8. Nanomaterials in the Assembly of Electrochemical DNA Sensors
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G. Evtugyn
, A. Porfireva , H. Budnikov und T. Hianik
Abstract
The development of electrochemical DNA sensors and aptasensors based on nanoparticles different in nature, size, shape, and preparation protocols has been considered with particular emphasis to the mechanism of their influence on signal readout and way of implementation in the biosensor assembly. Most attention is paid to application of Au nanoparticles and carbonaceous nanomaterials though the examples of other applications and hybrid nanomaterials are given. The analytical performance of DNA sensors and aptasensors utilizing nanomaterials is classified in accordance with their targets and role of nanoparticles in sensitivity and selectivity of the response. The trends of future progress in the biochemical applications of nanomaterials are discussed.
Abstract
The development of electrochemical DNA sensors and aptasensors based on nanoparticles different in nature, size, shape, and preparation protocols has been considered with particular emphasis to the mechanism of their influence on signal readout and way of implementation in the biosensor assembly. Most attention is paid to application of Au nanoparticles and carbonaceous nanomaterials though the examples of other applications and hybrid nanomaterials are given. The analytical performance of DNA sensors and aptasensors utilizing nanomaterials is classified in accordance with their targets and role of nanoparticles in sensitivity and selectivity of the response. The trends of future progress in the biochemical applications of nanomaterials are discussed.
Kapitel in diesem Buch
- Frontmatter I
- Preface V
- Contents IX
- List of contributing authors XV
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Part I: Nanoanalytics: Concepts, Elements, and Peculiarities
- 1. Nanoanalytics: Definitions, Classification, History, and Primary Advances 3
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Part II: Application in Spectrometric Methods
- 2. Gold Nanoparticles in Bioanalytical Techniques 55
- 3. Extinction and Emission of Nanoparticles for Application in Rapid Immunotests 87
- 4. Nanofilms as Sensitive Layers of Chemical and Biochemical Sensors 107
- 5. Energy Transfer in Liquid and Solid Nanoobjects: Application in Luminescent Analysis 131
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Part III: Application in Electroanalysis
- 6. Nanomaterials: Electrochemical Properties and Application in Sensors 165
- 7. Carbon Nanomaterials and Surfactants as Electrode Surface Modifiers in Organic Electroanalysis 223
- 8. Nanomaterials in the Assembly of Electrochemical DNA Sensors 253
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Part IV: Application in Sorption and Separation Methods
- 9. Molecularly Imprinted Polymers: Synthesis, Properties, and Application in Analysis of Real Samples 303
- 10. Sorbents Based on Carbon Nanotubes 343
- 11. Application of Microemulsions for Extraction and Preconcentration of Hydrophobic Target Compounds 389
- 12. Surfactant Micelles in Liquid Chromatography 411
- Index 442
Kapitel in diesem Buch
- Frontmatter I
- Preface V
- Contents IX
- List of contributing authors XV
-
Part I: Nanoanalytics: Concepts, Elements, and Peculiarities
- 1. Nanoanalytics: Definitions, Classification, History, and Primary Advances 3
-
Part II: Application in Spectrometric Methods
- 2. Gold Nanoparticles in Bioanalytical Techniques 55
- 3. Extinction and Emission of Nanoparticles for Application in Rapid Immunotests 87
- 4. Nanofilms as Sensitive Layers of Chemical and Biochemical Sensors 107
- 5. Energy Transfer in Liquid and Solid Nanoobjects: Application in Luminescent Analysis 131
-
Part III: Application in Electroanalysis
- 6. Nanomaterials: Electrochemical Properties and Application in Sensors 165
- 7. Carbon Nanomaterials and Surfactants as Electrode Surface Modifiers in Organic Electroanalysis 223
- 8. Nanomaterials in the Assembly of Electrochemical DNA Sensors 253
-
Part IV: Application in Sorption and Separation Methods
- 9. Molecularly Imprinted Polymers: Synthesis, Properties, and Application in Analysis of Real Samples 303
- 10. Sorbents Based on Carbon Nanotubes 343
- 11. Application of Microemulsions for Extraction and Preconcentration of Hydrophobic Target Compounds 389
- 12. Surfactant Micelles in Liquid Chromatography 411
- Index 442