Home Physical Sciences Calcium (Ti,Zr) hexaorthophosphate bioceramics for electrically stimulated biomedical implant devices: A position paper
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Calcium (Ti,Zr) hexaorthophosphate bioceramics for electrically stimulated biomedical implant devices: A position paper

  • Robert B. Heimann EMAIL logo
Published/Copyright: October 30, 2017
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American Mineralogist
From the journal American Mineralogist Volume 102 Issue 11

Abstract

Osseointegration of biomedical implants as well as healing of broken bones are supported by novel bioceramic materials that, owing to their engineered ionic conductivity, in the presence of an electric field provide accumulation of negative electrical charges close to the interface between an implant and living bone tissue, thus stimulating the rate of bone growth. In this position paper, the structure as well as the chemical, electrical, and biomedical properties of Ca (Ti,Zr) hexaorthophosphates are reviewed. In addition, based on evaluation of the material’s properties, a conceptual configuration of a capacity-coupled bone growth stimulator will be presented. The advantage of the proposed novel device over already existing bone-growth stimulators is its provision of the intimate contact of a capacity-coupled electric field with the growing bone tissue as opposed to an externally applied inductively coupled electromagnetic field, which suffers substantial attenuation when transmitted through soft tissue covering the locus of bone growth. To achieve higher ionic conductivity in Ca (Ti,Zr) hexaorthophosphates, aliovalent doping with highly mobile Na or Li ions intercalated into the only partially occupied M1 sites appears to be a suitable route.

Keywords: Bioceramics; calcium hexaorthophosphate; plasma spraying; solubility; osseoconductivity; bone growth; bone growth stimulation; Biomaterials—Mineralogy Meets Medicine

Special collection papers can be found online at http://www.minsocam.org/MSA/AmMin/special-collections.html.

Acknowledgements

Thanks are due to Jill D. Pasteris, Washington University, St. Louis, for critical reading an earlier version of this contribution.

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Received: 2017-4-18
Accepted: 2017-7-3
Published Online: 2017-10-30
Published in Print: 2017-11-27

© 2017 Walter de Gruyter Berlin/Boston

Articles in the same Issue

  1. Highlights and Breakthroughs
  2. Rutile: A novel recorder of high-fo2 fluids in subduction zones
  3. Highlights and Breakthroughs
  4. Granites and rhyolites: Messages from Hong Kong, courtesy of zircon
  5. Review
  6. Do Fe-Ti-oxide magmas exist? Probably not!
  7. Special Collection: Biomaterials—Mineralogy Meets Medicine
  8. Calcium (Ti,Zr) hexaorthophosphate bioceramics for electrically stimulated biomedical implant devices: A position paper
  9. Special Collection: Water in Nominally Hydrous and Anhydrous Minerals
  10. Raman spectroscopy of water-rich stishovite and dense high-pressure silica up to 55 GPa
  12. Tracking the evolution of Late Mesozoic arc-related magmatic systems in Hong Kong using in-situ U-Pb dating and trace element analyses in zircon
  14. Defect contributions to the heat capacities and stabilities of some chain, ring, and sheet silicates, with implications for mantle minerals
  16. Phase transition in SiC from zinc-blende to rock-salt structure and implications for carbon-rich extrasolar planets
  18. Non-destructive, multi-method, internal analysis of multiple inclusions in a single diamond: First occurrence of mackinawite (Fe,Ni)1+xS
  20. The fate of ammonium in phengite at high temperature
  22. Parameterized lattice strain models for REE partitioning between amphibole and silicate melt
  24. Unusual replacement of Fe-Ti oxides by rutile during retrogression in amphibolite-hosted veins (Dabie UHP terrane): A mineralogical record of fluid-induced oxidation processes in exhumed UHP slabs
  26. Crystallization experiments in rhyolitic systems: The effect of temperature cycling and starting material on crystal size distribution
  28. Dolomite dissociation indicates ultra-deep (>150 km) subduction of a garnet-bearing dunite block (the Sulu UHP terrane)
  30. Microscopic strain in a grossular-pyrope solution anti-correlates with excess volume through local Mg-Ca cation arrangement, more strongly at high Ca/Mg ratio
  32. Ferruginous seawater facilitates the transformation of glauconite to chamosite: An example from the Mesoproterozoic Xiamaling Formation of North China
  34. Charleshatchettite, CaNb4O10(OH)2·8H2O, a new mineral from Mont Saint-Hilaire, Québec, Canada: Description, crystal-structure determination, and origin
  36. New Mineral Names
  38. Erratum
  39. Book Review
  40. Non-Traditional Stable Isotopes
https://doi.org/10.2138/am-2017-6165
Keywords for this article
Bioceramics; calcium hexaorthophosphate; plasma spraying; solubility; osseoconductivity; bone growth; bone growth stimulation; Biomaterials—Mineralogy Meets Medicine

Articles in the same Issue

  1. Highlights and Breakthroughs
  2. Rutile: A novel recorder of high-fo2 fluids in subduction zones
  3. Highlights and Breakthroughs
  4. Granites and rhyolites: Messages from Hong Kong, courtesy of zircon
  5. Review
  6. Do Fe-Ti-oxide magmas exist? Probably not!
  7. Special Collection: Biomaterials—Mineralogy Meets Medicine
  8. Calcium (Ti,Zr) hexaorthophosphate bioceramics for electrically stimulated biomedical implant devices: A position paper
  9. Special Collection: Water in Nominally Hydrous and Anhydrous Minerals
  10. Raman spectroscopy of water-rich stishovite and dense high-pressure silica up to 55 GPa
  12. Tracking the evolution of Late Mesozoic arc-related magmatic systems in Hong Kong using in-situ U-Pb dating and trace element analyses in zircon
  14. Defect contributions to the heat capacities and stabilities of some chain, ring, and sheet silicates, with implications for mantle minerals
  16. Phase transition in SiC from zinc-blende to rock-salt structure and implications for carbon-rich extrasolar planets
  18. Non-destructive, multi-method, internal analysis of multiple inclusions in a single diamond: First occurrence of mackinawite (Fe,Ni)1+xS
  20. The fate of ammonium in phengite at high temperature
  22. Parameterized lattice strain models for REE partitioning between amphibole and silicate melt
  24. Unusual replacement of Fe-Ti oxides by rutile during retrogression in amphibolite-hosted veins (Dabie UHP terrane): A mineralogical record of fluid-induced oxidation processes in exhumed UHP slabs
  26. Crystallization experiments in rhyolitic systems: The effect of temperature cycling and starting material on crystal size distribution
  28. Dolomite dissociation indicates ultra-deep (>150 km) subduction of a garnet-bearing dunite block (the Sulu UHP terrane)
  30. Microscopic strain in a grossular-pyrope solution anti-correlates with excess volume through local Mg-Ca cation arrangement, more strongly at high Ca/Mg ratio
  32. Ferruginous seawater facilitates the transformation of glauconite to chamosite: An example from the Mesoproterozoic Xiamaling Formation of North China
  34. Charleshatchettite, CaNb4O10(OH)2·8H2O, a new mineral from Mont Saint-Hilaire, Québec, Canada: Description, crystal-structure determination, and origin
  36. New Mineral Names
  38. Erratum
  39. Book Review
  40. Non-Traditional Stable Isotopes
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