Surface-modified phillipsite-rich tuff from the Campania region (southern Italy) as a promising drug carrier: An ibuprofen sodium salt trial
-
Mariano Mercurio
, Francesco Izzo
, Alessio Langella , Celestino Grifa , Chiara Germinario , Aleksandra Daković , Paolo Aprea , Rossana Pasquino , Piergiulio Cappelletti , Fabio Sossio Graziano and Bruno de Gennaro
Abstract
The encapsulation and delivery of drugs often involves the use of expensive microporous materials, and we have investigated the potential for natural zeolites from the widespread volcanic formations of southern Italy as alternatives to these carriers. Surface-modified natural zeolites (SMNZs) with diverse micellar structures (patchy and complete bilayers) were obtained by using different cationic surfactants [cetylpyridinium chloride (CP-Cl), benzalkonium chloride (BC-Cl), hexadecyltrimethylammonium chloride (HDTMA-Cl), and bromide (HDTMA-Br) with phillipsite-rich tuff from the Campania region (southern Italy)]. Loading and release kinetics tests of sodium ibuprofen (IBU) were carried out with organo-phillipsite composites using Fourier transform infrared spectroscopy (FTIR) and thermal analysis coupled with evolved gas analysis (EGA). Results from these tests were mathematically modeled to evaluate IBU adsorption and release mechanisms.
The maximum loaded amount of IBU was attained for organo-phillipsite modified with HDTMA-Br (PHB), which showed a complete bilayer micellar structure. Whenever a patchy bilayer micellar structure formed, the lowest adsorptions of IBU were observed. Equilibrium adsorption results were fit using Langmuir, Sips, and Toth models. Pseudo-first-order and pseudo-second-order fits to the loading kinetic data provided significant goodness of fit. Good fits to the release kinetic data were obtained using first-order and Weibull equations, shedding new light on the release mechanism of IBU from phillipsite. The active amount of IBU on the modified zeolite surface was almost totally available for pharmaceutical purposes.
Acknowledgments
This work was carried out with the financial support of MIUR (Ministero delľIstruzione, delľUniversitá e della Ricerca) Progetti di Ricerca di Interesse Nazionale (PRIN 2010). The authors thank K. Putirka and two anonymous referees for their suggestions, which deeply improved the manuscript. The authors are also in debt to L. Campbell and D.L. Bish for the invaluable contribution to the clarity of the manuscript.
References cited
Ambrogi, V., Fardella, G., Grandolini, G., and Perioli, L. (2001) Intercalation compounds of hydrotalcite-like anionic clays with antiinflammatory agents—I. Intercalation and in vitro release of ibuprofen. International Journal of Pharmaceutics, 220, 23–32.10.1016/S0378-5173(01)00629-9Search in Google Scholar
Barczyk, K., Mozgawa, W., and Król, M. (2014) Studies of anions sorption on natural zeolites. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 133, 876–882.10.1016/j.saa.2014.06.065Search in Google Scholar
Bhaskar, R., Murthy, R.S.R., Miglani, B.D., and Viswanathan, K. (1986) Novel method to evaluate diffusion controlled release of drug from resinate. International Journal of Pharmaceutics, 28, 59–66.10.1016/0378-5173(86)90147-XSearch in Google Scholar
Bish, D.L. (1984) Effects of exchangeable cation composition on the thermal expansion/contraction of clinoptilolite. Clays and Clay Minerals, 32, 444–452.10.1346/CCMN.1984.0320602Search in Google Scholar
Bish, D.L. (1988) Effects of composition on the dehydration behavior of clinoptilolite and heulandite. In D. Kalló and H.S. Sherry, Eds., Occurrence, Properties and Utilization of Natural Zeolites, p. 565–576. Akadémiai Kiadó, Budapest.Search in Google Scholar
Bish, D.L., and Carey, J.W. (2001) Thermal behavior of natural zeolites. Reviews in Mineralogy and Geochemistry, 45, 403–452.10.2138/rmg.2001.45.13Search in Google Scholar
Bowman, R.S. (2003) Applications of surfactant-modified zeolites to environmental remediation. Microporous and Mesoporous Materials, 61, 43–56.10.1016/S1387-1811(03)00354-8Search in Google Scholar
Buondonno, A., Colella, A., Coppola, E., de Gennaro, M., Grilli, E., Langella, A., and Rubino, M. (2008) Distribution of Al, Ca, Fe and Mg in weathering extracts from Campanian Ignimbrite (yellow facies). Studies in Surface Science and Catalysis, 174, 525–528.10.1016/S0167-2991(08)80255-8Search in Google Scholar
Byrappa, K., and Kumar, B.V.S. (2007) Characterization of zeolites by infrared spectroscopy. Asian Journal of Chemistry, 19, 4933–4935.Search in Google Scholar
Calcaterra, D., Cappelletti, P., Langella, A., Colella, A., and de Gennaro, M. (2004) The ornamental stones of Caserta province: the Campanian Ignimbrite in the medieval architecture of Casertavecchia. Journal of Cultural Heritage, 5, 137–148.10.1016/j.culher.2003.08.003Search in Google Scholar
Campbell, L.S., and Davies, B.E. (1995) Soil sorption of caesium modelled by the Langmuir and Freundlich isotherm equations. Applied Geochemistry, 10, 715–723.10.1016/0883-2927(95)00056-9Search in Google Scholar
Cappelletti, P., Cerri, G., Colella, A., de Gennaro, M., Langella, A., Perrotta, A., and Scarpati, C. (2003) Post-eruptive processes in the Campanian Ignimbrite. Mineralogy and Petrology, 79, 79–97.10.1007/s00710-003-0003-7Search in Google Scholar
Cappelletti, P., Rapisardo, G., de Gennaro, B., Colella, A., Langella, A., Graziano, S.F., Bish, D.L., and de Gennaro, M. (2011) Immobilization of Cs and Sr in aluminosilicate matrices derived from natural zeolites. Journal of Nuclear Materials, 414, 451–457.10.1016/j.jnucmat.2011.05.032Search in Google Scholar
Cappelletti, P., Colella, A., Langella, A., Mercurio, M., Catalanotti, L., Monetti, V., and de Gennaro, B. (2017) Use of surface modified natural zeolite (SMNZ) in pharmaceutical preparations Part 1. Mineralogical and technological characterization of some industrial zeolite-rich rocks. Microporous and Mesoporous Materials, 250, 232–244.10.1016/j.micromeso.2015.05.048Search in Google Scholar
Carey, J.W., and Bish, D.L. (1996) Equilibrium in the clinoptilolite-H2O system. American Mineralogist, 81, 952–962.10.2138/am-1996-7-817Search in Google Scholar
Cerri, G., de Gennaro, M., Bonferoni, M.C., and Caramella, C. (2004) Zeolites in biomedical application: Zn-exchanged clinoptilolite-rich rock as active carrier for antibiotics in anti-acne topical therapy. Applied Clay Science, 27, 141–150.10.1016/j.clay.2004.04.004Search in Google Scholar
Cerri, G., Farina, M., Brundu, A., Daković, A., Giunchedi, P., Gavini, E., and Rassu, G. (2016) Natural zeolites for pharmaceutical formulations: Preparation and evaluation of a clinoptilolite-based material. Microporous and Mesoporous Materials, 223, 58–67.10.1016/j.micromeso.2015.10.034Search in Google Scholar
Chen, C. (2013) Evaluation of equilibrium sorption isotherm equations. The Open Chemical Engineering Journal, 7, 24–44.10.2174/1874123101307010024Search in Google Scholar
Colella, C., de Gennaro, M., Langella, A., and Pansini, M. (1998) Evaluation of natural phillipsite and chabaziteas cation exchangers for copper and zinc. Separation Science and Technology, 33, 467–481.10.1080/01496399808544991Search in Google Scholar
Colella, A., Calcaterra, D., Cappelletti, P., Di Benedetto, C., Langella, A., Papa, L., Perrotta, A., Scarpati, C., and de Gennaro, M. (2013) Il Tufo Giallo Napoletano. In Le pietre storiche della Campania dalľoblio alla riscoperta, p. 129–154. Luciano Editore.Search in Google Scholar
Colella, A., Di Benedetto, C., Calcaterra, D., Cappelletti, P., D’Amore, M., Di Martire, D., Graziano, S.F., Papa, L., de Gennaro, M., and Langella, A. (2017) The Neapolitan Yellow Tuff: An outstanding example of heterogeneity. Construction and Building Materials, 136, 361–373.10.1016/j.conbuildmat.2017.01.053Search in Google Scholar
Coombs, D.S., Alberti, A., Armbruster, T., Artioli, G., Colella, C., Galli, E., Grice, J.D., Liebau, F., Mandarino, J.A., Minato, H., and others. (1997) Recommended nomenclature for zeolite minerals: Report of the subcommittee on zeolites of the International Mineralogical Association, Commission on new Minerals and Mineral names. Canadian Mineralogist, 35, 1571–1606.Search in Google Scholar
Coppola, E., Battaglia, G., Bucci, M., Ceglie, D., Colella, A., Langella, A., Boundonno, A., and Colella, C. (2003) Remediation of Cd- and Pb-polluted soil by treatment with oigano-zeolite conditioner. Clays and Clay Minerals, 51, 609–615.10.1346/CCMN.2003.0510603Search in Google Scholar
Costa, P., and Sousa Lobo, J.M. (2001) Modeling and comparison of dissolution profiles. European Journal of Pharmaceutical Sciences, 13, 123–133.10.1016/S0928-0987(01)00095-1Search in Google Scholar
Costa, F.O., Sousa, J.J.S., Pais, A.A.C.C., and Formosinho, S.J. (2003) Comparison of dissolution profiles of Ibuprofen pellets. Journal of Controlled Release, 89, 199–212.10.1016/S0168-3659(03)00033-6Search in Google Scholar
Dash, S., Murthy, P.N., Nath, L., and Chowdhury, P. (2010) Kinetic modeling on drug release from controlled drug delivery systems. Acta Poloniae Pharmaceutica, 67, 217–23.Search in Google Scholar
de Gennaro, B., Catalanotti, L., Bowman, R.S., and Mercurio, M. (2014) Anion exchange selectivity of surfactant modified clinoptilolite-rich tuff for environmental remediation. Journal of Colloid and Interface Science, 430, 178–183.10.1016/j.jcis.2014.05.037Search in Google Scholar
de Gennaro, B., Catalanotti, L., Cappelletti, P., Langella, A., Mercurio, M., Serri, C., Biondi, M., and Mayol, L. (2015) Surface modified natural zeolite as a carrier for sustained diclofenac release: A preliminary feasibility study. Colloids and Surfaces B: Biointerfaces, 130, 101–109.10.1016/j.colsurfb.2015.03.052Search in Google Scholar
de Gennaro, B., Mercurio, M., Cappelletti, P., Catalanotti, L., Daković, A., De Bonis, A., Grifa, C., Izzo, F., Kraković, M., Monetti, V., and others. (2016) Use of surface modified natural zeolite (SMNZ) in pharmaceutical preparations. Part 2. A new approach for a fast functionalization of zeolite-rich carriers. Microporous and Mesoporous Materials, 235, 42–49.10.1016/j.micromeso.2016.07.043Search in Google Scholar
de Gennaro, B., Izzo, F., Catalanotti, L., Langella, A., and Mercurio, M. (2017) Surface modified phillipsite as a potential carrier for NSAIDs release. Advanced Science Letters, 23, 5941–5943.10.1166/asl.2017.9075Search in Google Scholar
de Gennaro, M., Colella, C., Pansini, M., and Langella, A. (1992) Reconstruction of a natural zeolitization process through laboratory simulations. In Ninth International Zeolite Conference, 2, p. 207–214. Butterworth-Heinemann, Boston.10.1016/B978-1-4832-8383-8.50109-4Search in Google Scholar
de Gennaro, M., Colella, C., Langella, A., and Cappelletti, P. (1995) Decay of Campanian ignimbrite stoneworks in some monuments of the Caserta area. Science and Technology for Cultural Heritage, 4, 75–86.Search in Google Scholar
de Gennaro, M., Langella, A., Cappelletti, P., and Colella, C. (1999) Hydrothermal conversion of trachytic glass to zeolite. 3. Monocationic model glasses. Clays and Clay Minerals, 47, 348–357.10.1346/CCMN.1999.0470311Search in Google Scholar
de Gennaro, M., Calcaterra, D., Cappelletti, P., Langella, A., and Morra, V. (2000) Building stone and related weathering in the architecture of the ancient city of Naples. Journal of Cultural Heritage, 1, 399–414.10.1016/S1296-2074(00)01096-7Search in Google Scholar
de Gennaro, R., Cappelletti, P., Cerri, G., de Gennaro, M., Dondi, M., Guarini, G., Langella, A., and Naimo, D. (2003) Influence of zeolites on the sintering and technological properties of porcelain stoneware tiles. Journal of the European Ceramic Society, 23, 2237–2245.10.1016/S0955-2219(03)00086-4Search in Google Scholar
de Gennaro, R., Cappelletti, P., Cerri, G., de Gennaro, M., Dondi, M., and Langella, A. (2004) Zeolitic tuffs as raw materials for lightweight aggregates. Applied Clay Science, 25, 71–81.10.1016/j.clay.2003.08.005Search in Google Scholar
de Gennaro, R., Cappelletti, P., Cerri, G., de Gennaro, M., Dondi, M., and Langella, A. (2005) Neapolitan Yellow Tuff as raw material for lightweight aggregates in lightweight structural concrete production. Applied Clay Science, 28, 309–319.10.1016/j.clay.2004.01.014Search in Google Scholar
de Gennaro, R., Cappelletti, P., Cerri, G., de Gennaro, M., Dondi, M., Graziano, S.F., and Langella, A. (2007) Campanian Ignimbrite as raw material for lightweight aggregates. Applied Clay Science, 37, 115–126.10.1016/j.clay.2006.11.004Search in Google Scholar
de Gennaro, R., Langella, A., D’Amore, M., Dondi, M., Colella, A., Cappelletti, P., and de Gennaro, M. (2008) Use of zeolite-rich rocks and waste materials for the production of structural lightweight concretes. Applied Clay Science, 41, 61–72.10.1016/j.clay.2007.09.008Search in Google Scholar
Dondi, M., Cappelletti, P., D’Amore, M., de Gennaro, R., Graziano, S.F., Langella, A., Raimondo, M., and Zanelli, C. (2016) Lightweight aggregates from waste materials: Reappraisal of expansion behavior and prediction schemes for bloating. Construction and Building Materials, 127, 394–409.10.1016/j.conbuildmat.2016.09.111Search in Google Scholar
Esposito, S., Marocco, A., DelľAgli, G., de Gennaro, B., and Pansini, M. (2015) Relationships between the water content of zeolites and their cation population. Microporous and Mesoporous Materials, 202, 36–43.10.1016/j.micromeso.2014.09.041Search in Google Scholar
Fialips, C.I., Carey, J.W., and Bish, D.L. (2005) Hydration-dehydration behavior and thermodynamics of chabazite. Geochimica et Cosmochimica Acta, 69, 2293–2308.10.1016/j.gca.2004.11.007Search in Google Scholar
Foo, K.Y., and Hameed, B.H. (2010) Insights into the modeling of adsorption isotherm systems. Chemical Engineering Journal, 56, 2–10.10.1016/j.cej.2009.09.013Search in Google Scholar
Gabriele, G.A., and Ragsdell, K.M. (1977) The generalized reduced gradient method: A reliable tool for optimal design. Journal of Engineering for Industry, 99, 394–400.10.1115/1.3439249Search in Google Scholar
Gatta, G.D., Cappelletti, P., de Gennaro, B., Rotiroti, N., and Langella, A. (2015) New data on Cu-exchanged phillipsite: a multi-methodological study. Physics and Chemistry of Minerals, 42, 723–733.10.1007/s00269-015-0757-6Search in Google Scholar
Gondalia, R., Mashru, R., and Savaliya, P. (2010) Development and validation of spectrophotometric methods for simultaneous estimation of ibuprofen and paracetamol in soft gelatin capsule by simultaneous equation method. International Journal of Chemtech Research, 2, 1881–1885.Search in Google Scholar
Hailu, S.L., Nair, B.U., Redi-Abshiro, M., Diaz, I., and Tessema, M. (2017) Preparation and characterization of cationic surfactant modified zeolite adsorbent material for adsorption of organic and inorganic industrial pollutants. Journal of Environmental Chemical Engineering, 5, 3319–3329.10.1016/j.jece.2017.06.039Search in Google Scholar
Higuchi, T. (1963) Mechanism of sustained-action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices. Journal of Pharmaceutical Sciences, 52, 1145–1149.10.1002/jps.2600521210Search in Google Scholar
Hinz, C. (2001) Description of sorption data with isotherm equations. Geoderma, 99, 225–243.10.1016/S0016-7061(00)00071-9Search in Google Scholar
Ho, Y.S. (2004) Citation review of Lagergren kinetic rate equation on adsorption reactions. Scientometrics, 59, 171–177.10.1023/B:SCIE.0000013305.99473.cfSearch in Google Scholar
Ho, Y.S. (2006) Review of second-order models for adsorption systems. Journal of Hazardous Materials, 136, 681–689.10.1016/j.jhazmat.2005.12.043Search in Google Scholar PubMed
Ho, Y.-S., Chiu, W.-T., and Wang, C.-C. (2005) Regression analysis for the sorption isotherms of basic dyes on sugarcane dust. Bioresource Technology, 96, 1285–1291.10.1016/j.biortech.2004.10.021Search in Google Scholar PubMed
Izzo, F., Mercurio, M., Aprea, P., Cappelletti, P., de Gennaro, B., Germinario, C., Grifa, C., Pasquino, R., and Langella, A. (2017) Technological performance of Surface Modified Natural Zeolite (SMNZ) for in vitro loading/release of ibuprofen sodium salt: new insights on chabazite-rich tuff. Geosciences: A Tool in a Changing World, p. 221. Pisa.Search in Google Scholar
Janićijević, J., Krajišnik, D., Ćalija, B., Vasiljević, B.N., Dobričić, V., Daković, A., Antonijević, M.D., and Milić, J. (2015) Modified local diatomite as potential functional drug carrier—A model study for diclofenac sodium. International Journal of Pharmaceutics, 496, 466–474.10.1016/j.ijpharm.2015.10.047Search in Google Scholar PubMed
Joshi, R.S., Pawar, N.S., Katiyar, S.S., Zope, D.B., and Shinde, A.T. (2011) Development and validation of UV spectrophotometric methods for simultaneous estimation of Paracetamol and Ibuprofen in pure and tablet dosage form. Der Pharmacia Sinica, 2, 164–171.Search in Google Scholar
Karge, H.G. (2001) Characterization by IR spectroscopy. In H. Robson and K.P. Lillerud, Eds., Verified Syntheses of Zeolitic Materials, p. 69–71. Wiley.10.1016/B978-044450703-7/50113-7Search in Google Scholar
Krajišnik, D., Milojević, M., Malenović, A., Daković, A., Ibrić, S., Savić, S., Dondur, V., Matijašević, S., Radulović, A., Daniels, R., and others (2010a) Cationic surfactants-modified natural zeolites: improvement of the excipients functionality. Drug Development and Industrial Pharmacy, 36, 1215–1224.10.3109/03639041003695121Search in Google Scholar PubMed
Krajišnik, D., Daković, A., Malenović, A., Milojević, M., Dondur, V., and Milić, J. (2010b) Cationic surfactants-modified natural zeolites: potential excipients for anti-inflammatory drugs. In Proceedings of the 3rd Croatian-Slovenian Symposium on Zeolites, Trogir, Croatia pp. 23–26.Search in Google Scholar
Krajišnik, D., Daković, A., Milojević, M., Malenović, A., Kragović, M., Bogdanović, D.B., Dondur, V., and Milić, J. (2011) Properties of diclofenac sodium sorption onto natural zeolite modified with cetylpyridinium chloride. Colloids and Surfaces B: Biointerfaces, 83, 165–172.10.1016/j.colsurfb.2010.11.024Search in Google Scholar PubMed
Krajišnik, D., Daković, A., Malenović, A., Djekić, L., Kragović, M., Dobričić, V., and Milić, J. (2013a) An investigation of diclofenac sodium release from cetylpyridinium chloride-modified natural zeolite as a pharmaceutical excipient. Microporous and Mesoporous Materials, 167, 94–101.10.1016/j.micromeso.2012.03.033Search in Google Scholar
Krajišnik, D., Daković, A., Malenović, A., Milojević-Rakić, M., Dondur, V., Radulović, Ž., and Milić, J. (2013b) Investigation of adsorption and release of diclofenac sodium by modified zeolites composites. Applied Clay Science, 83–84, 322–326.10.1016/j.clay.2013.08.011Search in Google Scholar
Krajišnik, D., Daković, A., Malenović, A., Kragović, M., and Milić, J. (2015) Ibuprofen sorption and release by modified natural zeolites as prospective drug carriers. Clay Minerals, 50, 11–22.10.1180/claymin.2015.050.1.02Search in Google Scholar
Kranz, R.L., Bish, D.L., and Blacic, J.D. (1989) Hydration and dehydration of Zeolitic Tuff from Yucca Mountain, Nevada. Geophysical Research Letters, 16, 1113–1116.10.1029/GL016i010p01113Search in Google Scholar
Langella, A., De Simone, P., Calcaterra, D., Cappelletti, P., and de Gennaro, M. (2002) Evidence of the relationship occurring between zeolitization and lithification in the yellow facies of Campanian Ignimbrite (southern Italy). Studies in Surface Science and Catalysis, 142, 1775–1782.10.1016/S0167-2991(02)80352-4Search in Google Scholar
Langella, A., Pansini, M., Cerri, G., Cappelletti, P., and de Gennaro, M. (2003) Thermal behavior of natural and cation-exchanged clinoptilolite from Sardinia (Italy). Clays and Clay Minerals, 51, 625–633.10.1346/CCMN.2003.0510605Search in Google Scholar
Langella, A., Bish, D.L., Cappelletti, P., Cerri, G., Colella, A., de Gennaro, R., Graziano, S.F., Perrotta, A., Scarpati, C., and de Gennaro, M. (2013) New insights into the mineralogical facies distribution of Campanian Ignimbrite, a relevant Italian industrial material. Applied Clay Science, 72, 55–73.10.1016/j.clay.2013.01.008Search in Google Scholar
Langmuir, I. (1916) The constitution and fundamental properties of solids and liquids. Part I. Solids. Journal of the American Chemical Society, 252, 2221–2295.10.1021/ja02268a002Search in Google Scholar
Larsson, D.G.J. (2014) Pollution from drug manufacturing: review and perspectives. Philosophical Transactions of the Royal Society of London B, Biological Sciences, 369, 7 p. 10.1098/rstb.2013.0571.Search in Google Scholar PubMed PubMed Central
Li, Z., and Bowman, R.S. (1997) Counterion effects on the sorption of cationic surfactant and chromate on natural clinoptilolite. Environmental Science and Technology, 31, 2407–2412.10.1021/es9610693Search in Google Scholar
Li, Z., and Bowman, R.S. (1998) Sorption of chromate and PCE by surfactant-modified clay minerals. Environmental Engineering Science, 15, 237–245.10.1089/ees.1998.15.237Search in Google Scholar
Li, Z., and Bowman, R.S. (2001) Regeneration of surfactant-modified zeolite after saturation with chromate and perchloroethylene. Water Research, 35, 322–326.10.1016/S0043-1354(00)00258-XSearch in Google Scholar
Li, Z., Anghel, I., and Bowman, R.S. (1998) Sorption of oxyanions by surfactant-modified zeolite. Journal of Dispersion Science and Technology, 19, 843–857.10.1080/01932699808913218Search in Google Scholar
Li, Z., Jones, H.K., Bowman, R.S., and Helferich, R. (1999) Enhanced reduction of chromate and PCE by pelletized surfactant-modified zeolite/zerovalent iron. Environmental Science and Technology, 33, 4326–4330.10.1021/es990334sSearch in Google Scholar
Limousin, G., Gaudet, J.P., Charlet, L., Szenknect, S., Barthés, V., and Krimissa, M. (2007) Sorption isotherms: A review on physical bases, modeling and measurement. Applied Geochemistry, 22, 249–275.10.1016/j.apgeochem.2006.09.010Search in Google Scholar
Lin, J., and Wang, L. (2009) Comparison between linear and nonlinear forms of pseudo-first-order and pseudo-second-order adsorption kinetic models for the removal of methylene blue by activated carbon. Frontiers of Environmental Science & Engineering in China, 3, 320–324.10.1007/s11783-009-0030-7Search in Google Scholar
Markandeya, S.P., and Kisku, G.C. (2015) Linear and nonlinear kinetic modeling for adsorption of disperse dye in batch process. Research Journal of Environmental Toxicology, 9, 320–331.10.3923/rjet.2015.320.331Search in Google Scholar
Marković, M., Daković, A., Krajišnik, D., Kragović, M., Milić, J., Langella, A., de Gennaro, B., Cappelletti, P., and Mercurio, M. (2016) Evaluation of the surfactant/phillipsite composites as carriers for diclofenac sodium. Journal of Molecular Liquids, 222, 711–716.10.1016/j.molliq.2016.07.127Search in Google Scholar
Marković, M., Daković, A., Rottinghaus, G.E., Kragović, M., Petković, A., Krajišnik, D., Milić, J., Mercurio, M., and de Gennaro, B. (2017) Adsorption of the mycotoxin zearalenone by clinoptilolite and phillipsite zeolites treated with cetylpyridinium surfactant. Colloids and Surfaces B: Biointerfaces, 151, 324–332.10.1016/j.colsurfb.2016.12.033Search in Google Scholar PubMed
Mercurio, M., Mercurio, V., de Gennaro, B., de Gennaro, M., Grifa, C., Langella, A., and Morra, V. (2010) Natural zeolites and white wines from Campania region (Southern Italy): a new contribution for solving some oenological problems. Periodico di Mineralogia, 79, 95–112.Search in Google Scholar
Mercurio, M., Langella, A., Cappelletti, P., de Gennaro, B., Monetti, V., and de Gennaro, M. (2012) May the use of Italian volcanic zeolite-rich tuffs as additives in animal diet represent a risk for the human health. Period Mineral, 81, 393–407.Search in Google Scholar
Mercurio, M., Grilli, E., Odierna, P., Morra, V., Prohaska, T., Coppola, E., Grifa, C., Buondonno, A., and Langella, A. (2014) A “Geo-Pedo-Fingerprint” (GPF) as a tracer to detect univocal parent material-to-wine production chain in high quality vineyard districts, Campi Flegrei (Southern Italy). Geoderma, 230-231, 64–78.10.1016/j.geoderma.2014.04.006Search in Google Scholar
Mercurio, M., Bish, D.L., Cappelletti, P., de Gennaro, B., de Gennaro, M., Grifa, C., Izzo, F., Mercurio, V., Morra, V., and Langella, A. (2016a) The combined use of steam-treated bentonites and natural zeolites in the oenological refining process. Mineralogical Magazine, 80, 347–362.10.1180/minmag.2016.080.004Search in Google Scholar
Mercurio, M., Cappelletti, P., de Gennaro, B., de Gennaro, M., Bovera, F., Iannaccone, F., Grifa, C., Langella, A., Monetti, V., and Esposito, L. (2016b) The effect of digestive activity of pig gastro-intestinal tract on zeolite-rich rocks: An in vitro study. Microporous and Mesoporous Materials, 225, 133–136.10.1016/j.micromeso.2015.11.039Search in Google Scholar
Morra, V., Calcaterra, D., Cappelletti, P., Colella, A., Fedele, L., De’Gennaro, R., Langella, A., Mercurio, M., and de Gennaro, M. (2010) Urban geology: relationships between geological setting and architectural heritage of the Neapolitan area. Journal of the Virtual Explorer, 36, 1–60.10.3809/jvirtex.2010.00261Search in Google Scholar
Mozgawa, W., Król, M., and Barczyk, K. (2011) FT-IR studies of zeolites from different structural groups. CHEMIK nauka-technika-rynek, 1, 667–674.Search in Google Scholar
Oh, S., Shin, W.S., and Kim, H.T. (2016) Effects of pH, dissolved organic matter, and salinity on ibuprofen sorption on sediment. Environmental Science and Pollution Research, 23, 22882–22889.10.1007/s11356-016-7503-6Search in Google Scholar
Pansini, M., Colella, C., Caputo, D., de Gennaro, M., and Langella, A. (1996) Evaluation of phillipsite as cation exchanger in lead removal from water. Microporous Materials, 5, 357–364.10.1016/0927-6513(95)00071-2Search in Google Scholar
Pasquino, R., Di Domenico, M., Izzo, F., Gaudino, D., Vanzanella, V., Grizzuti, N., and de Gennaro, B. (2016) Rheology-sensitive response of zeolite-supported antiinflammatory drug systems. Colloids and Surfaces B: Biointerfaces, 146, 938–944.10.1016/j.colsurfb.2016.07.039Search in Google Scholar PubMed
Płuciennik-Koropczuk, E. (2014) Non-Steroid Anti-Infflamatory Drugs in Municipal Wastewater and Surface Waters (Niesteroidowe Leki Przeciwzaplane W Ściekach Mieskich I Wodach Powierzchniowych). Civil and Environmental Engineering Reports, 14.10.1515/ceer-2014-0026Search in Google Scholar
Sena, M.M., Freitas, C.B., Silva, L.C., Pérez, C.N., and de Paula, Y.O. (2007) Determinação espectrofotométrica simultânea de paracetamol e ibuprofeno em formulações farmacêuticas usando calibração multivariada. Química Nova, 30, 75–79.10.1590/S0100-40422007000100017Search in Google Scholar
Serri, C., de Gennaro, B., Catalanotti, L., Cappelletti, P., Langella, A., Mercurio, M., Mayol, L., and Biondi, M. (2016) Surfactant-modified phillipsite and chabazite as novel excipients for pharmaceutical applications? Microporous and Mesoporous Materials, 224, 143–148.10.1016/j.micromeso.2015.11.023Search in Google Scholar
Serri, C., de Gennaro, B., Quagliariello, V., Iaffaioli, R.V., De Rosa, G., Catalanotti, L., Biondi, M., and Mayol, L. (2017) Surface modified zeolite-based granulates for the sustained release of diclofenac sodium. European Journal of Pharmaceutical Sciences, 99, 202–208.10.1016/j.ejps.2016.12.019Search in Google Scholar PubMed
Sips, R. (1948) Combined form of Langmuir and Freundlich equations. Journal of Chemical Physics, 16, 490–495.10.1063/1.1746922Search in Google Scholar
Spiess, A.-N., and Neumeyer, N. (2010) An evaluation of R2 as an inadequate measure for nonlinear models in pharmacological and biochemical research: a Monte Carlo approach. BMC Pharmacology, 10, 6.10.1186/1471-2210-10-6Search in Google Scholar PubMed PubMed Central
Sullivan, E.J., Hunter, D.B., and Bowman, R.S. (1997) Topological and thermal properties of surfactant-modified clinoptilolite studied by tapping-mode atomic force microscopy and high-resolution thermogravimetric analysis. Clays and Clay Minerals, 45, 42–53.10.1346/CCMN.1997.0450105Search in Google Scholar
Tan, D., Yuan, P., Annabi-Bergaya, F., Yu, H., Liu, D., Liu, H., and He, H. (2013) Natural halloysite nanotubes as mesoporous carriers for the loading of ibuprofen. Microporous and Mesoporous Materials, 179, 89–98.10.1016/j.micromeso.2013.05.007Search in Google Scholar
Toth, J. (1971) State equations of the solid-gas interface layers. Acta chimica Academiae Scientiarum Hungaricae, 69, 311–328.Search in Google Scholar
USP-NF (2002) The United States Pharmacopeia and the National Formulary, 25th ed. United States Pharmacopeial Convention Inc., Rockville, Maryland.Search in Google Scholar
USP-NF (2002) (2003) The United States Pharmacopeia and the National Formulary, 26th ed. United States Pharmacopeial Convention Inc., Rockville, Maryland.Search in Google Scholar
Wang, S., and Peng, Y. (2010) Natural zeolites as effective adsorbents in water and wastewater treatment. Chemical Engineering Journal, 156, 11–24.10.1016/j.cej.2009.10.029Search in Google Scholar
Wray, P.S., Clarke, G.S., and Kazarian, S.G. (2011) Application of FTIR spectroscopic imaging to study the effects of modifying the pH microenvironment on the dissolution of ibuprofen from HPMC matrices. Journal of Pharmaceutical Sciences, 100, 4745–4755.10.1002/jps.22667Search in Google Scholar PubMed
Yadav, G., Bansal, M., Thakur, N., and Khare, P. (2013) Multilayer tablets and their drug release kinetic models for oral controlled drug delivery system. Middle-East Journal of Scientific Research, 16, 782–795.Search in Google Scholar
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Articles in the same Issue
- Review
- Biosilica as a source for inspiration in biological materials science
- Ab initio study of water speciation in forsterite: Importance of the entropic effect
- Surface-modified phillipsite-rich tuff from the Campania region (southern Italy) as a promising drug carrier: An ibuprofen sodium salt trial
- Structure of low-order hemimorphite produced in a Zn-rich environment by cyanobacterium Leptolingbya frigida
- Formation of dolomite catalyzed by sulfate-driven anaerobic oxidation of methane: Mineralogical and geochemical evidence from the northern South China Sea
- Anisotropic growth of olivine during crystallization in basalts from Hawaii: Implications for olivine fabric development
- Melting experiments on Fe–Si–S alloys to core pressures: Silicon in the core?
- High-pressure phase behavior and equations of state of ThO2 polymorphs
- Mafic inputs into the rhyolitic magmatic system of the 2.08 Ma Huckleberry Ridge eruption, Yellowstone
- Toward the wider application of 29Si NMR spectroscopy to paramagnetic transition metal silicate minerals and glasses: Fe(II), Co(II), and Ni(II) silicates
- Equations of state and phase boundary for stishovite and CaCl2-type SiO2
- Insight on gem opal formation in volcanic ash deposits from a supereruption: A case study through oxygen and hydrogen isotopic composition of opals from Lake Tecopa, California, U.S.A
- Revisiting the crystal structure of dickite: X-ray diffraction, solid-state NMR, and DFT calculations study
- Temperature and pressure effects on the partitioning of V and Sc between clinopyroxene and silicate melt: Implications for mantle oxygen fugacity
- Letter
- Why natural monazite never becomes amorphous: Experimental evidence for alpha self-healing
- New Mineral Names
- Book Review
- Book Review: Glaciovolcanism on Earth and Mars: Products, Processes and Paleoenvironmental Significance
Articles in the same Issue
- Review
- Biosilica as a source for inspiration in biological materials science
- Ab initio study of water speciation in forsterite: Importance of the entropic effect
- Surface-modified phillipsite-rich tuff from the Campania region (southern Italy) as a promising drug carrier: An ibuprofen sodium salt trial
- Structure of low-order hemimorphite produced in a Zn-rich environment by cyanobacterium Leptolingbya frigida
- Formation of dolomite catalyzed by sulfate-driven anaerobic oxidation of methane: Mineralogical and geochemical evidence from the northern South China Sea
- Anisotropic growth of olivine during crystallization in basalts from Hawaii: Implications for olivine fabric development
- Melting experiments on Fe–Si–S alloys to core pressures: Silicon in the core?
- High-pressure phase behavior and equations of state of ThO2 polymorphs
- Mafic inputs into the rhyolitic magmatic system of the 2.08 Ma Huckleberry Ridge eruption, Yellowstone
- Toward the wider application of 29Si NMR spectroscopy to paramagnetic transition metal silicate minerals and glasses: Fe(II), Co(II), and Ni(II) silicates
- Equations of state and phase boundary for stishovite and CaCl2-type SiO2
- Insight on gem opal formation in volcanic ash deposits from a supereruption: A case study through oxygen and hydrogen isotopic composition of opals from Lake Tecopa, California, U.S.A
- Revisiting the crystal structure of dickite: X-ray diffraction, solid-state NMR, and DFT calculations study
- Temperature and pressure effects on the partitioning of V and Sc between clinopyroxene and silicate melt: Implications for mantle oxygen fugacity
- Letter
- Why natural monazite never becomes amorphous: Experimental evidence for alpha self-healing
- New Mineral Names
- Book Review
- Book Review: Glaciovolcanism on Earth and Mars: Products, Processes and Paleoenvironmental Significance