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AOT-Vesicles Produced at the Oil-Water Interface

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Published/Copyright: April 11, 2013
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Tenside Surfactants Detergents
From the journal Tenside Surfactants Detergents Volume 48 Issue 3

Abstract

Vesicles can be found in many applications like drug delivery or as models for cell membranes. It is often necessary to produce vesicles which are easy to adjust in size and which can be filled with different types of ingredients. In this publication we used phase transfer techniques in to form well defined vesicles. The synthesis of these particles occurred in three different steps. First, a water phase was covered by an oil phase containing surfactants. A water-in-oil emulsion was then added to the oil phase. In the third step the phase transfer was stimulated by sedimentation or centrifugation processes. In a series of experiments we measured the vesicle sizes and encapsulation efficiencies. Giant vesicles, formed by sedimentation processes had typical sizes between 1–10 μm. Smaller vesicles between 100–500 nm were observed after centrifugation processes. With both methods we could produce vesicles with encapsulation amounts about 10%.

Kurzfassung

Vesikel haben zahlreiche Anwendungen, z.B. als Transportbehälter für Wirkstoffe oder als Modellmembranen für Zellen. Es ist oft notwendig, Vesikel herzustellen, deren Größe und eingebaute Wirkstoffmenge variiert werden kann. Wir präsentieren hier die Herstellung von Vesikeln durch Phasentransfer. Dieser Prozess erfolgt in drei Schritten. Zuerst wird eine tensidhaltige Ölphase über eine Wasserphase geschichtet. Eine Wasser-in-Öl-Emulsion wird dann zu der Ölphase gegeben. Im dritten Schritt erfolgt der Phasentransfer durch Sedimentation oder durch Zentrifugation. In einer Reihe von Experimenten untersuchten wir die Vesikelgrößen und die Einbaueffizienzen. Durch Sedimentationsprozesse wurden riesige Vesikel im Größenbereich von 1–10 μm hergestellt. Zentrifugationsprozesse führten zur Bildung von kleineren Vesikeln im Größenbereich zwischen 100–500 nm. Mit beiden Methoden konnten Einbaueffizienzen von ca. 10% erreicht werden.

Key words:: Vesicle; phase transfer; emulsion; bending elasticity
Stichwörter:: Vesikel; Phasentransfer; Emulsion; Biegesteifigkeit
∗ Evelin Kubatta, Department of Physical Chemistry II, Technische Universität Dortmund, 44227 Dortmund, Otto-Hahn-Str. 6, Germany. E-Mail: , Tel.: 0049-(0)231-7555030, Fax: 0049-(0)231-7555367

Evelin A. Kubatta was born in May 1983. She did her diploma in 2007, from TU Dortmund, Germany. Currently she is working as Ph.D. student in the working group of Prof. Dr. Rehage, Department of Physical Chemistry, TU Dortmund, Germany.

Prof. Dr. Heinz Rehage was born in September 1952, studied for his diploma at TU Clausthal-Zellerfeld, Germany. After obtaining his Ph. D. in 1982 and his postdoctoral lecture qualification in 1989 at the university in Bayreuth, Germany, he joined the university of Essen-Duisburg as Professor in the Department of Physical Chemistry in 1991. At present he is working as Professor and Dean, Department of Phyiscal Chemistry, TU Dortmund, Germany, is an associated member of the IUPAC commission 160 “Colloid and Surface Chemistry including Catalysi” and an associated member of the GVC-commission “Grenzflächen”.

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Received: 2011-02-02
Published Online: 2013-04-11
Published in Print: 2011-05-01

© 2011, Carl Hanser Publisher, Munich

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https://doi.org/10.3139/113.110125
Keywords for this article
Vesicle; phase transfer; emulsion; bending elasticity

Articles in the same Issue

  1. Contents/Inhalt
  2. Contents
  3. Abstracts
  4. Abstracts
  5. Application
  6. Impact of Surfactants on the Efficacy of Iron Oxide Dispersants
  7. Influence of Surfactants on the Morphologies of CdS Nanorods
  8. Optimization of Parameters for the Preparation of Au/TiO2 with Photodegradation of NPE-10 in Aqueous Solution
  9. Synthesis
  10. Synthesis of Disk-Like and Flower-Like ZnO Nanostructures by Sodium Dodecyl Sulfate-Assisted non-Basic Solution Process
  11. Cleaning Technology
  12. Using Fabric Softeners, Drying and Ironing in Germany
  13. Physical Chemistry
  14. AOT-Vesicles Produced at the Oil-Water Interface
  15. Interactions between Dyes and Cetyl-trimethyl Ammonium Bromide
  16. Effects of Electrolytes on Interfacial and Micelle Properties of C.I. Reactive Orange 16 – Dodecylpyridinium Chloride Binary System
  17. Novel Surfactants
  18. Bis(Diquaternary Ammonium)Salts: Synthesis, Effect of Spacer on Surface Activities and Aggregation Properties of Reactive Red 198 in Aqueous – Surfactants Solutions
  19. Research Group Portrait
  20. Colloid and Interfacial Chemistry at Stuttgart University
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