. MOF nanocarriers have been shown to achieve drug delivery and controlled drug release in recent studies, making them a promising class for drug delivery, including anticancer drugs, metabolic labeling molecules. MOFs have been exploited for imaging distinction and molecular therapies in preliminary biological applications.
Chapters in this book
- Frontmatter I
- Acknowledgments V
- Contents VII
- List of contributors IX
- 1 Metal-organic framework introduction 1
- 2 Metal-organic framework properties 13
- 3 Metal-organic framework for heterogeneous catalysis 21
- 4 Homogeneous catalysis using MOFs 29
- 5 MOF: an emerging material for biomedical applications 35
- 6 Pharmaceutical wastes: an overview 51
- 7 Recent advancement and development in MOF-based materials for the removal of pharmaceutical waste 73
- 8 Future prospective of metal-organic frameworks for pharmaceutical wastes 95
- 9 MOF – a promising material for energy applications 109
- 10 Polymer-coated MOF for pharmaceutical waste removal 137
- 11 MOF-derived nanocomposites for the removal of ciprofloxacin 157
- Index 177
Chapters in this book
- Frontmatter I
- Acknowledgments V
- Contents VII
- List of contributors IX
- 1 Metal-organic framework introduction 1
- 2 Metal-organic framework properties 13
- 3 Metal-organic framework for heterogeneous catalysis 21
- 4 Homogeneous catalysis using MOFs 29
- 5 MOF: an emerging material for biomedical applications 35
- 6 Pharmaceutical wastes: an overview 51
- 7 Recent advancement and development in MOF-based materials for the removal of pharmaceutical waste 73
- 8 Future prospective of metal-organic frameworks for pharmaceutical wastes 95
- 9 MOF – a promising material for energy applications 109
- 10 Polymer-coated MOF for pharmaceutical waste removal 137
- 11 MOF-derived nanocomposites for the removal of ciprofloxacin 157
- Index 177
