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Machine learning innovations in biomedical materials from drug discovery to personalized medicine

  • P. Nagarajan and D. David Neels Ponkumar
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Abstract

Machine learning (ML)machine learning has also introduced new paradigms to biomedical materials science for new material discovery, material optimization, and customized treatment. Pertinent to this, this chapter presents a comprehensive review of the progress and applications of ML in fabricating biomedical materials, including drug discovery and patient-specific treatment. Some of the unambiguously critical areas of ML, which are transfer learning, predictive modeling, and high-throughput screening, are discussed from the point of view of how they can be useful in improving material performance and efficiency. Despite this, the focus is on presenting use cases, especially the application of ML toward improving the systems used for drug delivery, the scaffolds employed for tissue engineering, and the “tailoring” of medical treatmentsmedical treatments. Besides offering solutions to such crucial questions as data integration, model interpretability, and computational requirements, the chapter provides readers with an idea of the future directions for research and advancement. This chapter shows how ML is a revolutionary method in biological material science and in improving patients’ lives by bridging the gap between computational and clinicalclinical utilization.

Abstract

Machine learning (ML)machine learning has also introduced new paradigms to biomedical materials science for new material discovery, material optimization, and customized treatment. Pertinent to this, this chapter presents a comprehensive review of the progress and applications of ML in fabricating biomedical materials, including drug discovery and patient-specific treatment. Some of the unambiguously critical areas of ML, which are transfer learning, predictive modeling, and high-throughput screening, are discussed from the point of view of how they can be useful in improving material performance and efficiency. Despite this, the focus is on presenting use cases, especially the application of ML toward improving the systems used for drug delivery, the scaffolds employed for tissue engineering, and the “tailoring” of medical treatmentsmedical treatments. Besides offering solutions to such crucial questions as data integration, model interpretability, and computational requirements, the chapter provides readers with an idea of the future directions for research and advancement. This chapter shows how ML is a revolutionary method in biological material science and in improving patients’ lives by bridging the gap between computational and clinicalclinical utilization.

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