Environmental arsenic exposure and its toxicological effect on thyroid function: a systematic review
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Adeleh Esform
Abstract
Objectives
This study was performed to review epidemiological evidence related to Arsenic (As) effects on the thyroid function by focusing on the serum thyroid hormone concentration.
Content
As, one of the main pollutants, has been recognized as an endocrine-disrupting agent that may affect the function of thyroid as shown by experimental studies.
Summary
This systematic study indicates the association between As exposure and thyroid dysfunction. The studies have shown an association between serum and urine concentration of arsenic and thyroid dysfunction. Most of them reported the association between increase in the serum or urine As levels and decrease in the triiodothyronine (T3) and thyroxine (T4), and also elevation in the thyrotropic hormone (TSH) levels.
Outlook
Our findings related to the effects of As on the function of thyroid in humans are still limited and future studies should be done to address this question.
Funding source: Birjand University of Medical Sciences
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Research funding: Birjand University of Medical Sciences financially supported this study.
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Author contributions: Substantial contributions to the conception or design of the work; Ali Naghizadeh. The acquisition of data: Adeleh Esform. Drafting the work: Adeleh Esfrom, Tahereh Seed Samarghandian and Ali Naghizadeh. Revising manuscript critically for important intellectual content: Ali Naghizadeh, Saeed Samarghandian. Final approval of the version to be published: All authors approved the final version.
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Competing interests: The authors declare that there is no conflict of interest.
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Informed consent: Not applicable.
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Ethical approval: Not applicable.
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Availability of data and materials: The data that support the findings of this study are available in the manuscript.
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This paper is based on the part of results of a research project supported by Birjand University of Medical Sciences coded 2039 and ethical coded IR.BUMS.REC.1399.395.
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© 2021 Walter de Gruyter GmbH, Berlin/Boston
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- Housing and health in vulnerable social groups: an overview and bibliometric analysis
- Environmental arsenic exposure and its toxicological effect on thyroid function: a systematic review
- Letters to the Editor
- Comments on Martin Pall, “Millimeter (MM) wave and microwave frequency radiation produce deeply penetrating effects: the biology and the physics”, Rev Environ Health 2021;37:247–58.
- Comments on Pall’s “Millimeter (MM) wave and microwave frequency radiation produce deeply penetrating effects: the biology and the physics”
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- Comments on the article by Dariusz Leszczynski: Review of the scientific evidence on the individual sensitivity to electromagnetic fields (EHS). Rev Environ Health 2021
Articles in the same Issue
- Frontmatter
- Mini Reviews
- Unani medicinal herbs as potential air disinfectants: an evidence-based review
- Safety assessment of natural products in Malaysia: current practices, challenges, and new strategies
- Environmental and occupational health on the Navajo Nation: a scoping review
- Review Articles
- Understanding Holism in the light of principle underlying practice of Unani Medicine
- Investigating the field effectiveness of respirators against metal particle exposure in various workplaces: a systematic review
- To which extent are per-and poly-fluorinated substances associated to metabolic syndrome?
- Reactive nitrogen compounds and their influence on human health: an overview
- Millimeter (MM) wave and microwave frequency radiation produce deeply penetrating effects: the biology and the physics
- Air pollution increases the risk of pulmonary embolism: a meta-analysis
- Housing and health in vulnerable social groups: an overview and bibliometric analysis
- Environmental arsenic exposure and its toxicological effect on thyroid function: a systematic review
- Letters to the Editor
- Comments on Martin Pall, “Millimeter (MM) wave and microwave frequency radiation produce deeply penetrating effects: the biology and the physics”, Rev Environ Health 2021;37:247–58.
- Comments on Pall’s “Millimeter (MM) wave and microwave frequency radiation produce deeply penetrating effects: the biology and the physics”
- ‘Proof of EHS beyond all reasonable doubt’. Comment on: Leszczynski D. Review of the scientific evidence on the individual sensitivity to electromagnetic fields (EHS). Rev Environ Health 2021; https://doi.org/10.1515/reveh-2021-0038. Online ahead of print
- Why scientifically unfounded and misleading claim should be dismissed to make true research progress in the acknowledgment of electrohypersensibility as a new worldwide emerging pathology
- Comments on the article by Dariusz Leszczynski: Review of the scientific evidence on the individual sensitivity to electromagnetic fields (EHS). Rev Environ Health 2021
