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Telemetric multi-sensor system for medical applications – The approach

  • Jens Weidenmüller

    J. Weidenmüller received the Diploma degree in physical engineering from the RheinAhrCampus in Remagen in 2007. He subsequently worked as scientific assistant in the field of sensor development, from 2007 to 2010 at the RheinAhrCampus and from 2011 to 2014 at the Hochschule RuhrWest. From 2010 to 2014 he was additionally a PhD student at the Technical University Chemnitz. In July 2014 he obtained the academic degree (Dr.-Ing.) with the thesis: “Optimization of encircling eddy current sensors for online monitoring of hot rolled round steel bars”. Since 2014 he works in the business field pressure sensor systems within Fraunhofer IMS and lectures electrical engineering at the Hochschule RuhrWest.

    Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

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    , Christian Walk

    C. Walk received the B.Sc. and M.Sc. degrees from the University of Freiburg, Germany, in 2009 and 2012, respectively. He studied microsystems engineering at the University of Freiburg with a focus on optics and process technologies. In 2012 he was a Research Assistant at Fraunhofer Institute for Solar Energy Systems (ISE), Freiburg, working in the field of optics and micro and nanostructured functional surfaces. Since 2012 he is with Fraunhofer IMS. From 2012 until 2014 he was a Research Assistant and since 2014 he is working as PhD student in the field of post-CMOS sensor development.

    Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

    , Özgü Dogan

    Ö. Dogan received the B.Sc. and M.Sc. degrees from the Technical University of Berlin (TUB), Germany, in 2013 and 2015, respectively. She studied electrical engineering with a focus on microsystems and medical-electronic systems. From 2011 until 2015 she was a student assistant at the Department of High-Frequency and Semiconductor System Technologies at TUB. Since 2015 she is with Fraunhofer IMS and is working as PhD student in the field of advanced implant encapsulations.

    Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

    , Pierre Gembaczka

    P. Gembaczka received the B.Sc. and M.Sc. degrees from the University of Applied Sciences Gelsenkirchen, Germany, in 2008 and 2010, respectively. He studied microsystems engineering at the University of Applied Sciences Gelsenkirchen. From 2011 to 2015 he was PhD student at the Fraunhofer IMS in cooperation with the Department of Electrical Engineering and Information Technology at the University Duisburg-Essen. In July 2015 he obtained the academic degree (Dr.-Ing.) with the thesis: “Development of a hermetically encapsulated microsystem pressure sensing system for use as a biosensor in aqueous media”. Since 2011 he works at the Fraunhofer IMS in the business Field: “Pressure Sensor Systems”.

    Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

    , Alexander Stanitzki

    A. Stanitzki received the Diploma degree in electrical engineering from the Ruhr-University Bochum in 2008. From 2007 to 20011 he worked at advICo microelectronics GmbH as an IC design engineer for RF-mixed-signal and radhard applications. Since 2012 he is leading the Mixed Signal IC Design group within Fraunhofer IMS, with a focus on energy harvesting medical implants, industrial precision sensor readout ICs and functional safety in analog ICs.

    Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

    and Michael Görtz

    M. Görtz received his Diploma from Niederrhein University of Applied Sciences in 2001 in electrical engineering with focus on electrical / optical communication and the production technologies of micro systems. From 2001 to 2004 he was at Fraunhofer IMS to design and test neuronal vision prosthesis with micro system technologies. Between 03/2004 and 02/2005 Institute of Materials in Electrical Engineering 1 at RWTH Aachen University working on active implantable medical devices. Since 03/2005 he is back at Fraunhofer IMS and responsible for development of medical implants. Actually he is Group manager and head of the business field Pressure Sensor Systems.

    Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

Published/Copyright: December 20, 2016

Abstract

Long-term monitoring of hemodynamics can be achieved by an implantable and telemetric multi-sensor system. A concept to realize a system with high miniaturization level is presented. The requirements regarding a multifunctional transponder ASIC (application specific integrated circuit), which should combine signal processing, telemetric communication and additional sensors in one chip, are introduced. Capacitive pressure sensors showing low power consumption were tested with laboratory setups with respect to the integration in this concept. First results were achieved and discussed concerning two potential assembly technologies for the integration of a pressure sensor. Finally, hermetic sealing and implant encapsulation technologies are proposed for further implant miniaturization.

Zusammenfassung

Durch die Einführung von implantierbaren und telemetrisch auslesbaren Sensorsystemen wird eine Langzeitüberwachung für den Einsatz im Blutkreislauf angestrebt. In diesem Beitrag wird ein Konzept für ein minaturisiertes System, welches unter anderem für diese Messaufgabe geeignet ist, vorgestellt. Zunächst werden die Anforderungen an den mutifunktionalen Transponder-ASIC (anwendungsspezifische integrierte Schaltung) erarbeitet. Dieser ASIC vereint die Signalverarbeitung aller Messdaten, die telemetrische Kommunikation mit einem extrakorporalem Lesegerät und wegen der hohen Minaturisierung bereits einige Sensoren. Zur Messung des Blutdrucks soll ein kapazitiver Drucksensor mit einer sehr geringen Leistungsaufnahme implementiert werden. Dieser wurde bereits erfolgreich etabliert und erste Ergebnisse werden vorgestellt. Für die Integration in das System werden nachfolgend zwei mögliche AVT (Aufbau- und Verbindungstechnik) Konzepte zur Integration in das Gesamtsystem diskutiert. Der Beitrag wird mit der Vorstellung eines neuartigen Verkapselungskonzept abgeschlossen, welches die Anforderungen, die technisch für einen Implantatbetrieb notwendig sind, erfüllen soll, jedoch deutliche Vorteile hinsichtlich der Miniaturisierung des Implantats gegenüber bisherigen Konzepten aufweist.

About the authors

Jens Weidenmüller

J. Weidenmüller received the Diploma degree in physical engineering from the RheinAhrCampus in Remagen in 2007. He subsequently worked as scientific assistant in the field of sensor development, from 2007 to 2010 at the RheinAhrCampus and from 2011 to 2014 at the Hochschule RuhrWest. From 2010 to 2014 he was additionally a PhD student at the Technical University Chemnitz. In July 2014 he obtained the academic degree (Dr.-Ing.) with the thesis: “Optimization of encircling eddy current sensors for online monitoring of hot rolled round steel bars”. Since 2014 he works in the business field pressure sensor systems within Fraunhofer IMS and lectures electrical engineering at the Hochschule RuhrWest.

Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

Christian Walk

C. Walk received the B.Sc. and M.Sc. degrees from the University of Freiburg, Germany, in 2009 and 2012, respectively. He studied microsystems engineering at the University of Freiburg with a focus on optics and process technologies. In 2012 he was a Research Assistant at Fraunhofer Institute for Solar Energy Systems (ISE), Freiburg, working in the field of optics and micro and nanostructured functional surfaces. Since 2012 he is with Fraunhofer IMS. From 2012 until 2014 he was a Research Assistant and since 2014 he is working as PhD student in the field of post-CMOS sensor development.

Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

Özgü Dogan

Ö. Dogan received the B.Sc. and M.Sc. degrees from the Technical University of Berlin (TUB), Germany, in 2013 and 2015, respectively. She studied electrical engineering with a focus on microsystems and medical-electronic systems. From 2011 until 2015 she was a student assistant at the Department of High-Frequency and Semiconductor System Technologies at TUB. Since 2015 she is with Fraunhofer IMS and is working as PhD student in the field of advanced implant encapsulations.

Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

Pierre Gembaczka

P. Gembaczka received the B.Sc. and M.Sc. degrees from the University of Applied Sciences Gelsenkirchen, Germany, in 2008 and 2010, respectively. He studied microsystems engineering at the University of Applied Sciences Gelsenkirchen. From 2011 to 2015 he was PhD student at the Fraunhofer IMS in cooperation with the Department of Electrical Engineering and Information Technology at the University Duisburg-Essen. In July 2015 he obtained the academic degree (Dr.-Ing.) with the thesis: “Development of a hermetically encapsulated microsystem pressure sensing system for use as a biosensor in aqueous media”. Since 2011 he works at the Fraunhofer IMS in the business Field: “Pressure Sensor Systems”.

Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

Alexander Stanitzki

A. Stanitzki received the Diploma degree in electrical engineering from the Ruhr-University Bochum in 2008. From 2007 to 20011 he worked at advICo microelectronics GmbH as an IC design engineer for RF-mixed-signal and radhard applications. Since 2012 he is leading the Mixed Signal IC Design group within Fraunhofer IMS, with a focus on energy harvesting medical implants, industrial precision sensor readout ICs and functional safety in analog ICs.

Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

Michael Görtz

M. Görtz received his Diploma from Niederrhein University of Applied Sciences in 2001 in electrical engineering with focus on electrical / optical communication and the production technologies of micro systems. From 2001 to 2004 he was at Fraunhofer IMS to design and test neuronal vision prosthesis with micro system technologies. Between 03/2004 and 02/2005 Institute of Materials in Electrical Engineering 1 at RWTH Aachen University working on active implantable medical devices. Since 03/2005 he is back at Fraunhofer IMS and responsible for development of medical implants. Actually he is Group manager and head of the business field Pressure Sensor Systems.

Fraunhofer Institute for Microelectronic Circiuts and Systems IMS, Finkenstr. 61, 47057 Duisburg

Received: 2016-11-23
Accepted: 2016-11-29
Published Online: 2016-12-20
Published in Print: 2017-1-28

©2016 Walter de Gruyter Berlin/Boston

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