Bronchopulmonary Sequestration
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Nupur Verma
A 37-year-old man presented with shortness of breath and productive cough that started 1 week previously. The patient reported having recurrent pulmonary infection since adolescence. A computed tomographic angiograph showed left lower lobe dysplasia with large cystic areas and air-fluid level (image A, arrow). A supplying vessel from the aorta was found (image B, arrow), with venous drainage to the pulmonary vein. The patient was admitted to the hospital and given intravenous ceftriaxone (2 g) and intravenous azithromycin (500 mg every 24 hours), and he subsequently underwent segmentectomy. The patient had an unremarkable recovery without recurrence of pulmonary infection.


Broncopulmonary sequestration is a rare congenital abnormality and may be intralobar or extralobar.1-3 In sequestration, a segment of lung parenchyma is functionally isolated and has systemic blood supply, usually from the descending aorta.2,3 Intralobar sequestration is more common than extralobar, most often occurring in the left lower lobe, and, in most cases, presents in childhood.1 Because nearly half of the patients with intralobar sequestration present after age 20 years, this diagnosis should be considered in patients with recurrent or refractory pneumonia.1,3 Lower lobe consolidation on chest radiograph with aberrant arterial supply seen on computed tomographic images assists in making the diagnosis.3 Surgical resection of the abnormal lung tissue with segmentectomy can be curative, but in cases of more extensive infection, lobectomy is necessary.3
References
1. Tashtoush B , MemarpourR, GonzalezJ, et al. Pulmonary sequestration: a 29 patient case series and review. J Clin Diagn Res . 2015;9(12):AC05.10.7860/JCDR/2015/16004.7006Search in Google Scholar PubMed PubMed Central
2. John PR , BeasleySW, MayneV. Pulmonary sequestration and related congenital disorders. Pediatr Radiol . 1989;20(1):4-9.10.1007/BF02010625Search in Google Scholar PubMed
3. Montjoy C , HadiqueS, GraeberG, GhamandeS. Intralobar bronchopulmonary sequestration in adults over age 50: case series and review.WV Med J.2012;108(5):8-14.Search in Google Scholar
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Articles in the same Issue
- EDITORIAL
- Osteopathic Medical Education: Answering the Call
- JAOA/AACOM MEDICAL EDUCATION
- Educational Intervention in a Medically Underserved Area
- Factors Associated With Osteopathic Primary Care Residency Choice Decisions
- Interprofessional Collaborative Practice: Use of Simulated Clinical Experiences in Medical Education
- Assessment Considerations for Core Entrustable Professional Activities for Entering Residency
- Resident and Faculty Attitudes Toward Osteopathic-Focused Education
- Single Accreditation System Update: A Year of Progress
- APPENDIX
- Appendix 1: Osteopathic Graduate Medical Education, 2018
- Appendix 2: American Osteopathic Association Specialty Board Certification
- CLINICAL IMAGES
- Aortic Arch Mycotic Aneurysm
- Bronchopulmonary Sequestration
- IN YOUR WORDS
- Shared Journey in Medicine: Following in My Father's Footsteps
Articles in the same Issue
- EDITORIAL
- Osteopathic Medical Education: Answering the Call
- JAOA/AACOM MEDICAL EDUCATION
- Educational Intervention in a Medically Underserved Area
- Factors Associated With Osteopathic Primary Care Residency Choice Decisions
- Interprofessional Collaborative Practice: Use of Simulated Clinical Experiences in Medical Education
- Assessment Considerations for Core Entrustable Professional Activities for Entering Residency
- Resident and Faculty Attitudes Toward Osteopathic-Focused Education
- Single Accreditation System Update: A Year of Progress
- APPENDIX
- Appendix 1: Osteopathic Graduate Medical Education, 2018
- Appendix 2: American Osteopathic Association Specialty Board Certification
- CLINICAL IMAGES
- Aortic Arch Mycotic Aneurysm
- Bronchopulmonary Sequestration
- IN YOUR WORDS
- Shared Journey in Medicine: Following in My Father's Footsteps