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Review perspective on advanced nutrachemicals and anterior cruciate ligament rehabilitation

  • Dai Haojie , Sohini Mukherjee and Tanima Bhattacharya ORCID logo EMAIL logo
Published/Copyright: October 24, 2024
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Abstract

Anterior cruciate ligament (ACL) injuries are prevalent among athletes, necessitating surgical intervention followed by comprehensive rehabilitation. Recently, the integration of nutraceuticals – bioactive compounds from food sources – into rehabilitation protocols has shown promise in enhancing recovery outcomes. This review explores the potential benefits of various nutraceuticals, including omega-3 fatty acids, collagen supplements, vitamin D, glucosamine and chondroitin, curcumin, and branched-chain amino acids (BCAAs), in ACL rehabilitation. These nutraceuticals offer anti-inflammatory properties, support tissue repair, and improve joint and muscle health, which are critical during the rehabilitation process. Despite encouraging preclinical findings, there is a need for robust clinical trials to confirm their efficacy and establish optimal dosages and formulations. Personalized nutrition plans and interdisciplinary collaboration among healthcare providers are essential for optimizing patient care. This perspective underscores the potential of advanced nutraceuticals to revolutionize ACL rehabilitation, paving the way for faster and more effective recovery pathways.


Corresponding author: Tanima Bhattacharya, Faculty of Applied Science, Lincoln University College, Petaling Jaya, Selangor Darul Ehsan 47301, Malaysia, E-mail:
Dai Haojie and Tanima Bhattacharya contributed equally to this work.
  1. Research ethics: Not applicable.

  2. Informed consent: Not applicable.

  3. Author contributions: D.H., T.B.: conceptualization, D.H., S.M., T.B.: data collection,writing original draft, reviewing, editing, S.M., T.B.: Visualization, T.B.: Supervision.

  4. Use of Large Language Models, AI and Machine Learning Tools: Parafrasing tool Quilbot used.

  5. Conflict of interest: Authors declared no conflicts of interest.

  6. Research funding: No funds received.

  7. Data availability: Not applicable.

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Received: 2024-08-07
Accepted: 2024-10-05
Published Online: 2024-10-24
Published in Print: 2025-07-28

© 2024 Walter de Gruyter GmbH, Berlin/Boston

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