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Preparation of 188Re-lanreotide peptide and its quality control
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A. Mushtaq
Veröffentlicht/Copyright:
25. September 2009
A simple method is described for the preparation of 188Re-Lanreotide, a radiolabeled synthetic peptide derived from an analogue of somatostatin, using Lanreotide (50 μg) and stannous tartrate to which is added carrier-free 188Re. The radiolabeling has been carried out with ~555 MBq (15 mCi) with a >95% labeling efficiency and no need for subsequent purification. ITLC and HPLC techniques were employed for monitoring the stability and labeling yield. Radiolabeling results in one major peak when analyzed by reverse-phase (RP) HPLC.
Published Online: 2009-9-25
Published in Print: 2000-8-1
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Artikel in diesem Heft
- Cross-sections and linear momentum transfer in α-induced reactions on 85Rb
- Non-destructive and radiochemical determination of the neutron-induced production cross section of I-129 from Te and other neutron-induced cross sections on Te at 14.7 MeV
- Contribution of the concept of simple solutions to calculation of the density of ternary and quaternary solutions of thorium(IV) or plutonium(IV) nitrate: An(NO3)4/UO2(NO3)2/HNO3/H2O
- Sorption and desorption kinetics of Np(V) on magnetite and hematite
- Improvement in radiochemical and γ-counting procedures for the determination of 234Th in seawater
- Secondary ion mass spectrometry measurements of volcanic tuffs containing radionuclides from underground nuclear tests
- Electrochemical deposition of carrier-free radionuclides
- Sorption study of strontium onto hydrated cement phases using a sequential desorption method
- Trace detection of 41Ca in nuclear reactor concrete by diode-laser-based resonance ionization mass spectrometry
- Preparation of 188Re-lanreotide peptide and its quality control
- Comment on "Behaviour of europium(III) and its hydroxo and carbonate complexes in a solvent extraction system with HDBM in 2 M NaCl at 303 K" by M. Jiménez-Reyes, M. Solache-Rios and A. Rojas-Hernández
