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A systematic review and meta-analysis of the preclinical and clinical results of low-field magnetic stimulation in cognitive disorders

  • Nicholas Mellon ORCID logo EMAIL logo , Brett Robbins ORCID logo , Rebekah van Bruggen and Yanbo Zhang
Published/Copyright: April 29, 2024
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Reviews in the Neurosciences
From the journal Reviews in the Neurosciences Volume 35 Issue 6

Abstract

Cognitive disorders such as major depressive disorder and bipolar disorder severely compromise brain function and neuronal activity. Treatments to restore cognitive abilities can have severe side effects due to their intense and excitatory nature, in addition to the fact that they are expensive and invasive. Low-field magnetic stimulation (LFMS) is a novel non-invasive proposed treatment for cognitive disorders. It repairs issues in the brain by altering deep cortical areas with treatments of low-intensity magnetic stimulation. This paper aims to summarize the current literature on the effects and results of LFMS in cognitive disorders. We developed a search strategy to identify relevant studies utilizing LFMS and systematically searched eight scientific databases. Our review suggests that LFMS could be a viable and effective treatment for multiple cognitive disorders, especially major depressive disorder. Additionally, longer, more frequent, and more personalized LFMS treatments tend to be more efficacious.

Keywords: bipolar disorder; low-field magnetic stimulation; major depressive disorder; novel therapy; non-invasive
Corresponding author: Nicholas Mellon, Faculty of Medicine and Dentistry, The University of Alberta, Edmonton, AB, T6G 2E1, Canada, E-mail:

Funding source: Natural Sciences and Engineering Research Council of Canada

Award Identifier / Grant number: USRA

  1. Research ethics: Not applicable.

  2. Author contributions: The authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: The authors state no conflict of interest.

  4. Research funding: Natural Science and Engineering Research Council of Canada Undergraduate Student Research Award (NSERC USRA).

  5. Data availability: Not applicable.

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Supplementary Material

This article contains supplementary material (https://doi.org/10.1515/revneuro-2024-0023).

Received: 2024-02-01
Accepted: 2024-03-18
Published Online: 2024-04-29
Published in Print: 2024-08-27

© 2024 Walter de Gruyter GmbH, Berlin/Boston

Articles in the same Issue

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  2. The impact of poverty and socioeconomic status on brain, behaviour, and development: a unified framework
  3. A systematic review and meta-analysis of the preclinical and clinical results of low-field magnetic stimulation in cognitive disorders
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https://doi.org/10.1515/revneuro-2024-0023
Keywords for this article
bipolar disorder; low-field magnetic stimulation; major depressive disorder; novel therapy; non-invasive

Articles in the same Issue

  1. Frontmatter
  2. The impact of poverty and socioeconomic status on brain, behaviour, and development: a unified framework
  3. A systematic review and meta-analysis of the preclinical and clinical results of low-field magnetic stimulation in cognitive disorders
  4. Research advancements on nerve guide conduits for nerve injury repair
  5. From nasal respiration to brain dynamic
  6. Cerebral autoregulation, spreading depolarization, and implications for targeted therapy in brain injury and ischemia
  7. Theta burst stimulation for enhancing upper extremity motor functions after stroke: a systematic review of clinical and mechanistic evidence
  8. Functional alterations in overweight/obesity: focusing on the reward and executive control network
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