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Methyltrioxorhenium-catalysed oxidation of secondary amines to nitrones in ionic liquids

  • Mária Mečiarová EMAIL logo , Melinda Mojzesová und Radovan Šebesta
Veröffentlicht/Copyright: 20. September 2012
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Abstract

Nitrones serve as starting materials for the synthesis of many heterocycles. Oxidation of secondary amines using hydrogen peroxide and the catalytic amount of methyltrioxorhenium in ionic liquids is a useful method for the preparation of nitrones. Ultrasonic irradiation and ionic liquids have a positive influence on the reaction. The nitrones required were isolated in good yields. Corresponding hydroxylamines, which can be easily oxidised to nitrones, often accompanied the main products. Methyltrioxorhenium in ionic liquids was re-used in several reaction cycles without any deteriorating effect on the course of the reaction.

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Published Online: 2012-9-20
Published in Print: 2013-1-1

© 2012 Institute of Chemistry, Slovak Academy of Sciences

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