Substitution Reactions on Pd(II) L-Histidine-diaqua Complexes: Comparative View from Chloride to Nucleobases and Dinucleotides
-
Nausica De Barrios
Abstract
The substitution reactions on cis-[Pd(L-Histidine)- (H2O)2 ]2 + by chloride, adenine, guanosine, adenosine, 5 -GMP, 5'-AMP, 3-AMP, d(ApG) and d(GpA) has been studied at pH = 1.0-3.0 at different temperatures. The study at physiological pH had to be avoided due to undesired polymerization reactions. The results indicate a certain degree of unsensitivity of the substitution reactions by purine based ligands at this low pH when compared with other published studies. In particular, no cooperative effect is observed in the 5'-monophosphates and N(7)adenine and N(7)guanine are found to react at the same rate within experimental error. Results agree with the published values for similar systems and differences for the 5'- and 3'-monophosphates are detected both in the monophosphates and in the dinucleotides.
© 2014 by Walter de Gruyter Berlin/Boston
Artikel in diesem Heft
- Synthesis, Acid Hydrolysis and Formation of the Molybdatopentaamminechromium(III) Ion in Aqueous Solution
- Kinetic and Mechanistic Studies on the Interaction of Adenosine with Diaquaethylenediamineplatinum(II) Ion
- On the Mechanism of Oxidation of Formate by Ni(III) (meso-5,7,7,12,14,14-hexamethy 1-1,4,8,11 - tetraazacyclotetradecane) in Aqueous Solutions
- Substitution Reactions on Pd(II) L-Histidine-diaqua Complexes: Comparative View from Chloride to Nucleobases and Dinucleotides
- Thermo-kinetic and Spectral Studies of Lanthanide(III) Complexes with 2-Hydroxy-l -benzylidene-2-furoyl Hydrazine
- Free Radical Induced Oxidation of L-Cystine by Alkaline Permanganate - A Kinetic Study
- Reaction between [Ru(H2O)6]2+ and DMF: A Complete Volume Profile of a Monocomplex Formation Reaction on a d6 Low Spin Aquaion
- Notes for Contributors Inorganic Reaction Mechanisms
- Journal Order Form
Artikel in diesem Heft
- Synthesis, Acid Hydrolysis and Formation of the Molybdatopentaamminechromium(III) Ion in Aqueous Solution
- Kinetic and Mechanistic Studies on the Interaction of Adenosine with Diaquaethylenediamineplatinum(II) Ion
- On the Mechanism of Oxidation of Formate by Ni(III) (meso-5,7,7,12,14,14-hexamethy 1-1,4,8,11 - tetraazacyclotetradecane) in Aqueous Solutions
- Substitution Reactions on Pd(II) L-Histidine-diaqua Complexes: Comparative View from Chloride to Nucleobases and Dinucleotides
- Thermo-kinetic and Spectral Studies of Lanthanide(III) Complexes with 2-Hydroxy-l -benzylidene-2-furoyl Hydrazine
- Free Radical Induced Oxidation of L-Cystine by Alkaline Permanganate - A Kinetic Study
- Reaction between [Ru(H2O)6]2+ and DMF: A Complete Volume Profile of a Monocomplex Formation Reaction on a d6 Low Spin Aquaion
- Notes for Contributors Inorganic Reaction Mechanisms
- Journal Order Form
