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Aortic Arch Mycotic Aneurysm

  • Thomas P. Marnejon and Gulshan Man Singh Dangol
Published/Copyright: April 1, 2018

A 74-year-old man was admitted to the hospital after presenting with neck pain, sudden-onset dyspnea, and dysphagia. His vital signs were as follows: heart rate, 101 beats/min; respiration rate, 22/min; blood pressure, 144/83 mm Hg; and temperature, 96.7°F. His white blood cell count was 18,100/μL and erythrocyte sedimentation rate, 82 mm/h. Physical examination revealed wheezing, tachycardia, and bilateral lower extremity edema. Chest computed tomographic scan revealed a 6-cm anterior mediastinal mass. A magnetic resonance image revealed a pseudoaneurysm of the aortic arch beyond the left subclavian artery origin (image A, arrow) with an abscess surrounding the aneurysm (image B, arrow). The patient was given vancomycin intravenously and transitioned to nafcillin, 2 g every 4 hours, after blood culture results were positive for Staphylococcus aureus on hospital day 3. Magnetic resonance image of the cervical spine showed discitis and osteomyelitis from C6 to C7, with epidural abscess and prevertebral space fluid, extending inferiorly to the aorta. The patient died on hospital day 10.

The term mycotic aneurysm was first described by Osler in a case of ulcerative bacterial endocarditis, in which ulcerative endarteritis in the aortic arch produced multiple aneurysms.1 Direct inoculation, contiguous infection, bacterial seeding, or septic emboli can cause mycotic aneurysm.2-6 Management includes antibiotics, debridement, and revascularization.7


From the Department of Internal Medicine at the Northeast Ohio Medical University in Rootstown (Drs Marnejon and Dangol); the Lake Erie College of Osteopathic Medicine in Erie, Pennsylvania (Dr Marnejon); the Ohio University Heritage College of Osteopathic Medicine in Athens (Dr Marnejon); and the St Elizabeth Youngstown Hospital in Ohio (Drs Marnejon and Dangol).
Financial Disclosures: None reported.
Support: None reported.

*Address correspondence to Thomas P. Marnejon, DO, St Elizabeth Health Center, Department of Internal Medicine, 1044 Belmont Ave, Youngstown, OH 44501-1096. Email:


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Received: 2017-09-12
Accepted: 2017-09-18
Published Online: 2018-04-01
Published in Print: 2018-04-01

© 2018 American Osteopathic Association

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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