Green synthesis of copper nanoparticles from agro-waste garlic husk

Anupama Senthilkumar; Razia Muthuswamy; Uma Maheshwari Nallal; Sankar Ramaiyan; Prabha Kannan; Sankar Muthupandi; Srimathi Priya Lakshminarayanan; Sangaraju Sambasivam; Manikandan Ayyar

doi:10.1515/zpch-2023-0291

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Green synthesis of copper nanoparticles from agro-waste garlic husk

Anupama Senthilkumar , Razia Muthuswamy , Uma Maheshwari Nallal , Sankar Ramaiyan , Prabha Kannan , Sankar Muthupandi , Srimathi Priya Lakshminarayanan , Sangaraju Sambasivam and Manikandan Ayyar

Published/Copyright: December 11, 2023

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From the journal Zeitschrift für Physikalische Chemie Volume 238 Issue 1

Abstract

The objective of this study was to test the antibacterial activity of copper nanoparticles (Cu NPs) against bacterial pathogens by green synthesizing them from aqueous extracts of garlic husk. The synthesized Cu NPs were examined by UV-visible (UV-VIS) spectroscopy at (200–400 nm), Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD) analysis, transmission electron microscopy (TEM), and zeta potential analysis. The findings supported the capping, reduction, and production of Cu NPs with an average crystalline size of 14 nm in the husk extract. The minimum inhibitory concentration technique (MIC test) was used to measure the antibacterial activity against Gram-positive (Escherichia coli, Vibrio cholera) and Gram-negative (Bacillus cereus, Staphylococcus aureus) microorganisms. The lowest concentration required for inhibiting the growth of the bacterial strains ranged from 34.7 to 43.04 μg/ml. The above findings suggest that greenly synthesized Cu NPs made from garlic agro-waste may have potential uses in the realm of nanomedicine as an antibacterial drug in the treatment and prevention of bacterial infections due to their superior antibacterial activity.

Keywords: agro-waste; garlic husk (GH); green synthesis; copper nanoparticles (Cu NPs); antibacterial activity

Corresponding authors: Razia Muthuswamy, Department of Biotechnology, Mother Teresa Women’s University, Kodaikanal, Tamil Nadu, 624101, India, E-mail: razia581@gmail.com; and Manikandan Ayyar, Department of Chemistry, Karpagam Academy of Higher Education, Coimbatore, 641021, Tamil Nadu, India; and Centre for Material Chemistry, Karpagam Academy of Higher Education, Coimbatore, 641021, Tamil Nadu, India, E-mail: manikandan.frsc@gmail.com

Research ethics: Not applicable.
Author contributions: The authors have accepted responsibility for the entire content of this manuscript and approved its submission.
Competing interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Research funding: None declared.
Data availability: Not applicable.

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Received: 2023-07-08

Accepted: 2023-11-05

Published Online: 2023-12-11

Published in Print: 2024-01-29

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Articles in the same Issue

https://doi.org/10.1515/zpch-2023-0291

Keywords for this article

agro-waste; garlic husk (GH); green synthesis; copper nanoparticles (Cu NPs); antibacterial activity