Chitosan/hydroxyapatite biomimetic material loaded with Curcuma longa L. essential oil
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Shengnan Kong
Shengnan Kong is a postgraduate in Anhui university of Chinese Medicine. Her main fields of research are mass transfer and separation in pharmaceutical processes.
Ya Xu is a postgraduate in Anhui university of Chinese Medicine. Her main fields of research are mass transfer and separation in pharmaceutical processes.
Feng Li is a postgraduate tutor. His main fields of research are medicinal chemical synthesis.
Prof. Chuanrun Li is a teacher at Anhui University of Chinese Medicine. His research interests are in the fields of organic substances, fine chemicals and environmental protection.
and
Huchuan Wang
Prof. Huchuan Wang is a teacher at Anhui University of Chinese Medicine. His main fields of research are application of water-soluble polymers in industrial water systems and green chemical.
Abstract
In this work, Curcuma longa L. essential oil (CEO) was loaded into the modified chitosan/hydroxyapatite (PMCH) biomimetic material and the PMCH/CEO was characterized by FTIR, SEM, XRD and BET. The main components of CEO were ar-tumerone (21.97 %), ar-curcumene (13.00 %), β-sesquiphellandrene (13.00 %) and curlone (8.57 %), which was analyzed by GC-MS. The stability of PMCH/CEO was investigated at different relative humidities (33 % and 96 %) and temperatures (60 °C and 80 °C) conditions. The ability of CEO and PMCH/CEO to scavenge DPPH radicals and ABTS radicals is used to evaluate the antioxidant acivity. The concentration of the sample was determined by the CCK-8 method, and the lipopolysaccharide-induced RAW264.7 cell inflammation model was established to evaluate the anti-inflammatory effect. CEO and PMCH/CEO showed good antioxidant activity. CEO and PMCH/CEO also had significant inhibitory effects on NO, IL-6 and TNF-α, and the inhibition rates were 85.62 %, 55.82 % and 27.7 %, respectively. This study shows that CEO-loaded PMCH has potential development prospects in food, medicine and other related fields.
About the authors
Shengnan Kong is a postgraduate in Anhui university of Chinese Medicine. Her main fields of research are mass transfer and separation in pharmaceutical processes.
Ya Xu is a postgraduate in Anhui university of Chinese Medicine. Her main fields of research are mass transfer and separation in pharmaceutical processes.
Feng Li is a postgraduate tutor. His main fields of research are medicinal chemical synthesis.
Prof. Chuanrun Li is a teacher at Anhui University of Chinese Medicine. His research interests are in the fields of organic substances, fine chemicals and environmental protection.
Prof. Huchuan Wang is a teacher at Anhui University of Chinese Medicine. His main fields of research are application of water-soluble polymers in industrial water systems and green chemical.
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Research ethics: Not applicable.
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Informed consent: Not applicable.
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Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Use of Large Language Models, AI and Machine Learning Tools: None declared.
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Conflict of interest: The authors state no conflict of interest.
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Research funding: This work is supported by the National Key Research and Development Program of China [2022YFB3805102], Key Project of Natural Science Research of Anhui Universities [2024AH051029].
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Data availability: Not applicable.
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© 2025 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Review Article
- Precision-engineered nanomaterials: unlocking the potential of water-in-oil microemulsions for the controlled synthesis, morphology design, and future innovations
- Micellar Catalysis
- Oxidation of l-tyrosine by diperiodatocuprate(III) in CPC micellar medium, facilitated by Ru(III)
- A comprehensive spectral study of dye-surfactant complex formation by Xylenol Orange with selective aqueous micellar media of CPC, rhamnolipids and saponin
- Physical Chemistry
- Preparation of polyoxyethylene(n) monodehydroabietates and their physicochemical properties
- Surface modification of synthetic montmorillonite as thickener: rheological behavior and tribological properties at high load and high temperature
- Drug Delivery System
- Exploring fatty acid-amino acid conjugate for the development of self-assembling, pH-sensitive vesicles for targeted anticancer drug delivery
- Novel Sufactants
- Double headed alkyl triazole glycosides – alternatives for APGs with increased hydrophilicity part 1: synthesis and physicochemical properties
- Synthesis and defoaming properties of two sulfonate surfactants from trisiloxane
- Application
- Criteria for a surfactant to be used sequentially as a grinding aid and collector
- Chitosan/hydroxyapatite biomimetic material loaded with Curcuma longa L. essential oil
Articles in the same Issue
- Frontmatter
- Review Article
- Precision-engineered nanomaterials: unlocking the potential of water-in-oil microemulsions for the controlled synthesis, morphology design, and future innovations
- Micellar Catalysis
- Oxidation of l-tyrosine by diperiodatocuprate(III) in CPC micellar medium, facilitated by Ru(III)
- A comprehensive spectral study of dye-surfactant complex formation by Xylenol Orange with selective aqueous micellar media of CPC, rhamnolipids and saponin
- Physical Chemistry
- Preparation of polyoxyethylene(n) monodehydroabietates and their physicochemical properties
- Surface modification of synthetic montmorillonite as thickener: rheological behavior and tribological properties at high load and high temperature
- Drug Delivery System
- Exploring fatty acid-amino acid conjugate for the development of self-assembling, pH-sensitive vesicles for targeted anticancer drug delivery
- Novel Sufactants
- Double headed alkyl triazole glycosides – alternatives for APGs with increased hydrophilicity part 1: synthesis and physicochemical properties
- Synthesis and defoaming properties of two sulfonate surfactants from trisiloxane
- Application
- Criteria for a surfactant to be used sequentially as a grinding aid and collector
- Chitosan/hydroxyapatite biomimetic material loaded with Curcuma longa L. essential oil
