Infections causing cancers: world burden and potential for prevention

Catherine de Martel; Martyn Plummer; Silvia Franceschi

doi:10.1016/j.phf.2014.07.003

Article

Infections causing cancers: world burden and potential for prevention

Catherine de Martel , Martyn Plummer and Silvia Franceschi

Published/Copyright: January 9, 2015

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From the journal Public Health Forum Volume 22 Issue 3

Abstract

Infections with viruses, bacteria, and parasites have long been identified as strong risk factors for specific cancers (Table 1) (IARC, 2012). Worldwide, about 2.1 million of the total of 12.7 million cancer cases that occurred in 2008 (16.5% of all cases) are attributable to infections (de Martel et al., 2012). This fraction varies 10-fold by region; it is lowest in North America, Australia, and New Zealand (≤ 5%) and highest in sub-Saharan Africa (>30%) (Figure 1). Helicobacter pylori, hepatitis B and C viruses, and human papillomaviruses are responsible for 1.9 million cancer cases globally, mainly encompassing gastric, liver, and cervical cancer, respectively.

Einleitung

Der Beitrag gibt einen Überblick über Infektionen, die die Entstehung bestimmter Krebsarten verursachen können und zeigt Möglichkeiten für die Prävention auf. Dabei werden Helicobacter pylori (H. pylori), Hepatitis B und C (HBV and HCV), Epstein–Barr Virus (EBV), Humane Papillomaviren (HPV) und HIV angesprochen.

Keywords: Infections; Cancer; Helicobacter pylori; Hepatitis B and C; Human papillomavirus

Schlüsselwörter: Infektionen; Krebs; Helicobacter pylori; Hepatitis B und C; Humane Papillomaviren

References

de Martel et al., 2012 de Martel C., Ferlay J., Franceschi S., Vignat J., Bray F., Forman D., Plummer M. "Global burden of cancers attributable to infections in 2008: a review and synthetic analysis" Lancet Oncol, vol. 13, 2012, p. 607–61510.1016/S1470-2045(12)70137-7. Search in Google Scholar

IARC, 2012 IARC"Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 100B: A Review of Human Carcinogens: Biological Agents" IARC Monogr Eval Carcinog Risks Hum, 2012 International Agency for Research on Cancer: Lyon. Search in Google Scholar

Plummer et al., 2014 Plummer M., Franceschi S., Vignat J., Forman D., de Martel C. "Global burden of gastric cancer attributable to Helicobacter pylori" Int J Cancer, 2014[Epub ahead of print]. Search in Google Scholar

Published Online: 2015-1-9

Published in Print: 2014-10-1

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Articles in the same Issue

https://doi.org/10.1016/j.phf.2014.07.003

Keywords for this article

Infections; Cancer; Helicobacter pylori; Hepatitis B and C; Human papillomavirus