Startseite Present trends in the encapsulation of anticancer drugs
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Present trends in the encapsulation of anticancer drugs

  • Xavier Montané ORCID logo EMAIL logo , Karolina Matulewicz , Karolina Balik , Paulina Modrakowska , Marcin Łuczak , Yaride Pérez Pacheco , Belen Reig-Vano , Josep M. Montornés , Anna Bajek und Bartosz Tylkowski
Veröffentlicht/Copyright: 8. Februar 2021
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Physical Sciences Reviews
Aus der Zeitschrift Physical Sciences Reviews Band 8 Heft 2

Abstract

Different nanomedicine devices that were developed during the recent years can be suitable candidates for their application in the treatment of various deadly diseases such as cancer. From all the explored devices, the nanoencapsulation of several anticancer medicines is a very promising approach to overcome some drawbacks of traditional medicines: administered dose of the drugs, drug toxicity, low solubility of drugs, uncontrolled drug delivery, resistance offered by the physiological barriers in the body to drugs, among others. In this chapter, the most important and recent progress in the encapsulation of anticancer medicines is examined: methods of preparation of distinct nanoparticles (inorganic nanoparticles, dendrimers, biopolymeric nanoparticles, polymeric micelles, liposomes, polymersomes, carbon nanotubes, quantum dots, and hybrid nanoparticles), drug loading and drug release mechanisms. Furthermore, the possible applications in cancer prevention, diagnosis, and cancer therapy of some of these nanoparticles have been highlighted.

Keywords: anticancer drugs; cancer therapy; drug delivery systems; encapsulation; nanomedicine; nanoparticles (NPs)
Corresponding author: Xavier Montané, Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili Facultat de Quimica, Carrer Marcel·lí Domingo s/n, 43007, Tarragona, Spain, E-mail:

Acknowledgment

This work was cofinanced by the European Union from the European Social Fund under the Knowledge Education Development 2014–2020 Operational Program. Project implemented as part of the competition of the National Center for Research and Development: for Interdisciplinary Programs of Doctoral Studies on increasing the quality and effectiveness of education at doctoral studies (enrollment number: POWR.03.02.00-IP.08-00-DOK/16).

  1. Author contribution: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Conflict of interest statement: The authors declare no conflicts of interest regarding this article.

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Published Online: 2021-02-08

© 2020 Walter de Gruyter GmbH, Berlin/Boston

Artikel in diesem Heft

  1. Frontmatter
  2. Review
  3. Changes in porphyrin’s conjugation based on synthetic and post-synthetic modifications
  4. Magnetic Hybrid-Materials (Odenbach)
  5. Magnetic particle imaging of particle dynamics in complex matrix systems
  6. Reviews
  7. Computational studies on statins photoactivity
  8. Floppy molecules—their internal dynamics, spectroscopy and applications
  9. Processes and problems of pulp and paper industry: an overview
  10. Present trends in the encapsulation of anticancer drugs
https://doi.org/10.1515/psr-2020-0080
Schlagwörter für diesen Artikel
anticancer drugs; cancer therapy; drug delivery systems; encapsulation; nanomedicine; nanoparticles (NPs)

Artikel in diesem Heft

  1. Frontmatter
  2. Review
  3. Changes in porphyrin’s conjugation based on synthetic and post-synthetic modifications
  4. Magnetic Hybrid-Materials (Odenbach)
  5. Magnetic particle imaging of particle dynamics in complex matrix systems
  6. Reviews
  7. Computational studies on statins photoactivity
  8. Floppy molecules—their internal dynamics, spectroscopy and applications
  9. Processes and problems of pulp and paper industry: an overview
  10. Present trends in the encapsulation of anticancer drugs
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