7 Updates on the versatile quinoline heterocycles as anticancer agents
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Basavarajaiah Suliphuldevara Matada
, Nagesh Gunavanthrao Yernale and Jeelan N. Basha
Abstract
Quinoline motifs have befallen significant molecules due to their assortment of interest in medicine, chemical synthesis, coordination chemistry, also in the field of applied chemistry. Therefore, various researchers have produced these molecules as objective structures and studied their natal potential. The current chapter endows with concise attention about cancer, anticancer agents, sources (natural) of quinoline, and together with an innovative scope of quinoline-related medicines. Further, the present section gives knowledge concerned with the anticancer activity of synthesized quinolines and their derivatives.
Abstract
Quinoline motifs have befallen significant molecules due to their assortment of interest in medicine, chemical synthesis, coordination chemistry, also in the field of applied chemistry. Therefore, various researchers have produced these molecules as objective structures and studied their natal potential. The current chapter endows with concise attention about cancer, anticancer agents, sources (natural) of quinoline, and together with an innovative scope of quinoline-related medicines. Further, the present section gives knowledge concerned with the anticancer activity of synthesized quinolines and their derivatives.
Chapters in this book
- Frontmatter I
- Preface VII
- Contents IX
- List of contributing authors XVII
- 1 Naturally occurring, natural product inspired and synthetic heterocyclic anti-cancer drugs 1
- 2 Naturally occurring heterocyclic anticancer compounds 55
- 3 Lawsone (2-hydroxy-1,4-naphthaquinone) derived anticancer agents 83
- 4 Advances in heterocycles as DNA intercalating cancer drugs 111
- 5 Recent advances of heterocycle based anticancer hybrids 161
- 6 Fused pyrrolo-pyridines and pyrrolo-(iso) quinoline as anticancer agents 185
- 7 Updates on the versatile quinoline heterocycles as anticancer agents 249
- 8 Recent development of imidazole derivatives as potential anticancer agents 267
- 9 Recent developments in the synthesis and anti-cancer activity of acridine and xanthine-based molecules 307
- 10 Synthesis of new horizons in benzothiazole scaffold and used in anticancer drug development 343
- 11 Triazine based chemical entities for anticancer activity 387
- 12 Anticancer properties of arylchromenes and arylchromans: an overview 419
- 13 Anticancer potential of indole derivatives: an update 453
- 14 Indole based prostate cancer agents 479
- Index 503
Chapters in this book
- Frontmatter I
- Preface VII
- Contents IX
- List of contributing authors XVII
- 1 Naturally occurring, natural product inspired and synthetic heterocyclic anti-cancer drugs 1
- 2 Naturally occurring heterocyclic anticancer compounds 55
- 3 Lawsone (2-hydroxy-1,4-naphthaquinone) derived anticancer agents 83
- 4 Advances in heterocycles as DNA intercalating cancer drugs 111
- 5 Recent advances of heterocycle based anticancer hybrids 161
- 6 Fused pyrrolo-pyridines and pyrrolo-(iso) quinoline as anticancer agents 185
- 7 Updates on the versatile quinoline heterocycles as anticancer agents 249
- 8 Recent development of imidazole derivatives as potential anticancer agents 267
- 9 Recent developments in the synthesis and anti-cancer activity of acridine and xanthine-based molecules 307
- 10 Synthesis of new horizons in benzothiazole scaffold and used in anticancer drug development 343
- 11 Triazine based chemical entities for anticancer activity 387
- 12 Anticancer properties of arylchromenes and arylchromans: an overview 419
- 13 Anticancer potential of indole derivatives: an update 453
- 14 Indole based prostate cancer agents 479
- Index 503