15 Imaging Bacteria with Contrast-Enhanced Magnetic Resonance
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Abstract
Bacteria play a two part role in contrast-enhanced magnetic resonance imaging (MRI). Pathogenic bacteria are an increasingly important biomedical imaging target as cases of antibiotic-resistant bacteria and hospital infection increase. However, certain bacteria have characteristics that make them ideal for use as diagnostic and theranostic MRI contrast agents. This chapter will review the roles bacteria play in contrast-enhanced MRI. First, targeted imaging strategies of bacteria are discussed (molecular and nanomaterial) followed by the ways in which bacteria and bacterial components have been used as contrast and theranostic agents. We would like to point out that this area of MRI probes is rather embryonic and the number of reports in the literature limited.
Abstract
Bacteria play a two part role in contrast-enhanced magnetic resonance imaging (MRI). Pathogenic bacteria are an increasingly important biomedical imaging target as cases of antibiotic-resistant bacteria and hospital infection increase. However, certain bacteria have characteristics that make them ideal for use as diagnostic and theranostic MRI contrast agents. This chapter will review the roles bacteria play in contrast-enhanced MRI. First, targeted imaging strategies of bacteria are discussed (molecular and nanomaterial) followed by the ways in which bacteria and bacterial components have been used as contrast and theranostic agents. We would like to point out that this area of MRI probes is rather embryonic and the number of reports in the literature limited.
Chapters in this book
- Frontmatter i
- About the Editors v
- Historical Development and Perspectives of the Series Metal Ions in Life Sciences vii
- Preface to Volume 22 Metal Ions in Bio-Imaging Techniques ix
- Contents xiii
- Contributors to Volume 22 xix
- Titles of Volumes 1–44 in the Metal Ions in Biological Systems Series xxiii
- Contents of Volumes in the Metal Ions in Life Sciences Series xxv
- 1 Metal Ions in Bio-Imaging Techniques: A Short Overview 1
- 2 Gadolinium(III)-Based Contrast Agents for Magnetic Resonance Imaging. A Re-Appraisal 39
- 3 Manganese Complexes as Contrast Agents for Magnetic Resonance Imaging 71
- 4 Metal Ion Complexes in Paramagnetic Chemical Exchange Saturation Transfer (ParaCEST) 101
- 5 Lanthanide Complexes Used for Optical Imaging 137
- 6 Radiometals for Positron Emission Tomography (PET) Imaging 157
- 7 99mTechnetium-Based Imaging Agents and Developments in 99Tc Chemistry 195
- 8 Paramagnetic Metal Ion Probes for 19F Magnetic Resonance Imaging 239
- 9 Iron Oxide Nanoparticles for Bio-Imaging 271
- 10 Magnetic Resonance Contrast Enhancement and Therapeutic Properties of Corrole Nanoparticles 299
- 11 Positron Emission Tomography (PET) Driven Theranostics 315
- 12 Magnetic Resonance Theranostics: An Overview of Gadolinium(III)-Based Strategies and Magnetic Particle Imaging 347
- 13 Luminescence Imaging of Cancer Cells 371
- 14 Iridium(III) Complexes in Bio-Imaging Including Mitochondria 403
- 15 Imaging Bacteria with Contrast-Enhanced Magnetic Resonance 425
- 16 Transition Metals and Imaging Probes in Neurobiology and Neurodegenerative Diseases 437
- 17 Heavy Elements for X-Ray Contrast 457
- Subject Index 485
Chapters in this book
- Frontmatter i
- About the Editors v
- Historical Development and Perspectives of the Series Metal Ions in Life Sciences vii
- Preface to Volume 22 Metal Ions in Bio-Imaging Techniques ix
- Contents xiii
- Contributors to Volume 22 xix
- Titles of Volumes 1–44 in the Metal Ions in Biological Systems Series xxiii
- Contents of Volumes in the Metal Ions in Life Sciences Series xxv
- 1 Metal Ions in Bio-Imaging Techniques: A Short Overview 1
- 2 Gadolinium(III)-Based Contrast Agents for Magnetic Resonance Imaging. A Re-Appraisal 39
- 3 Manganese Complexes as Contrast Agents for Magnetic Resonance Imaging 71
- 4 Metal Ion Complexes in Paramagnetic Chemical Exchange Saturation Transfer (ParaCEST) 101
- 5 Lanthanide Complexes Used for Optical Imaging 137
- 6 Radiometals for Positron Emission Tomography (PET) Imaging 157
- 7 99mTechnetium-Based Imaging Agents and Developments in 99Tc Chemistry 195
- 8 Paramagnetic Metal Ion Probes for 19F Magnetic Resonance Imaging 239
- 9 Iron Oxide Nanoparticles for Bio-Imaging 271
- 10 Magnetic Resonance Contrast Enhancement and Therapeutic Properties of Corrole Nanoparticles 299
- 11 Positron Emission Tomography (PET) Driven Theranostics 315
- 12 Magnetic Resonance Theranostics: An Overview of Gadolinium(III)-Based Strategies and Magnetic Particle Imaging 347
- 13 Luminescence Imaging of Cancer Cells 371
- 14 Iridium(III) Complexes in Bio-Imaging Including Mitochondria 403
- 15 Imaging Bacteria with Contrast-Enhanced Magnetic Resonance 425
- 16 Transition Metals and Imaging Probes in Neurobiology and Neurodegenerative Diseases 437
- 17 Heavy Elements for X-Ray Contrast 457
- Subject Index 485
