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Personalized medicine using customized drug delivery systems and patient-specific material solutions, enabled by machine learning algorithms

  • P. Nagarajan and D. David Neels Ponkumar
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Abstract

Personalized medicine,personalized medicine as a distinct approach to modern healthcare system, is characterized by the targeted adaptation of medical therapy to a patient’s genome, proteome, and metabolome. This chapter outlines the development and the current status of personalized medicine, integrated with focused drug delivery systems and individualized material recipe. The author presents genomic, proteomic, and metabolomic technologies as underlying pillars of diagnostic and therapeutic advancement. Advanced sequencing technologies, high-throughput proteomics, and artificial intelligence technology analyses for enhanced clinical efficacy and resource realization are discussed. In this context, assessments of financial benefits and quality-of-life gains that have been associated with other aspects of targeted methods show their usefulness in reducing the risk of untoward medication interactions, enhancing treatmenttreatment outcomes and shortening the time needed to deliver care. Recommendations are made for future developments, with special focus on how these enhance the further growth of personalized medicine. These involve precision oncology and molecular analysis, advancement in gene editing, and incorporation of digital health assets. Thus, this chapter provides an extensive overview of their future outlook and outlines the ways that shape the advanced form of individualized medicine, impacting the current picture of healthcarehealthcare.

Abstract

Personalized medicine,personalized medicine as a distinct approach to modern healthcare system, is characterized by the targeted adaptation of medical therapy to a patient’s genome, proteome, and metabolome. This chapter outlines the development and the current status of personalized medicine, integrated with focused drug delivery systems and individualized material recipe. The author presents genomic, proteomic, and metabolomic technologies as underlying pillars of diagnostic and therapeutic advancement. Advanced sequencing technologies, high-throughput proteomics, and artificial intelligence technology analyses for enhanced clinical efficacy and resource realization are discussed. In this context, assessments of financial benefits and quality-of-life gains that have been associated with other aspects of targeted methods show their usefulness in reducing the risk of untoward medication interactions, enhancing treatmenttreatment outcomes and shortening the time needed to deliver care. Recommendations are made for future developments, with special focus on how these enhance the further growth of personalized medicine. These involve precision oncology and molecular analysis, advancement in gene editing, and incorporation of digital health assets. Thus, this chapter provides an extensive overview of their future outlook and outlines the ways that shape the advanced form of individualized medicine, impacting the current picture of healthcarehealthcare.

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