Pharmacological and toxicological profile of the Stachys lavandulifolia Vahl: a comprehensive review

Serkan Yilmaz; Hafize Fidan

doi:10.1515/znc-2024-0222

Article

Pharmacological and toxicological profile of the Stachys lavandulifolia Vahl: a comprehensive review

Serkan Yilmaz and Hafize Fidan

Published/Copyright: December 31, 2024

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From the journal Zeitschrift für Naturforschung C Volume 80 Issue 9-10

Abstract

Medicinal plants play a vital role in traditional medicine. They offer remedies for various ailments and contribute significantly to human health. Stachys lavandulifolia Vahl is herbaceous plant from the Lamiaceae family, native to Türkiye, Iran, and the Caucasus. Known for its medicinal properties and ornamental value. It grows in various habitats and displays high phenotypic variability. Major essential oil constituents are α-pinene, (E)-caryophyllene, germacrene D, Δ-cadinene, and others. These constituents contribute to its medicinal properties. S. lavandulifolia has significant potential for health-related applications due to its diverse pharmacological effects. Clinical and laboratory studies have shown multiple benefits like anti-inflammatory, antioxidant, anxiolytic, antitumor, anticholinesterase, antimicrobial, analgesic, neuroprotective, antidiabetic, and gastrointestinal benefits. Furthermore, studies have shown potential in extending human lifespan, reducing fatigue, nausea, vomiting associated with primary dysmenorrhea, and managing PCOS-induced abnormal uterine bleeding. However, some potential toxicity issues about abortion and renal toxicity were also reported. Ongoing research and clinical trials are essential to fully understand its benefits and safety profile.

Keywords: Stachys lavandulifolia Vahl; nutritional aspects; pharmacology; health benefits; toxicology

Corresponding author: Serkan Yilmaz, Institute for Forensic Sciences, Faculty of Nursing, Ankara University, Altındağ, 06230, Ankara, Türkiye, E-mail: serkanyilmaz@ankara.edu.tr

Research ethics: Not applicable.
Informed consent: Not applicable.
Author contributions: All authors have equal contribution.
Use of Large Language Models, AI and Machine Learning Tools: None declared.
Conflict of interest: The author states no conflict of interest.
Research funding: None declared.
Data availability: Not applicable.

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Received: 2024-09-23

Accepted: 2024-12-13

Published Online: 2024-12-31

Published in Print: 2025-09-25

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Keywords for this article

Stachys lavandulifolia Vahl; nutritional aspects; pharmacology; health benefits; toxicology