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Balo’s concentric sclerosis: an update and comprehensive literature review

  • Ali Amini Harandi EMAIL logo , Akram Esfandani , Hossein Pakdaman , Mehdi Abbasi und Mohammad Ali Sahraian
Veröffentlicht/Copyright: 16. Mai 2018
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Abstract

Balo’s concentric sclerosis (BCS) is considered a variant of multiple sclerosis characterized by concentric lamella of alternating demyelinated and partially myelinated tissues. It is a rare and a relatively acute condition. Attacks may proceed rapidly over weeks or months, typically without remission, like Marburg’s variant, resulting in death or severe disability. However, the majority of cases have a more benign, self-limiting course with spontaneous remission. Magnetic resonance imaging is a primary imaging modality in the diagnosis of BCS. Treatment with intense immunosuppression may be indicated in patients with more aggressive form. New reports reveal more evidence regarding the pathophysiology and treatment strategies.

  1. Conflict of interest statement: The authors declare that they have no conflict of interest to disclose.

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Received: 2017-11-09
Accepted: 2018-03-10
Published Online: 2018-05-16
Published in Print: 2018-11-27

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