Hyperoxic resuscitation after hypoxia-ischemia induces cerebral inflammation that is attenuated by tempol in a reporter mouse model with very young mice

References

[1] Back SA, Luo NL, Borenstein NS, Levine JM, Volpe JJ, Kinney HC. Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury. J Neurosci. 2001;21:1302–12.10.1523/JNEUROSCI.21-04-01302.2001Suche in Google Scholar

[2] Brazel CY, Rosti RT III, Boyce S, Rothstein RP, Levison SW. Perinatal hypoxia/ischemia damages and depletes progenitors from the mouse subventricular zone. Dev Neurosci. 2004;26:266–74.10.1159/000082143Suche in Google Scholar

[3] Craig A, Ling LN, Beardsley DJ, Wingate-Pearse N, Walker DW, Hohimer AR, et al. Quantitative analysis of perinatal rodent oligodendrocyte lineage progression and its correlation with human. Exp Neurol. 2003;181:231–40.10.1016/S0014-4886(03)00032-3Suche in Google Scholar

[4] deLange C, Brabrand K, Emblem KE, Bjornerud A, Loberg EM, Saugstad OD, et al. Cerebral perfusion in perinatal hypoxia and resuscitation assessed by transcranial contrast-enhanced ultrasound and 3 T MRI in newborn pigs. Invest Radiol. 2011;46:686–96.10.1097/RLI.0b013e3182266431Suche in Google Scholar

[5] Deng Y, Lu J, Sivakumar V, Ling EA, Kaur C. Amoeboid microglia in the periventricular white matter induce oligodendrocyte damage through expression of proinflammatory cytokines via MAP kinase signaling pathway in hypoxic neonatal rats. Brain Pathol. 2008;18:387–400.10.1111/j.1750-3639.2008.00138.xSuche in Google Scholar

[6] Dohlen G, Carlsen H, Blomhoff R, Thaulow E, Saugstad OD. Reoxygenation of hypoxic mice with 100% oxygen induces brain nuclear factor-kappa B. Pediatr Res. 2005;58:941–5.10.1203/01.PDR.0000182595.62545.EESuche in Google Scholar

[7] Felderhoff-Mueser U, Sifringer M, Polley O, Dzietko M, Leineweber B, Mahler L, et al. Caspase-1-processed interleukins in hyperoxia-induced cell death in the developing brain. Ann Neurol. 2005;57:50–9.10.1002/ana.20322Suche in Google Scholar

[8] Friberg H, Wieloch T. Mitochondrial permeability transition in acute neurodegeneration. Biochimie. 2002;84:241–50.10.1016/S0300-9084(02)01381-0Suche in Google Scholar

[9] Hagberg H. Mitochondrial impairment in the developing brain after hypoxia-ischemia. J Bioenerg Biomembr. 2004;36: 369–73.10.1023/B:JOBB.0000041770.00567.4fSuche in Google Scholar

[10] Hagberg H, Peebles D, Mallard C. Models of white matter injury: comparison of infectious, hypoxic-ischemic, and excitotoxic insults. Ment Retard Dev Disabil Res Rev. 2002;8:30–8.10.1002/mrdd.10007Suche in Google Scholar PubMed

[11] Han H. Nonnegative principal component analysis for mass spectral serum profiles and biomarker discovery. BMC Bioinformatics. 2010;11:S1.10.1186/1471-2105-11-S1-S1Suche in Google Scholar PubMed PubMed Central

[12] Kaindl AM, Sifringer M, Zabel C, Nebrich G, Wacker MA, Felderhoff-Mueser U, et al. Acute and long-term proteome changes induced by oxidative stress in the developing brain. Cell Death Differ. 2006;13:1097–109.10.1038/sj.cdd.4401796Suche in Google Scholar PubMed

[13] Karin M. Nuclear factor-kappaB in cancer development and progression. Nature. 2006;441:431–6.10.1038/nature04870Suche in Google Scholar PubMed

[14] Kaur C, Ling EA. Periventricular white matter damage in the hypoxic neonatal brain: role of microglial cells. Prog Neurobiol. 2009;87:264–80.10.1016/j.pneurobio.2009.01.003Suche in Google Scholar PubMed

[15] Kielland A, Camassa LM, Dohlen G, Munthe L, Blomhoff R, Miry-Moghaddam M, et al. NF-kappaB activity in perinatal brain during infectious and hypoxic-ischemic insults revealed by a reporter mouse. Brain Pathol. 2012;22:499–510.10.1111/j.1750-3639.2011.00548.xSuche in Google Scholar PubMed PubMed Central

[16] Kielland A, Carlsen H. Molecular imaging of transcriptional regulation during inflammation. J Inflamm (Lond). 2010; 7:20.10.1186/1476-9255-7-20Suche in Google Scholar PubMed PubMed Central

[17] Kostovic I, Judas M, Rados M, Hrabac P. Laminar organization of the human fetal cerebrum revealed by histochemical markers and magnetic resonance imaging. Cereb Cortex. 2002;12:536–44.10.1093/cercor/12.5.536Suche in Google Scholar PubMed

[18] Kutzsche S, Ilves P, Kirkeby OJ, Saugstad OD. Hydrogen peroxide production in leukocytes during cerebral hypoxia and reoxygenation with 100% or 21% oxygen in newborn piglets. Pediatr Res. 2001;49:834–42.10.1203/00006450-200106000-00020Suche in Google Scholar PubMed

[19] Lawn JE, Bahl R, Bergstrom S, Bhutta ZA, Darmstadt GL, Ellis M, et al. Setting research priorities to reduce almost one million deaths from birth asphyxia by 2015. PLoS Med. 2011;8:e1000389.10.1371/journal.pmed.1000389Suche in Google Scholar PubMed PubMed Central

[20] Markus T, Hansson S, Mer-Wahlin I, Hellstrom-Westas L, Saugstad OD, Ley D. Cerebral inflammatory response after fetal asphyxia and hyperoxic resuscitation in newborn sheep. Pediatr Res. 2007;62:71–7.10.1203/PDR.0b013e31811ead6eSuche in Google Scholar PubMed

[21] Mehta SH, Webb RC, Ergul A, Tawfik A, Dorrance AM. Neuroprotection by tempol in a model of iron-induced oxidative stress in acute ischemic stroke. Am J Physiol Regul Integr Comp Physiol. 2004;286:R283–8.10.1152/ajpregu.00446.2002Suche in Google Scholar

[22] Miller SP, Ferriero DM. From selective vulnerability to connectivity: insights from newborn brain imaging. Trends Neurosci. 2009;32:496–505.10.1016/j.tins.2009.05.010Suche in Google Scholar

[23] Perez-de-Sa V, Cunha-Goncalves D, Nordh A, Hansson S, Larsson A, Ley D, et al. High brain tissue oxygen tension during ventilation with 100% oxygen after fetal asphyxia in newborn sheep. Pediatr Res. 2009;65:57–61.10.1203/PDR.0b013e31818a01a4Suche in Google Scholar

[24] Perez-Polo JR, Reilly CB, Rea HC. Oxygen resuscitation after hypoxia ischemia stimulates prostaglandin pathway in rat cortex. Int J Dev Neurosci. 2011;29:639–44.10.1016/j.ijdevneu.2011.03.009Suche in Google Scholar

[25] Perlman JM, Wyllie J, Kattwinkel J, Atkins DL, Chameides L, Goldsmith JP, et al. Part 11: Neonatal resuscitation: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation. 2010;122:S516–38.10.1542/peds.2010-2972BSuche in Google Scholar

[26] Perrone S, Negro S, Tataranno ML, Buonocore G. Oxidative stress and antioxidant strategies in newborns. J Matern Fetal Neonatal Med. 2010;23:63–5.10.3109/14767058.2010.509940Suche in Google Scholar

[27] Puka-Sundvall M, Gilland E, Hagberg H. Cerebral hypoxia-ischemia in immature rats: involvement of mitochondrial permeability transition? Dev Neurosci. 2001;23:192–7.10.1159/000046142Suche in Google Scholar

[28] Rice JE III, Vannucci RC, Brierley JB. The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol. 1981;9:131–41.10.1002/ana.410090206Suche in Google Scholar

[29] Riddle A, Luo NL, Manese M, Beardsley DJ, Green L, Rorvik DA, et al. Spatial heterogeneity in oligodendrocyte lineage maturation and not cerebral blood flow predicts fetal ovine periventricular white matter injury. J Neurosci. 2006;26:3045–55.10.1523/JNEUROSCI.5200-05.2006Suche in Google Scholar

[30] Romijn HJ, Hofman MA, Gramsbergen A. At what age is the developing cerebral cortex of the rat comparable to that of the full-term newborn human baby? Early Hum Dev. 1991;26:61–7.10.1016/0378-3782(91)90044-4Suche in Google Scholar

[31] Rootwelt T, Odden JP, Hall C, Ganes T, Saugstad OD. Cerebral blood flow and evoked potentials during reoxygenation with 21 or 100% O₂ in newborn pigs. J Appl Physiol. 1993;75:2054–60.10.1152/jappl.1993.75.5.2054Suche in Google Scholar

[32] Segovia KN, McClure M, Moravec M, Luo NL, Wan Y, Gong X, et al. Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury. Ann Neurol. 2008;63:520–30.10.1002/ana.21359Suche in Google Scholar

[33] Vannucci RC, Vannucci SJ. Perinatal hypoxic-ischemic brain damage: evolution of an animal model. Dev Neurosci. 2005;27:81–6.10.1159/000085978Suche in Google Scholar

[34] Vannucci SJ, Hagberg H. Hypoxia-ischemia in the immature brain. J Exp Biol. 2004;207:3149–54.10.1242/jeb.01064Suche in Google Scholar

[35] Volpe JJ. Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. Lancet Neurol. 2009;8:110–24.10.1016/S1474-4422(08)70294-1Suche in Google Scholar

[36] Weissleder R, Ntziachristos V. Shedding light onto live molecular targets. Nat Med. 2003;9:123–8.10.1038/nm0103-123Suche in Google Scholar PubMed

[37] Wilcox CS, Pearlman A. Chemistry and antihypertensive effects of tempol and other nitroxides. Pharmacol Rev. 2008;60: 418–69.10.1124/pr.108.000240Suche in Google Scholar PubMed PubMed Central